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Showing papers by "École Polytechnique published in 2005"


Journal ArticleDOI
TL;DR: Theoretical and phenomenological implications of R-parity violation in supersymmetric theories are discussed in the context of particle physics and cosmology in this paper, including the relation with continuous and discrete symmetries.

949 citations


Journal ArticleDOI
TL;DR: A new class of bases are introduced, called bandelet bases, which decompose the image along multiscale vectors that are elongated in the direction of a geometric flow, which leads to optimal approximation rates for geometrically regular images.
Abstract: This paper introduces a new class of bases, called bandelet bases, which decompose the image along multiscale vectors that are elongated in the direction of a geometric flow. This geometric flow indicates directions in which the image gray levels have regular variations. The image decomposition in a bandelet basis is implemented with a fast subband-filtering algorithm. Bandelet bases lead to optimal approximation rates for geometrically regular images. For image compression and noise removal applications, the geometric flow is optimized with fast algorithms so that the resulting bandelet basis produces minimum distortion. Comparisons are made with wavelet image compression and noise-removal algorithms.

922 citations


Book ChapterDOI
01 Jan 2005
TL;DR: In most vehicle routing and crew scheduling applications solved by column generation, the subproblem corresponds to a shortest path problem with resource constraints (SPPRC) or one of its variants.
Abstract: In most vehicle routing and crew scheduling applications solved by column generation, the subproblem corresponds to a shortest path problem with resource constraints (SPPRC) or one of its variants.

654 citations


Proceedings ArticleDOI
20 Jun 2005
TL;DR: The segmentation algorithm works simultaneously across the graph scales, with an inter-scale constraint to ensure communication and consistency between the segmentations at each scale, and incorporates long-range connections with linear-time complexity, providing high-quality segmentations efficiently.
Abstract: We present a multiscale spectral image segmentation algorithm. In contrast to most multiscale image processing, this algorithm works on multiple scales of the image in parallel, without iteration, to capture both coarse and fine level details. The algorithm is computationally efficient, allowing to segment large images. We use the normalized cut graph partitioning framework of image segmentation. We construct a graph encoding pairwise pixel affinity, and partition the graph for image segmentation. We demonstrate that large image graphs can be compressed into multiple scales capturing image structure at increasingly large neighborhood. We show that the decomposition of the image segmentation graph into different scales can be determined by ecological statistics on the image grouping cues. Our segmentation algorithm works simultaneously across the graph scales, with an inter-scale constraint to ensure communication and consistency between the segmentations at each scale. As the results show, we incorporate long-range connections with linear-time complexity, providing high-quality segmentations efficiently. Images that previously could not be processed because of their size have been accurately segmented thanks to this method.

635 citations


Journal ArticleDOI
TL;DR: These new air-stable complexes using the bis(trifluoromethanesulfonyl)imidate moiety as a weakly coordinating counter-anion are described and are exceedingly active for the catalysis of a wide range of enynes cycloisomerizations.

594 citations


Journal ArticleDOI
TL;DR: It is found that VO2 is not a conventional Mott insulator, but that the formation of dynamical V-V singlet pairs due to strong Coulomb correlations is necessary to trigger the opening of a Peierls gap.
Abstract: A theory of the metal-insulator transition in vanadium dioxide from the high- temperature rutile to the low- temperature monoclinic phase is proposed on the basis of cluster dynamical mean-field theory, in conjunction with the density functional scheme. The interplay of strong electronic Coulomb interactions and structural distortions, in particular, the dimerization of vanadium atoms in the low-temperature phase, plays a crucial role. We find that ${\mathrm{V}\mathrm{O}}_{2}$ is not a conventional Mott insulator, but that the formation of dynamical V-V singlet pairs due to strong Coulomb correlations is necessary to trigger the opening of a Peierls gap.

