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Ulrike Holzgrabe
Researcher at University of Würzburg
Publications - 591
Citations - 11158
Ulrike Holzgrabe is an academic researcher from University of Würzburg. The author has contributed to research in topics: Allosteric regulation & Capillary electrophoresis. The author has an hindex of 45, co-authored 566 publications receiving 9806 citations. Previous affiliations of Ulrike Holzgrabe include Jagiellonian University & University of Illinois at Chicago.
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Quantitative NMR spectroscopy in pharmaceutical applications.
TL;DR: In this article, the authors proposed a method to solve the problem of "missing links" in the context of biomedical data. But they did not specify how to find them. But
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Penetration of antibacterials into bone: pharmacokinetic, pharmacodynamic and bioanalytical considerations.
TL;DR: Established and new sample preparation and analytical methods to measure bone concentrations and the extent and rate of bone penetration of antibacterials are compared, with a focus on studies conducted between 1998 and 2007.
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Quaternary Ammonium Salts and Their Antimicrobial Potential: Targets or Nonspecific Interactions?
TL;DR: A review of the structure–activity relationships and the modes of action of the various series of mono‐ and bisquaternary ammonium compounds found to have improved antimicrobial activity against mycobacteria and protozoa.
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Quantitative NMR spectroscopy--applications in drug analysis.
TL;DR: This review gives an overview of the application of quantitative NMR spectroscopy in International Pharmacopoeias and for licensing purposes.
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Comparison of pharmacological activities of three distinct kappa ligands (Salvinorin A, TRK-820 and 3FLB) on kappa opioid receptors in vitro and their antipruritic and antinociceptive activities in vivo.
Yulin Wang,Kang Tang,Saadet Inan,Daniel J. Siebert,Ulrike Holzgrabe,David Y.W. Lee,Peng Huang,Jian-Guo Li,Alan Cowan,Lee-Yuan Liu-Chen +9 more
TL;DR: In vitro pharmacological activities on receptors expressed in Chinese hamster ovary cells and in vivo antiscratch and antinociceptive activities in mice are investigated and salvinorin A, TRK-820, and 3FLB caused internalization of the human KOR in a dose-dependent manner.