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Takashi Saito

Researcher at Nagoya City University

Publications -  1220
Citations -  60014

Takashi Saito is an academic researcher from Nagoya City University. The author has contributed to research in topics: Medicine & MAGIC (telescope). The author has an hindex of 112, co-authored 1041 publications receiving 52937 citations. Previous affiliations of Takashi Saito include Mitsubishi Electric & Nippon Medical School.

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Journal ArticleDOI

Interferon gamma production by natural killer (NK) cells and NK1.1+ T cells upon NKR-P1 cross-linking.

TL;DR: The results indicate that NKR-P1 is a receptor molecule on NK and NK1.1+ T cells that induces not only cytotoxicity but also IFN-gamma production.
Journal Article

Human soluble IL-6 receptor: its detection and enhanced release by HIV infection.

TL;DR: The results suggest that the release of soluble IL-6R might be linked to regulatory functions of immune responses induced by IL- 6 stimulation during normal and human retrovirus-infected cell growth and differentiation.
Journal ArticleDOI

Oxidative stress by tumor-derived macrophages suppresses the expression of CD3 ζ chain of T-cell receptor complex and antigen-specific T-cell responses

TL;DR: It is demonstrated that oxidative stress by macrophages in tumor-bearing status induces abnormality of the T-cell receptor complex by cell interactions with T cells and suggests that oxidative Stress contributes to the regulation of the expression and function of theT- cell receptor complex.
Journal ArticleDOI

Failure to synthesize the T Cell CD3-ζ chain: Structure and function of a partial T cell receptor complex

TL;DR: Surprisingly, in the absence of CD3-zeta, direct cross-linking of the partial receptor induced both phosphatidylinositol hydrolysis and interleukin 2 production, which indicates that CD3/Ti determines the normal intracellular fate of the T cell antigen receptor.
MonographDOI

Science with the Cherenkov Telescope Array

B. S. Acharya, +580 more
TL;DR: The Cherenkov Telescope Array (CTA) as mentioned in this paper is the major global observatory for very high energy gamma-ray astronomy over the next decade and beyond, covering a huge range in photon energy from 20 GeV to 300 TeV.