586 citations


Journal ArticleDOI
TL;DR: This software, implemented as a Java plug-in for the public-domain ImageJ software, is used to track the movement of chromosomal loci within nuclei of budding yeast cells to reveal different classes of constraints on mobility of telomeres, reflecting differences in nuclear envelope association.
Abstract: We present a new, robust, computational procedure for tracking fluorescent markers in time-lapse microscopy. The algorithm is optimized for finding the time-trajectory of single particles in very noisy dynamic (two- or three-dimensional) image sequences. It proceeds in three steps. First, the images are aligned to compensate for the movement of the biological structure under investigation. Second, the particle's signature is enhanced by applying a Mexican hat filter, which we show to be the optimal detector of a Gaussian-like spot in 1//spl omega//sup 2/ noise. Finally, the optimal trajectory of the particle is extracted by applying a dynamic programming optimization procedure. We have used this software, which is implemented as a Java plug-in for the public-domain ImageJ software, to track the movement of chromosomal loci within nuclei of budding yeast cells. Besides reducing trajectory analysis time by several 100-fold, we achieve high reproducibility and accuracy of tracking. The application of the method to yeast chromatin dynamics reveals different classes of constraints on mobility of telomeres, reflecting differences in nuclear envelope association. The generic nature of the software allows application to a variety of similar biological imaging tasks that require the extraction and quantitation of a moving particle's trajectory.

463 citations


Journal ArticleDOI
TL;DR: In this paper, the authors characterize = 1 vacua of type-II theories in terms of generalized complex structure on the internal manifold M. The conditions for preserving = 1 supersymmetry turn out to be simple generalizations of equations that have appeared in the context of = 2 and topological strings.
Abstract: We characterize = 1 vacua of type-II theories in terms of generalized complex structure on the internal manifold M. The structure group of T(M)⊕T*(M) being SU(3) × SU(3) implies the existence of two pure spinors Φ1 and Φ2. The conditions for preserving = 1 supersymmetry turn out to be simple generalizations of equations that have appeared in the context of = 2 and topological strings. They are (d+H∧)Φ1 = 0 and (d+H∧)Φ2 = FRR. The equation for the first pure spinor implies that the internal space is a twisted generalized Calabi-Yau manifold of a hybrid complex-symplectic type, while the RR-fields serve as an integrability defect for the second.

451 citations


Journal ArticleDOI
TL;DR: In this paper, a review is devoted to some inverse problems arising in the context of linear elasticity, namely the identification of distributions of elastic moduli, model parameters or buried objects such as cracks.
Abstract: This review is devoted to some inverse problems arising in the context of linear elasticity, namely the identification of distributions of elastic moduli, model parameters or buried objects such as cracks. These inverse problems are considered mainly for three-dimensional elastic media under equilibrium or dynamical conditions, and also for thin elastic plates. The main goal is to overview some recent results, in an effort to bridge the gap between studies of a mathematical nature and problems defined from engineering practice. Accordingly, emphasis is given to formulations and solution techniques which are well suited to general-purpose numerical methods for solving elasticity problems on complex configurations, in particular the finite element method and the boundary element method. An underlying thread of the discussion is the fact that useful tools for the formulation, analysis and solution of inverse problems arising in linear elasticity, namely the reciprocity gap and the error in constitutive equation, stem from variational and virtual work principles, i.e., fundamental principles governing the mechanics of deformable solid continua. In addition, the virtual work principle is shown to be instrumental for establishing computationally efficient formulae for parameter or geometrical sensitivity, based on the adjoint solution method. Sensitivity formulae are presented for various situations, especially in connection with contact mechanics, cavity and crack shape perturbations, thus enriching the already extensive known repertoire of such results. Finally, the concept of topological derivative and its implementation for the identification of cavities or inclusions are expounded.

411 citations


Journal ArticleDOI
TL;DR: A symmetric formulation is proposed, which combines single- and double-layer potentials, and which is new to the field of EEG, although it has been applied to other problems in electromagnetism.
Abstract: The forward electroencephalography (EEG) problem involves finding a potential V from the Poisson equation /spl nabla//spl middot/(/spl sigma//spl nabla/V)=f, in which f represents electrical sources in the brain, and /spl sigma/ the conductivity of the head tissues. In the piecewise constant conductivity head model, this can be accomplished by the boundary element method (BEM) using a suitable integral formulation. Most previous work uses the same integral formulation, corresponding to a double-layer potential. We present a conceptual framework based on a well-known theorem (Theorem 1) that characterizes harmonic functions defined on the complement of a bounded smooth surface. This theorem says that such harmonic functions are completely defined by their values and those of their normal derivatives on this surface. It allows us to cast the previous BEM approaches in a unified setting and to develop two new approaches corresponding to different ways of exploiting the same theorem. Specifically, we first present a dual approach which involves a single-layer potential. Then, we propose a symmetric formulation, which combines single- and double-layer potentials, and which is new to the field of EEG, although it has been applied to other problems in electromagnetism. The three methods have been evaluated numerically using a spherical geometry with known analytical solution, and the symmetric formulation achieves a significantly higher accuracy than the alternative methods. Additionally, we present results with realistically shaped meshes. Beside providing a better understanding of the foundations of BEM methods, our approach appears to lead also to more efficient algorithms.

