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Institution

Durham University

EducationDurham, United Kingdom
About: Durham University is a education organization based out in Durham, United Kingdom. It is known for research contribution in the topics: Population & Galaxy. The organization has 39385 authors who have published 82311 publications receiving 3110994 citations. The organization is also known as: University of Durham & Gallery of Durham University.


Papers
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Journal ArticleDOI
TL;DR: The state of the art in condition monitoring for power electronics can be found in this paper, where the authors present a review of the current state-of-the-art in power electronics condition monitoring.
Abstract: Condition monitoring (CM) has already been proven to be a cost effective means of enhancing reliability and improving customer service in power equipment, such as transformers and rotating electrical machinery. CM for power semiconductor devices in power electronic converters is at a more embryonic stage; however, as progress is made in understanding semiconductor device failure modes, appropriate sensor technologies, and signal processing techniques, this situation will rapidly improve. This technical review is carried out with the aim of describing the current state of the art in CM research for power electronics. Reliability models for power electronics, including dominant failure mechanisms of devices are described first. This is followed by a description of recently proposed CM techniques. The benefits and limitations of these techniques are then discussed. It is intended that this review will provide the basis for future developments in power electronics CM.

820 citations

Journal ArticleDOI
TL;DR: The soluble glutathione transferases (GSTs) represent an excellent example of how protein families can diversify to fulfill multiple functions while conserving form and structure.
Abstract: The soluble glutathione transferases (GSTs, EC 2.5.1.18) are encoded by a large and diverse gene family in plants, which can be divided on the basis of sequence identity into the phi, tau, theta, zeta and lambda classes. The theta and zeta GSTs have counterparts in animals but the other classes are plant-specific and form the focus of this article. The genome of Arabidopsis thaliana contains 48 GST genes, with the tau and phi classes being the most numerous. The GST proteins have evolved by gene duplication to perform a range of functional roles using the tripeptide glutathione (GSH) as a cosubstrate or coenzyme. GSTs are predominantly expressed in the cytosol, where their GSH-dependent catalytic functions include the conjugation and resulting detoxification of herbicides, the reduction of organic hydroperoxides formed during oxidative stress and the isomerization of maleylacetoacetate to fumarylacetoacetate, a key step in the catabolism of tyrosine. GSTs also have non-catalytic roles, binding flavonoid natural products in the cytosol prior to their deposition in the vacuole. Recent studies have also implicated GSTs as components of ultraviolet-inducible cell signaling pathways and as potential regulators of apoptosis. Although sequence diversification has produced GSTs with multiple functions, the structure of these proteins has been highly conserved. The GSTs thus represent an excellent example of how protein families can diversify to fulfill multiple functions while conserving form and structure.

820 citations

Journal ArticleDOI
TL;DR: In this article, the authors present empirical studies to guide researchers in determining the number of focus groups necessary for a research study, and the analyses described here provide foundational evidence to help research.
Abstract: Few empirical studies exist to guide researchers in determining the number of focus groups necessary for a research study. The analyses described here provide foundational evidence to help research...

819 citations

Journal ArticleDOI
01 Sep 2007-Geology
TL;DR: In this article, amphibole is used as a filter for water dissolved in mantle-derived arc magmas, and amphibole cumulates may act as a fertile source of intracrustal melts and fluids.
Abstract: Pressure-temperature-time paths followed by arc magmas ascending through the lithosphere dictate the phase assemblage that crystallizes, and hence the compositions of liquid fractionates. Here we use La/Yb and Dy/Yb versus SiO2 relationships from selected volcanoes to show that amphibole is an important mineral during differentiation of arc magma. Production of intermediate and silicic arc magmas occurs as magmas stall and cool in the mid-lower crust, where amphibole is stable. Because amphibole is rarely a phenocryst phase, we term this “cryptic amphibole fractionation.” If this process is as widespread as our investigation suggests, then (1) amphibole cumulates may act as an effective filter for water dissolved in mantle-derived magmas; (2) amphibole cumulates may act as a fertile source of intracrustal melts and fluids; and (3) recycling of amphibole cumulates has the potential to return incompatible trace elements and water to the mantle.

819 citations

Proceedings ArticleDOI
12 Jan 2003
TL;DR: A novel implementation of compressed suffix arrays exhibiting new tradeoffs between search time and space occupancy for a given text (or sequence) of n symbols over an alphabet σ, where each symbol is encoded by lg|σ| bits.
Abstract: We present a novel implementation of compressed suffix arrays exhibiting new tradeoffs between search time and space occupancy for a given text (or sequence) of n symbols over an alphabet σ, where each symbol is encoded by lgvσv bits. We show that compressed suffix arrays use just nHh + σ bits, while retaining full text indexing functionalities, such as searching any pattern sequence of length m in O(m lg vσv + polylog(n)) time. The term Hh ≤ lg vσv denotes the hth-order empirical entropy of the text, which means that our index is nearly optimal in space apart from lower-order terms, achieving asymptotically the empirical entropy of the text (with a multiplicative constant 1). If the text is highly compressible so that Hn = o(1) and the alphabet size is small, we obtain a text index with o(m) search time that requires only o(n) bits. Further results and tradeoffs are reported in the paper.

818 citations


Authors

Showing all 39730 results

NameH-indexPapersCitations
Eugene Braunwald2301711264576
Robert J. Lefkowitz214860147995
David J. Hunter2131836207050
Francis S. Collins196743250787
Robert M. Califf1961561167961
Martin White1962038232387
Eric J. Topol1931373151025
David J. Schlegel193600193972
Simon D. M. White189795231645
George Efstathiou187637156228
Terrie E. Moffitt182594150609
John A. Rogers1771341127390
Avshalom Caspi170524113583
Richard S. Ellis169882136011
Rob Ivison1661161102314
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Performance
Metrics
No. of papers from the Institution in previous years
YearPapers
2023182
2022555
20214,695
20204,628
20194,239
20184,047