Institution
Centers for Disease Control and Prevention
Government•Atlanta, Georgia, United States•
About: Centers for Disease Control and Prevention is a government organization based out in Atlanta, Georgia, United States. It is known for research contribution in the topics: Population & Public health. The organization has 58238 authors who have published 82592 publications receiving 4405701 citations. The organization is also known as: CDC & Centers for Disease Control and Prevention (CDC).
Topics: Population, Public health, Vaccination, Poison control, Acquired immunodeficiency syndrome (AIDS)
Papers published on a yearly basis
Papers
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TL;DR: Vancomycin-resistant S. aureus was cultured from the exit site of a temporary dialysis catheter of a patient with diabetes, peripheral vascular disease, and persistent foot ulcers and carried the vanA resistance gene, which may have come from the vancomycius-resistant Enterococcus faecalis that was also isolated from the patient.
Abstract: Vancomycin-resistant S. aureus was cultured from the exit site of a temporary dialysis catheter of a patient with diabetes, peripheral vascular disease, and persistent foot ulcers. The organism carried the vanA resistance gene, which may have come from the vancomycin-resistant Enterococcus faecalis that was also isolated from the patient, who had received vancomycin for several weeks.
1,114 citations
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TL;DR: DNA priming followed by a recombinant modified vaccinia Ankara (rMVA) booster controlled a highly pathogenic immunodeficiency virus challenge in a rhesus macaque model, providing hope that a relatively simple multiprotein DNA/MVA vaccine can help to control the acquired immune deficiency syndrome epidemic.
Abstract: Heterologous prime/boost regimens have the potential for raising high levels of immune responses. Here we report that DNA priming followed by a recombinant modified vaccinia Ankara (rMVA) booster controlled a highly pathogenic immunodeficiency virus challenge in a rhesus macaque model. Both the DNA and rMVA components of the vaccine expressed multiple immunodeficiency virus proteins. Two DNA inoculations at 0 and 8 weeks and a single rMVA booster at 24 weeks effectively controlled an intrarectal challenge administered 7 months after the booster. These findings provide hope that a relatively simple multiprotein DNA/MVA vaccine can help to control the acquired immune deficiency syndrome epidemic.
1,114 citations
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TL;DR: Passeriform and charadriiform birds were more reservoir competent (a derivation of viremia data) than other species tested and Persistent WNV infections were found in tissues of 16 surviving birds.
Abstract: To evaluate transmission dynamics, we exposed 25 bird species to West Nile virus (WNV) by infectious mosquito bite. We monitored viremia titers, clinical outcome, WNV shedding (cloacal and oral), seroconversion, virus persistence in organs, and susceptibility to oral and contact transmission. Passeriform and charadriiform birds were more reservoir competent (a derivation of viremia data) than other species tested. The five most competent species were passerines: Blue Jay (Cyanocitta cristata), Common Grackle (Quiscalus quiscula), House Finch (Carpodacus mexicanus), American Crow (Corvus brachyrhynchos), and House Sparrow (Passer domesticus). Death occurred in eight species. Cloacal shedding of WNV was observed in 17 of 24 species, and oral shedding in 12 of 14 species. We observed contact transmission among four species and oral in five species. Persistent WNV infections were found in tissues of 16 surviving birds. Our observations shed light on transmission ecology of WNV and will benefit surveillance and control programs.
1,113 citations
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TL;DR: This paper aims to identify studies which were relevant to one or more key questions and which were primary analytic research, systematic review or meta-analysis and written in English.
Abstract: AND FULL-TEXT SCREENING To identify studies which were a) relevant to one or more key questions b) primary analytic research, systematic review or meta-analysis and c) written in English DATA EXTRACTION AND SYNTHESIS Data abstracted into evidence tables; study quality assessed DRAFT RECOMMENDATIONS Strength of evidence graded; summaries and recommendations drafted FINALIZE RECOMMENDATIONS Recommendations finalized; guideline published
1,109 citations
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TL;DR: Primary prevention of adverse childhood experiences and improved treatment of exposed children could reduce smoking among both adolescents and adults.
Abstract: ContextIn recent years, smoking among adolescents has increased and the decline
of adult smoking has slowed to nearly a halt; new insights into tobacco dependency
are needed to correct this situation. Long-term use of nicotine has been linked
with self-medicating efforts to cope with negative emotional, neurobiological,
and social effects of adverse childhood experiences.ObjectiveTo assess the relationship between adverse childhood experiences and
5 smoking behaviors.DesignThe ACE Study, a retrospective cohort survey including smoking and exposure
to 8 categories of adverse childhood experiences (emotional, physical, and
sexual abuse; a battered mother; parental separation or divorce; and growing
up with a substance-abusing, mentally ill, or incarcerated household member),
conducted from August to November 1995 and January to March 1996.SettingA primary care clinic for adult members of a large health maintenance
organization in San Diego, Calif.ParticipantsA total of 9215 adults (4958 women and 4257 men with mean [SD] ages
of 55.3 [15.7] and 58.1 [14.5] years, respectively) who responded to a survey
questionnaire, which was mailed to all patients 1 week after a clinic visit.Main Outcome MeasuresSmoking initiation by age 14 years or after age 18 years, and status
as ever, current, or heavy smoker.ResultsAt least 1 of 8 categories of adverse childhood experiences was reported
by 63% of respondents. After adjusting for age, sex, race, and education,
each category showed an increased risk for each smoking behavior, and these
risks were comparable for each category of adverse childhood experiences.
Compared with those reporting no adverse childhood experiences, persons reporting
5 or more categories had substantially higher risks of early smoking initiation
(odds ratio [OR], 5.4; 95% confidence interval [CI], 4.1-7.1), ever smoking
(OR, 3.1; 95% CI, 2.6-3.8), current smoking (OR, 2.1; 95% CI, 1.6-2.7), and
heavy smoking (OR, 2.8; 95% CI, 1.9-4.2). Each relationship between smoking
behavior and the number of adverse childhood experiences was strong and graded
(P<.001). For any given number of adverse childhood
experiences, recent problems with depressed affect were more common among
smokers than among nonsmokers.ConclusionsSmoking was strongly associated with adverse childhood experiences.
Primary prevention of adverse childhood experiences and improved treatment
of exposed children could reduce smoking among both adolescents and adults.
1,108 citations
Authors
Showing all 58382 results
Name | H-index | Papers | Citations |
---|---|---|---|
Graham A. Colditz | 261 | 1542 | 256034 |
David J. Hunter | 213 | 1836 | 207050 |
Bernard Rosner | 190 | 1162 | 147661 |
Richard Peto | 183 | 683 | 231434 |
Aaron R. Folsom | 181 | 1118 | 134044 |
Didier Raoult | 173 | 3267 | 153016 |
James F. Sallis | 169 | 825 | 144836 |
David R. Jacobs | 165 | 1262 | 113892 |
Steven N. Blair | 165 | 879 | 132929 |
Gordon J. Freeman | 164 | 579 | 105193 |
Dennis R. Burton | 164 | 683 | 90959 |
Rory Collins | 162 | 489 | 193407 |
Ali H. Mokdad | 156 | 634 | 160599 |
Caroline S. Fox | 155 | 599 | 138951 |
Paul Elliott | 153 | 773 | 103839 |