392 citations


Journal Article
TL;DR: A numerical coupling of two recent methods in shape and topology optimization of structures yields an efficient algorithm which can escape from local minima in a given topological class of shapes.
Abstract: A numerical coupling of two recent methods in shape and topology optimization of structures is proposed. On the one hand, the level set method, based on the classical shape derivative, is known to easily handle boundary propagation with topological changes. However, in practice it does not allow for the nucleation of new holes (at least in 2-d). On the other hand, the bubble or topological gradient method is precisely designed for introducing new holes in the optimization process. Therefore, the coupling of these two method yields an efficient algorithm which can escape from local minima in a given topological class of shapes. Both methods relies on a notion of gradient computed through an adjoint analysis, and have a low CPU cost since they capture a shape on a fixed Eulerian mesh. The main advantage of our coupled algorithm is to make the resulting optimal design largely independent of the initial guess.

Journal ArticleDOI
TL;DR: This paper investigated whether spillovers occur via worker mobility and found that firms which are run by owners who worked for multinationals in the same industry immediately prior to opening up their own firm are more productive than other domestic firms.
Abstract: While there is a large empirical literature on productivity spillovers from multinationals, this literature treats the channels through which these spillover effects work as a black box. The new approach in this paper is to investigate whether spillovers occur via worker mobility. We use data on whether or not the owner of a domestic firm has previous experience in a multinational, and relate this information to firm-level productivity. Our results suggest that firms which are run by owners who worked for multinationals in the same industry immediately prior to opening up their own firm are more productive than other domestic firms.

Journal ArticleDOI
TL;DR: A validation study on statistical nonsupervised brain tissue classification techniques in magnetic resonance (MR) images demonstrates that methods relying on both intensity and spatial information are more robust to noise and field inhomogeneities and shows that simulated data results can be extended to real data.
Abstract: This paper presents a validation study on statistical nonsupervised brain tissue classification techniques in magnetic resonance (MR) images. Several image models assuming different hypotheses regarding the intensity distribution model, the spatial model and the number of classes are assessed. The methods are tested on simulated data for which the classification ground truth is known. Different noise and intensity nonuniformities are added to simulate real imaging conditions. No enhancement of the image quality is considered either before or during the classification process. This way, the accuracy of the methods and their robustness against image artifacts are tested. Classification is also performed on real data where a quantitative validation compares the methods' results with an estimated ground truth from manual segmentations by experts. Validity of the various classification methods in the labeling of the image as well as in the tissue volume is estimated with different local and global measures. Results demonstrate that methods relying on both intensity and spatial information are more robust to noise and field inhomogeneities. We also demonstrate that partial volume is not perfectly modeled, even though methods that account for mixture classes outperform methods that only consider pure Gaussian classes. Finally, we show that simulated data results can also be extended to real data.

