Durham University

About: Durham University is a education organization based out in Durham, United Kingdom. It is known for research contribution in the topics: Population & Galaxy. The organization has 39385 authors who have published 82311 publications receiving 3110994 citations. The organization is also known as: University of Durham & Gallery of Durham University.

The Masses of Nuclear Black Holes in Luminous Elliptical Galaxies and Implications for the Space Density of the Most Massive Black Holes

Abstract: Black hole (BH) masses predicted from the M•-σ relationship conflict with predictions from the M•-L relationship for high-luminosity galaxies, such as brightest cluster galaxies (BCGs). The M•-L relationship predicts that some BCGs may harbor BHs with M• approaching 1010 M☉, while the M•-σ relationship always predicts M• 3 × 109 M☉ would be nearly an order of magnitude richer than that inferred from the M•-σ relationship. The volume density of the most luminous QSOs may favor the M•-L relationship.

The cognitive and behavioral characteristics of children with low working memory.

Abstract: This study explored the cognitive and behavioral profiles of children with working memory impairments. In an initial screening of 3,189 five- to eleven-year-olds, 308 were identified as having very low working memory scores. Cognitive skills (IQ, vocabulary, reading, and math), classroom behavior, and self-esteem were assessed. The majority of the children struggled in the learning measures and verbal ability. They also obtained atypically high ratings of cognitive problems/inattentive symptoms and were judged to have short attention spans, high levels of distractibility, problems in monitoring the quality of their work, and difficulties in generating new solutions to problems. These data provide rich new information on the cognitive and behavioral profiles that characterize children with low working memory.

Reliability analysis for wind turbines

Abstract: Modern wind turbines are complex aerodynamic, mechanical and electrical machines incorporating sophisticated control systems. Wind turbines have been erected in increasing numbers in Europe, the USA and elsewhere. In Europe, Germany and Denmark have played a particularly prominent part in developing the technology, and both countries have installed large numbers of turbines. This article is concerned with understanding the historic reliability of modern wind turbines. The prime objective of the work is to extract information from existing data so that the reliability of large wind turbines can be predicted, particularly when installed offshore in the future. The article uses data collected from the Windstats survey to analyse the reliability of wind turbine components from historic German and Danish data. Windstats data have characteristics common to practical reliability surveys; for example, the number of failures is collected for each interval but the number of turbines varies in each interval. In this article, the authors use reliability analysis methods which are not only applicable to wind turbines but relate to any repairable system. Particular care is taken to compare results from the two populations to consider the validity of the data. The main purpose of the article is to discuss the practical methods of predicting large-wind-turbine reliability using grouped survey data from Windstats and to show how turbine design, turbine configuration, time, weather and possibly maintenance can affect the extracted results. Copyright © 2006 John Wiley &Sons, Ltd.

Benefits and Harms of Breast Cancer Screening: A Systematic Review

Abstract: Importance Patients need to consider both benefits and harms of breast cancer screening. Objective To systematically synthesize available evidence on the association of mammographic screening and clinical breast examination (CBE) at different ages and intervals with breast cancer mortality, overdiagnosis, false-positive biopsy findings, life expectancy, and quality-adjusted life expectancy. Evidence Review We searched PubMed (to March 6, 2014), CINAHL (to September 10, 2013), and PsycINFO (to September 10, 2013) for systematic reviews, randomized clinical trials (RCTs) (with no limit to publication date), and observational and modeling studies published after January 1, 2000, as well as systematic reviews of all study designs. Included studies (7 reviews, 10 RCTs, 72 observational, 1 modeling) provided evidence on the association between screening with mammography, CBE, or both and prespecified critical outcomes among women at average risk of breast cancer (no known genetic susceptibility, family history, previous breast neoplasia, or chest irradiation). We used summary estimates from existing reviews, supplemented by qualitative synthesis of studies not included in those reviews. Findings Across all ages of women at average risk, pooled estimates of association between mammography screening and mortality reduction after 13 years of follow-up were similar for 3 meta-analyses of clinical trials (UK Independent Panel: relative risk [RR], 0.80 [95% CI, 0.73-0.89]; Canadian Task Force: RR, 0.82 [95% CI, 0.74-0.94]; Cochrane: RR, 0.81 [95% CI, 0.74-0.87]); were greater in a meta-analysis of cohort studies (RR, 0.75 [95% CI, 0.69 to 0.81]); and were comparable in a modeling study (CISNET; median RR equivalent among 7 models, 0.85 [range, 0.77-0.93]). Uncertainty remains about the magnitude of associated mortality reduction in the entire US population, among women 40 to 49 years, and with annual screening compared with biennial screening. There is uncertainty about the magnitude of overdiagnosis associated with different screening strategies, attributable in part to lack of consensus on methods of estimation and the importance of ductal carcinoma in situ in overdiagnosis. For women with a first mammography screening at age 40 years, estimated 10-year cumulative risk of a false-positive biopsy result was higher (7.0% [95% CI, 6.1%-7.8%]) for annual compared with biennial (4.8% [95% CI, 4.4%-5.2%]) screening. Although 10-year probabilities of false-positive biopsy results were similar for women beginning screening at age 50 years, indirect estimates of lifetime probability of false-positive results were lower. Evidence for the relationship between screening and life expectancy and quality-adjusted life expectancy was low in quality. There was no direct evidence for any additional mortality benefit associated with the addition of CBE to mammography, but observational evidence from the United States and Canada suggested an increase in false-positive findings compared with mammography alone, with both studies finding an estimated 55 additional false-positive findings per extra breast cancer detected with the addition of CBE. Conclusions and Relevance For women of all ages at average risk, screening was associated with a reduction in breast cancer mortality of approximately 20%, although there was uncertainty about quantitative estimates of outcomes for different breast cancer screening strategies in the United States. These findings and the related uncertainty should be considered when making recommendations based on judgments about the balance of benefits and harms of breast cancer screening.