S
Sasithon Pukrittayakamee
Researcher at Mahidol University
Publications - 209
Citations - 13552
Sasithon Pukrittayakamee is an academic researcher from Mahidol University. The author has contributed to research in topics: Malaria & Plasmodium falciparum. The author has an hindex of 60, co-authored 195 publications receiving 11873 citations. Previous affiliations of Sasithon Pukrittayakamee include John Radcliffe Hospital & Novartis.
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Journal ArticleDOI
Spread of Artemisinin Resistance in Plasmodium falciparum Malaria
Elizabeth A. Ashley,Mehul Dhorda,Rick M. Fairhurst,Chanaki Amaratunga,Pharath Lim,Seila Suon,Sokunthea Sreng,Jennifer M. Anderson,Mao S,Sam B,Chantha Sopha,Char Meng Chuor,Chea Nguon,Siv Sovannaroth,Sasithon Pukrittayakamee,Podjanee Jittamala,Kesinee Chotivanich,K Chutasmit,C Suchatsoonthorn,R Runcharoen,Tran Tinh Hien,Nguyen Thuy-Nhien,Thanh Nv,Nguyen Hoan Phu,Ye Htut,Han Kt,Kyin Hla Aye,Olugbenga A. Mokuolu,Rasaq Olaosebikan,Olaleke Oluwasegun Folaranmi,Mayfong Mayxay,Maniphone Khanthavong,Bouasy Hongvanthong,Paul N. Newton,M A Onyamboko,Caterina I. Fanello,Antoinette Tshefu,Neelima Mishra,Neena Valecha,Aung Pyae Phyo,François Nosten,Yi P,Rupam Tripura,Steffen Borrmann,Mahfudh Bashraheil,Judy Peshu,M A Faiz,Aniruddha Ghose,M A Hossain,Rasheda Samad,M. R. Rahman,Manal Hasan,Ashraful Islam,Olivo Miotto,Roberto Amato,Bronwyn MacInnis,Jim Stalker,Dominic P. Kwiatkowski,Zbynek Bozdech,Atthanee Jeeyapant,Phaik Yeong Cheah,Tharisara Sakulthaew,Jeremy Chalk,Benjamas Intharabut,Kamolrat Silamut,Lee Sj,Benchawan Vihokhern,Chanon Kunasol,Mallika Imwong,Joel Tarning,Taylor Wj,Shunmay Yeung,Charles J. Woodrow,Jennifer A. Flegg,Debashish Das,Jennifer L. Smith,Meera Venkatesan,Christopher V. Plowe,Kasia Stepniewska,Philippe J Guerin,Arjen M. Dondorp,Nicholas P. J. Day,Nicholas J. White +82 more
TL;DR: Prolonged courses of artemisinin-based combination therapies are currently efficacious in areas where standard 3-day treatments are failing, and the incidence of pretreatment and post-treatment gametocytemia was higher among patients with slow parasite clearance, suggesting greater potential for transmission.
Journal ArticleDOI
Spread of artemisinin-resistant Plasmodium falciparum in Myanmar: a cross-sectional survey of the K13 molecular marker
Kyaw Myo Tun,Mallika Imwong,Khin Maung Lwin,Aye A. Win,Tin Maung Hlaing,Thaung Hlaing,Khin Lin,Myat Phone Kyaw,Katherine Plewes,Katherine Plewes,M. Abul Faiz,Mehul Dhorda,Phaik Yeong Cheah,Phaik Yeong Cheah,Sasithon Pukrittayakamee,Elizabeth A. Ashley,Elizabeth A. Ashley,Tim J. Anderson,Shalini Nair,Marina McDew-White,Jennifer A. Flegg,Eric P. M. Grist,Philippe Allard Guérin,Richard J. Maude,Richard J. Maude,Frank Smithuis,Arjen M. Dondorp,Arjen M. Dondorp,Nicholas P. J. Day,Nicholas P. J. Day,François Nosten,Nicholas J. White,Nicholas J. White,Charles J. Woodrow,Charles J. Woodrow +34 more
TL;DR: Assessment of the spread of artemisinin-resistant P falciparum in Myanmar finds Artemisinin resistance extends across much of Myanmar, and Appropriate therapeutic regimens should be tested urgently and implemented comprehensively if spread of warfarin resistance to other regions is to be avoided.
Journal ArticleDOI
Population transcriptomics of human malaria parasites reveals the mechanism of artemisinin resistance
Sachel Mok,Elizabeth A. Ashley,Elizabeth A. Ashley,Pedro Eduardo Ferreira,Lei Zhu,Zhaoting Lin,Tomas Yeo,Kesinee Chotivanich,Mallika Imwong,Sasithon Pukrittayakamee,Mehul Dhorda,Mehul Dhorda,Mehul Dhorda,Chea Nguon,Pharath Lim,Chanaki Amaratunga,Seila Suon,Tran Tinh Hien,Ye Htut,M. Abul Faiz,Marie A. Onyamboko,Mayfong Mayxay,Mayfong Mayxay,Paul N. Newton,Paul N. Newton,Paul N. Newton,Rupam Tripura,Charles J. Woodrow,Charles J. Woodrow,Olivo Miotto,Olivo Miotto,Olivo Miotto,Dominic P. Kwiatkowski,Dominic P. Kwiatkowski,François Nosten,François Nosten,Nicholas P. J. Day,Nicholas P. J. Day,Peter R. Preiser,Nicholas J. White,Nicholas J. White,Arjen M. Dondorp,Arjen M. Dondorp,Rick M. Fairhurst,Zbynek Bozdech +44 more
TL;DR: Analysis of in vivo transcriptomes of P. falciparum isolates from patients with acute malaria found that artemisinin resistance is associated with increased expression of unfolded protein response (UPR) pathways involving the major PROSC and TRiC chaperone complexes.
Journal ArticleDOI
Two Nonrecombining Sympatric Forms of the Human Malaria Parasite Plasmodium ovale Occur Globally
Colin J. Sutherland,Naowarat Tanomsing,Debbie Nolder,Mary C. Oguike,Charlie Jennison,Sasithon Pukrittayakamee,Christiane Dolecek,Tran Tinh Hien,Virgílio E. do Rosário,Ana Paula Arez,João Pinto,Pascal Michon,Ananias A. Escalante,François Nosten,François Nosten,Martina Burke,Rogan Lee,Marie Blaze,Thomas D. Otto,John W. Barnwell,Arnab Pain,John D. Williams,Nicholas J. White,Nicholas J. White,Nicholas P. J. Day,Nicholas P. J. Day,Georges Snounou,Georges Snounou,Peter J. Lockhart,Peter L. Chiodini,Mallika Imwong,Spencer D. Polley +31 more
TL;DR: It is proposed that P. ovale comprises 2 nonrecombining species that are sympatric in Africa and Asia and speculate on possible scenarios that could have led to this speciation.
Journal ArticleDOI
Mixed-species malaria infections in humans.
Mayfong Mayxay,Mayfong Mayxay,Sasithon Pukrittayakamee,Paul N. Newton,Paul N. Newton,Nicholas J. White,Nicholas J. White,Nicholas J. White +7 more
TL;DR: In epidemiological studies, a high prevalence of cryptic mixed-malaria species infection has been detected by sensitive PCR techniques and these interactions have important clinical and public health implications.