Journal ArticleDOI
Felix Aharonian1, A. G. Akhperjanian2, Klaus-Michael Aye3, A. R. Bazer-Bachi4, M. Beilicke5, Wystan Benbow1, David Berge1, P. Berghaus6, Konrad Bernlöhr7, Konrad Bernlöhr1, Catherine Boisson6, O. Bolz1, V. Borrel4, Ilana M. Braun1, F. Breitling7, A. M. Brown3, J. Bussons Gordo8, P. M. Chadwick3, L.-M. Chounet9, R. Cornils5, Luigi Costamante1, B. Degrange9, Hugh Dickinson3, A. Djannati-Ataï6, L. O'c. Drury10, Guillaume Dubus9, Dimitrios Emmanoulopoulos, P. Espigat6, F. Feinstein8, P. Fleury9, G. Fontaine9, Y. Fuchs11, Stefan Funk1, Y. A. Gallant8, B. Giebels9, Stefan Gillessen1, J.F. Glicenstein12, P. Goret12, C. Hadjichristidis3, M. Hauser, G. Heinzelmann5, Gilles Henri11, German Hermann1, Jim Hinton1, Werner Hofmann1, M. Holleran13, Dieter Horns1, A. Jacholkowska8, O. C. de Jager13, B. Khélifi1, Nu. Komin7, A. Konopelko1, A. Konopelko7, I. J. Latham3, R. Le Gallou3, A. Lemiere6, M. Lemoine-Goumard9, N. Leroy9, Thomas Lohse7, A. Marcowith4, J.-M. Martin6, O. Martineau-Huynh6, Conor Masterson1, T. J. L. McComb3, M. de Naurois6, S. J. Nolan3, A. Noutsos3, K. J. Orford3, J. L. Osborne3, M. Ouchrif6, M. Panter1, Guy Pelletier11, S. Pita6, G. Pühlhofer1, Michael Punch6, B. C. Raubenheimer13, M. Raue5, J. Raux6, S. M. Rayner3, A. Reimer14, Olaf Reimer14, J. Ripken5, L. Rob15, L. Rolland6, Gavin Rowell1, V. Sahakian2, L. Saugé11, S. Schlenker7, Reinhard Schlickeiser14, C. Schuster14, U. Schwanke7, M. Siewert14, Helene Sol6, D. Spangler3, R. Steenkamp16, C. Stegmann7, J.-P. Tavernet6, Regis Terrier6, C. G. Théoret6, M. Tluczykont9, G. Vasileiadis8, Christo Venter13, P. Vincent6, Heinrich J. Völk1, Stefan Wagner 
29 Jul 2005-Science
TL;DR: Evidence for gamma-ray emission of >100 gigaelectron volts from a candidate microquasar, LS 5039, is found, showing that particles are also accelerated to very high energies in these systems.
Abstract: X-ray binaries are composed of a normal star in orbit around a neutron star or stellar-mass black hole. Radio and x-ray observations have led to the presumption that some x-ray binaries called microquasars behave as scaled-down active galactic nuclei. Microquasars have resolved radio emission that is thought to arise from a relativistic outflow akin to active galactic nuclei jets, in which particles can be accelerated to large energies. Very high energy γ-rays produced by the interactions of these particles have been observed from several active galactic nuclei. Using the High Energy Stereoscopic System, we find evidence for gamma-ray emission of >100 gigaelectron volts from a candidate microquasar, LS 5039, showing that particles are also accelerated to very high energies in these systems.

Book ChapterDOI
09 Nov 2005
TL;DR: It is shown that solutions to binary MRFs can be found by minimizing an appropriate ROF problem, and vice-versa, which leads to new algorithms.
Abstract: We observe that there is a strong connection between a whole class of simple binary MRF energies and the Rudin-Osher-Fatemi (ROF) Total Variation minimization approach to image denoising. We show, more precisely, that solutions to binary MRFs can be found by minimizing an appropriate ROF problem, and vice-versa. This leads to new algorithms. We then compare the efficiency of various algorithms.

