V
Vivian G. Cheung
Researcher at University of Michigan
Publications - 82
Citations - 11349
Vivian G. Cheung is an academic researcher from University of Michigan. The author has contributed to research in topics: Gene & Regulation of gene expression. The author has an hindex of 39, co-authored 74 publications receiving 10446 citations. Previous affiliations of Vivian G. Cheung include Howard Hughes Medical Institute & Children's Hospital of Philadelphia.
Papers
More filters
Journal ArticleDOI
Toxicity testing in the 21st century: a vision and a strategy
Daniel Krewski,Daniel Acosta,Melvin E. Andersen,Henry A. Anderson,John C. Bailar,Kim Boekelheide,Robert L. Brent,Gail Charnley,Vivian G. Cheung,Sidney Green,Karl T. Kelsey,Nancy I. Kerkvliet,Abby A. Li,Lawrence E. McCray,Otto A. Meyer,Reid D. Patterson,William D. Pennie,Robert A. Scala,Gina Solomon,Martin L. Stephens,James D. Yager,Lauren Zeise +21 more
TL;DR: Implementation of a new toxicity testing paradigm firmly based on human biology by transitioning from current expensive and lengthy in vivo testing with qualitative endpoints to in vitro toxicity pathway assays on human cells or cell lines using robotic high-throughput screening with mechanistic quantitative parameters.
Journal ArticleDOI
Genetic analysis of genome-wide variation in human gene expression
Michael Morley,Cliona Molony,Teresa M. Weber,Teresa M. Weber,James L. Devlin,Kathryn G. Ewens,Richard S. Spielman,Vivian G. Cheung,Vivian G. Cheung +8 more
TL;DR: This work used microarrays to measure gene expression levels and performed genome-wide linkage analysis for expression levels of 3,554 genes in 14 large families to localize the genetic determinants of these quantitative traits in humans.
Journal ArticleDOI
A physical map of the human genome.
John Douglas Mcpherson,Marco A. Marra,Marco A. Marra,LaDeana W. Hillier,Robert H. Waterston,Asif T. Chinwalla,John W. Wallis,Mandeep Sekhon,Kristine M. Wylie,Elaine R. Mardis,Richard K. Wilson,Robert S. Fulton,Tamara A. Kucaba,Caryn Wagner-McPherson,William B. Barbazuk,Simon G. Gregory,Sean Humphray,Lisa French,R Evans,Graeme Bethel,Adam Whittaker,Jane L. Holden,Owen T. McCann,Andrew Dunham,Carol Soderlund,Carol Scott,David R. Bentley,Gregory D. Schuler,Hsiu Chuan Chen,Wonhee Jang,Eric D. Green,Jacquelyn R. Idol,Valerie Maduro,Kate Montgomery,Eunice Lee,Ashley Miller,Suzanne Emerling,Raju Kucherlapati,Richard A. Gibbs,Steve Scherer,J. Harley Gorrell,Erica Sodergren,Kerstin P. Clerc-Blankenburg,Paul E. Tabor,S. Naylor,Dawn Garcia,J. de Jong,J. de Jong,J. de Jong,Joseph J. Catanese,Joseph J. Catanese,Joseph J. Catanese,Norma J. Nowak,Kazutoyo Osoegawa,Kazutoyo Osoegawa,Kazutoyo Osoegawa,Shizhen Qin,Lee Rowen,Anuradha Madan,Monica Dors,Leroy Hood,Barbara J. Trask,Cynthia Friedman,Hillary Massa,Vivian G. Cheung,Ilan R. Kirsch,Thomas Reid,Raluca Yonescu,Jean Weissenbach,Thomas Brüls,Roland Heilig,Elbert Branscomb,Anne S. Olsen,Norman A. Doggett,Jan Fang Cheng,Trevor Hawkins,Richard M. Myers,Jin Shang,Lucía Ramírez,Jeremy Schmutz,Olivia Velasquez,Kami Dixon,Nancy E. Stone,David R. Cox,David Haussler,W. James Kent,Terrence S. Furey,Sanja Rogic,Scot Kennedy,Steven J.M. Jones,André Rosenthal,Gaiping Wen,Markus Schilhabel,Gernot Gloeckner,Gerald Nyakatura,Reiner Siebert,Brigitte Schlegelberger,Julie R. Korenberg,Xiao Ning Chen,Asao Fujiyama,Masahira Hattori,Atsushi Toyoda,Tetsushi Yada,Hong Seok Park,Yoshiyuki Sakaki,Nobuyoshi Shimizu,Shuichi Asakawa,Kazuhiko Kawasaki,Takashi Sasaki,Ai Shintani,Atsushi Shimizu,Kazunori Shibuya,Jun Kudoh,Shinsei Minoshima,Juliane Ramser,Peter Seranski,Céline Hoff,Annemarie Poustka,Richard Reinhardt,Hans Lehrach +119 more
TL;DR: The construction of the whole-genome bacterial artificial chromosome (BAC) map and its integration with previous landmark maps and information from mapping efforts focused on specific chromosomal regions are reported.
Journal ArticleDOI
Making and reading microarrays
Vivian G. Cheung,Michael Morley,Francisco Aguilar,Aldo Massimi,Raju Kucherlapati,Geoffrey Childs +5 more
TL;DR: The building and use of two microarray facilities in academic settings are described and the advantages and disadvantages of components and approaches are commented on, and a protocol for hybridization is provided.
Journal ArticleDOI
Natural variation in human gene expression assessed in lymphoblastoid cells
Vivian G. Cheung,Laura K. Conlin,Teresa M. Weber,Melissa Arcaro,Kuang-Yu Jen,Michael Morley,Richard S. Spielman +6 more
TL;DR: There is evidence for familial aggregation of expression phenotype by comparing variation among unrelated individuals, among siblings within families and between monozygotic twins, which suggests that there is a genetic contribution to polymorphic variation in the level of gene expression.