Journal ArticleDOI
Felix Aharonian1, A. G. Akhperjanian2, Klaus-Michael Aye3, A. R. Bazer-Bachi4, M. Beilicke5, Wystan Benbow1, David Berge1, P. Berghaus, Konrad Bernlöhr1, Konrad Bernlöhr6, Catherine Boisson4, O. Bolz1, Ilana M. Braun1, F. Breitling6, A. M. Brown3, J. Bussons Gordo7, P. M. Chadwick3, L.-M. Chounet8, R. Cornils5, Luigi Costamante1, Luigi Costamante4, B. Degrange8, A. Djannati-Ataï, L. O'c. Drury9, Guillaume Dubus8, Dimitrios Emmanoulopoulos, P. Espigat, F. Feinstein7, P. Fleury8, G. Fontaine8, Y. Fuchs10, Seb. Funk1, Y. A. Gallant7, B. Giebels8, Stefan Gillessen1, J. F. Glicenstein11, P. Goret11, C. Hadjichristidis3, M. Hauser, G. Heinzelmann5, Gilles Henri10, G. Hermann1, Jim Hinton1, Werner Hofmann1, M. Holleran12, Dieter Horns1, O. C. de Jager12, Simon Johnston13, B. Khélifi1, J. G. Kirk1, Nu. Komin6, A. Konopelko6, A. Konopelko1, I. J. Latham3, R. Le Gallou3, Anne Lemiere, M. Lemoine-Goumard8, N. Leroy8, O. Martineau-Huynh4, Thomas Lohse6, A. Marcowith4, Conor Masterson4, Conor Masterson1, T. J. L. McComb3, M. de Naurois4, S. J. Nolan3, A. Noutsos3, K. J. Orford3, J. L. Osborne3, M. Ouchrif4, M. Panter1, Guy Pelletier10, S. Pita, Gerd Pühlhofer1, Michael Punch, B. C. Raubenheimer12, Martin Raue5, J. Raux4, S. M. Rayner3, I. Redondo4, I. Redondo8, A. Reimer14, Olaf Reimer14, J. Ripken5, L. Rob15, L. Rolland4, Gavin Rowell1, V. Sahakian2, L. Saugé10, S. Schlenker6, Reinhard Schlickeiser14, C. Schuster14, Ullrich Schwanke6, M. Siewert14, O. Skjæraasen16, Helene Sol4, R. Steenkamp17, C. Stegmann6, J.-P. Tavernet4, Regis Terrier, C. G. Théoret, M. Tluczykont8, M. Tluczykont4, G. Vasileiadis7, Christo Venter12, P. Vincent4, Heinrich J. Völk1, Stefan Wagner 
01 Oct 2005
TL;DR: The discovery of very-high-energy (VHE) γ-ray emission of the binary system PSR B1259−63/SS 2883 of a radio pulsar orbiting a massive, luminous Be star in a highly eccentric orbit provides unambiguous evidence for particle acceleration to multi-TeV energies in thebinary system.
Abstract: We report the discovery of very-high-energy (VHE) γ-ray emission of the binary system PSR B1259−63/SS 2883 of a radio pulsar orbiting a massive, luminous Be star in a highly eccentric orbit. The observations around the 2004 periastron passage of the pulsar were performed with the four 13 m Cherenkov telescopes of the HESS experiment, recently installed in Namibia and in full operation since December 2003. Between February and June 2004, a γ-ray signal from the binary system was detected with a total significance above 13σ. The flux was found to vary significantly on timescales of days which makes PSR B1259−63 the first variable galactic source of VHE γ-rays observed so far. Strong emission signals were observed in pre- and post-periastron phases with a flux minimum around periastron, followed by a gradual flux decrease in the months after. The measured time-averaged energy spectrum above a mean threshold energy of 380 GeV can be fitted by a simple power law F0(E/ 1T eV) −Γ with a photon index Γ= 2.7 ± 0.2stat ± 0.2sys and flux normalisation F0 = (1.3 ± 0.1stat ± 0.3sys) × 10 −12 TeV −1 cm −2 s −1 .T his detection of VHE γ-rays provides unambiguous evidence for particle acceleration to multi-TeV energies in the binary system. In combination with coeval observations of the X-ray synchrotron emission by the RXTE and INTEGRAL instruments, and assuming the VHE γ-ray emission to be produced by the inverse Compton mechanism, the magnetic field strength can be directly estimated to be of the order of 1 G.

Journal ArticleDOI
TL;DR: This paper compares the properties of various norms that are dual of Sobolev or Besov norms, and proposes a decomposition model which splits an image into three components: a first one containing the structure of the image, a second one the texture of theimage, and a third one the noise.
Abstract: Following a recent work by Y. Meyer, decomposition models into a geometrical component and a textured component have recently been proposed in image processing. In such approaches, negative Sobolev norms have seemed to be useful to modelize oscillating patterns. In this paper, we compare the properties of various norms that are dual of Sobolev or Besov norms. We then propose a decomposition model which splits an image into three components: a first one containing the structure of the image, a second one the texture of the image, and a third one the noise. Our decomposition model relies on the use of three different semi-norms: the total variation for the geometrical component, a negative Sobolev norm for the texture, and a negative Besov norm for the noise. We illustrate our study with numerical examples.

Journal ArticleDOI
TL;DR: This model shows that visual artifacts after demosaicing are due to aliasing between luminance and chrominance and could be solved using a preprocessing filter, and gives new insights for the representation of single-color per spatial location images.
Abstract: There is an analogy between single-chip color cameras and the human visual system in that these two systems acquire only one limited wavelength sensitivity band per spatial location. We have exploited this analogy, defining a model that characterizes a one-color per spatial position image as a coding into luminance and chrominance of the corresponding three colors per spatial position image. Luminance is defined with full spatial resolution while chrominance contains subsampled opponent colors. Moreover, luminance and chrominance follow a particular arrangement in the Fourier domain, allowing for demosaicing by spatial frequency filtering. This model shows that visual artifacts after demosaicing are due to aliasing between luminance and chrominance and could be solved using a preprocessing filter. This approach also gives new insights for the representation of single-color per spatial location images and enables formal and controllable procedures to design demosaicing algorithms that perform well compared to concurrent approaches, as demonstrated by experiments.

Journal ArticleDOI
Stefan Schael1, R. Barate2, R. Brunelière2, I. De Bonis2  +275 moreInstitutions (28)
TL;DR: The full LEP-1 data set collected with the ALEPH detector at the Z pole during 1991-1995 is analyzed in order to measure the tau decay branching fractions as discussed by the authors.

Journal ArticleDOI
TL;DR: In this paper, the authors investigated the damage tracks induced by tightly focused infrared femtosecond laser pulses in the bulk of a fused silica sample and observed two types of irreversible damage.
Abstract: We investigate experimentally and numerically the damage tracks induced by tightly focused $(\mathrm{NA}=0.5)$ infrared femtosecond laser pulses in the bulk of a fused silica sample. Two types of irreversible damage are observed. The first damage corresponds to a permanent change of refractive index without structural modifications (type I). It appears for input pulse energies beyond $0.1\phantom{\rule{0.3em}{0ex}}\ensuremath{\mu}\mathrm{J}$. It takes the form of a narrow track extending over more than $100\phantom{\rule{0.3em}{0ex}}\ensuremath{\mu}\mathrm{m}$ at higher input powers. It is attributed to a change of the polarizability of the medium, following a filamentary propagation which generates an electron-hole plasma through optical field ionization. A second type of damage occurs for input pulse energies beyond $0.3\phantom{\rule{0.3em}{0ex}}\ensuremath{\mu}\mathrm{J}$ (type II). It takes the form of a pear-shaped structural damage associated with an electron-ion plasma triggered by avalanche. The temporal evolution of plasma absorption is studied by pump-probe experiments. For type I damage, a fast electron-hole recombination is observed. Type II damage is linked with a longer absorption.

Journal ArticleDOI
Felix Aharonian1, A. G. Akhperjanian1, Klaus-Michael Aye2, A. R. Bazer-Bachi3, M. Beilicke1, Wystan Benbow1, David Berge1, P. Berghaus4, Konrad Bernlöhr1, Catherine Boisson5, O. Bolz1, C. Borgmeier6, Ilana M. Braun1, F. Breitling6, A. M. Brown2, J. Bussons Gordo7, P. M. Chadwick2, L.-M. Chounet8, R. Cornils1, Luigi Costamante1, B. Degrange8, A. Djannati-Ataï4, L. O'c. Drury9, Guillaume Dubus1, Tulun Ergin6, P. Espigat4, F. Feinstein1, P. Fleury8, G. Fontaine8, Stefan Funk1, Y. A. Gallant1, B. Giebels8, Stefan Gillessen1, P. Goret10, C. Hadjichristidis2, M. Hauser, G. Heinzelmann11, Gilles Henri12, German Hermann1, Jim Hinton1, Werner Hofmann1, M. Holleran13, Dieter Horns1, O. C. de Jager13, I. Jung1, B. Khélifi1, Nu. Komin6, A. Konopelko1, I. J. Latham2, R. Le Gallou2, A. Lemière4, M. Lemoine8, N. Leroy8, Thomas Lohse6, A. Marcowith3, Conor Masterson1, T. J. L. McComb2, M. de Naurois1, S. J. Nolan2, A. Noutsos2, K. J. Orford1, J. L. Osborne1, M. Ouchrif5, M. Panter1, Guy Pelletier12, S. Pita4, G. Pühlhofer1, Michael Punch4, B. C. Raubenheimer13, M. Raue1, J. Raux5, S. M. Rayner2, I. Redondo8, A. Reimer14, Olaf Reimer14, J. Ripken11, L. Rob15, L. Rolland5, Gavin Rowell1, V. Sahakian16, L. Saugé1, S. Schlenker6, Reinhard Schlickeiser14, C. Schuster14, U. Schwanke6, M. Siewert14, Helene Sol5, R. Steenkamp17, C. Stegmann6, J.-P. Tavernet5, R. Terrier4, C. G. Théoret4, M. Tluczykont8, D. J. van der Walt13, G. Vasileiadis1, Christo Venter13, P. Vincent5, B. Visser13, Heinrich J. Völk1, Stefan Wagner 
25 Mar 2005-Science
TL;DR: A first sensitive survey of the inner part of the Milky Way with the High Energy Stereoscopic System (HESS) reveals a population of eight previously unknown firmly detected sources of very high energy γ-rays.
Abstract: Very high energy gamma-rays probe the long-standing mystery of the origin of cosmic rays. Produced in the interactions of accelerated particles in astrophysical objects, they can be used to image cosmic particle accelerators. A first sensitive survey of the inner part of the Milky Way with the High Energy Stereoscopic System (HESS) reveals a population of eight previously unknown firmly detected sources of very high energy gamma-rays. At least two have no known radio or x-ray counterpart and may be representative of a new class of "dark" nucleonic cosmic ray sources.

Journal ArticleDOI
TL;DR: A methodology for optimal design of financial instruments aimed to hedge some forms of risk that is not traded on financial markets and is reduced to a unique inf-convolution problem involving a transformation of the initial risk measures.
Abstract: We develop a methodology for optimal design of financial instruments aimed to hedge some forms of risk that is not traded on financial markets. The idea is to minimize the risk of the issuer under the constraint imposed by a buyer who enters the transaction if and only if her risk level remains below a given threshold. Both agents have also the opportunity to invest all their residual wealth on financial markets, but with different access to financial investments. The problem is reduced to a unique inf-convolution problem involving a transformation of the initial risk measures.

Journal ArticleDOI
TL;DR: In this article, the effective N = 1, D = 4 supergravity for the seven main moduli of type IIA orientifolds with D6 branes, compactified on T 6 /(Z2 × Z2) in the presence of general fluxes, was derived.

Journal ArticleDOI
TL;DR: In this paper, the authors investigated the relationship between government support for R&D and expenditure financed privately by firms using a comprehensive plant level data set for the manufacturing sector in the Republic of Ireland.
Abstract: This paper investigates the relationship between government support for R&D and R&D expenditure financed privately by firms using a comprehensive plant level data set for the manufacturing sector in the Republic of Ireland. We find that for domestic plants small grants serve to increase private R&D spending, while too large a grant may crowd out private financing of R&D. In contrast, evidence for foreign establishments suggests that grant provision causes neither additionality nor crowding out effects of private R&D financing, regardless of the size of the subsidy.

Journal ArticleDOI
TL;DR: The dynamical systems approach to stochastic approximation is generalized to the case where the mean differential equation is replaced by a differential inclusion, and the limit set theorem is extended to this situation.
Abstract: The dynamical systems approach to stochastic approximation is generalized to the case where the mean differential equation is replaced by a differential inclusion. The limit set theorem of Benaim and Hirsch is extended to this situation. Internally chain transitive sets and attractors are studied in detail for set-valued dynamical systems. Applications to game theory are given, in particular to Blackwell's approachability theorem and the convergence of fictitious play.

Journal ArticleDOI
TL;DR: Solidification of a chitosan-glycerol phosphate/blood implant in microfracture defects improved cartilage repair compared with microfractionure alone by increasing the amount of tissue and improving its biochemical composition and cellular organization.
Abstract: Background: Microfracture is a surgical procedure that is used to treat focal articular cartilage defects. Although joint function improves following microfracture, the procedure elicits incomplete repair. As blood clot formation in the microfracture defect is an essential initiating event in microfracture therapy, we hypothesized that the repair would be improved if the microfracture defect were filled with a blood clot that was stabilized by the incorporation of a thrombogenic and adhesive polymer, specifically, chitosan. The objectives of the present study were to evaluate (1) blood clot adhesion in fresh microfracture defects and (2) the quality of the repair, at six months postoperatively, of microfracture defects that had been treated with or without chitosan-glycerol phosphate/blood clot implants, using a sheep model. Methods: In eighteen sheep, two 1-cm2 full-thickness chondral defects were created in the distal part of the femur and treated with microfracture; one defect was made in the medial femoral condyle, and the other defect was made in the trochlea. In four sheep, microfracture defects were created bilaterally; the microfracture defects in one knee received no further treatment, and the microfracture defects in the contralateral knee were filled with chitosan-glycerol phosphate/autologous whole blood and the implants were allowed to solidify. Fresh defects in these four sheep were collected at one hour postoperatively to compare the retention of the chitosan-glycerol phosphate/blood clot with that of the normal clot and to define the histologic characteristics of these fresh defects. In the other fourteen sheep, microfracture defects were made in only one knee and either were left untreated (control group; six sheep) or were treated with chitosan-glycerol phosphate/blood implant (treatment group; eight sheep), and the quality of repair was assessed histologically, histomorphometrically, and biochemically at six months postoperatively. Results: In the defects that were examined one hour postoperatively, chitosan-glycerol phosphate/blood clots showed increased adhesion to the walls of the defects as compared with the blood clots in the untreated microfracture defects. After histological processing, all blood clots in the control microfracture defects had been lost, whereas chitosanglycerol phosphate/blood clot adhered to and was partly retained on the surfaces of the defect. At six months, defects that had been treated with chitosan-glycerol phosphate/blood were filled with significantly more hyaline repair tissue (p < 0.05) compared with control defects. Repair tissue from medial femoral condyle defects that had been treated with chitosan-glycerol phosphate/blood contained more cells and more collagen compared with control defects and showed complete restoration of glycosaminoglycan levels. Conclusions: Solidification of a chitosan-glycerol phosphate/blood implant in microfracture defects improved cartilage repair compared with microfracture alone by increasing the amount of tissue and improving its biochemical composition and cellular organization. Clinical Relevance: The use of chitosan-glycerol phosphate/blood implants in conjunction with microfracture can improve the structural and compositional properties of repaired cartilage. These effects may result in better integration, improved biomechanical properties, and longer durability of the repair tissue.

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TL;DR: In this paper, the knowledge about machining of nonconducting materials using electrochemical discharge phenomenon is reviewed up to this date with some particular attention to the electrochemical point of view.
Abstract: Machining with electrochemical discharges is an unconventional technology able to machine several electrically non-conductive materials like glass or some ceramics. After almost 40 years of its first mention in literature, this technology remains an academic application and was never applied in industrial context. The knowledge about machining of non-conducting materials using electrochemical discharge phenomenon is reviewed up to this date with some particular attention to the electrochemical point of view. Some main limiting factors are highlighted and possible solutions are discussed.

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TL;DR: A correlation of features along the line T(1) = 4T(2) provides strong supportive evidence for the surface diffusion model of (1)H nuclear spin relaxation in cements and for a multimodal discrete pore size distribution.
Abstract: We report the first nuclear magnetic resonance NMR two-dimensional correlation T1-T2 and T2-T2 measurements of hydrating cement pastes. A small but distinct cross peak in the two-dimensional relaxation spectrum provides the first direct evidence of chemical exchange of water between gel and capillary pores occurring over the first 14 days of hydration. A correlation of features along the line T1=4T2 provides strong supportive evidence for the surface diffusion model of 1 H nuclear spin relaxation in cements and for a multimodal discrete pore size distribution. Differences in detail of the results are reported for white cement paste and white cement paste with added silica fume. Both the method and the theory presented can be applied more widely to other high surface area materials with other reactive surface areas.

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TL;DR: In this paper, a perturbative approach was proposed to define background redefinitions in string amplitudes in a systematic fashion, which has been shown to be useful in the context of supersymmetry breaking.

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TL;DR: A new method of measuring joint angle using a combination of accelerometers and gyroscopes is presented, which is able to provide joint angles in real-time, and ready for use in gait analysis.
Abstract: A new method of measuring joint angle using a combination of accelerometers and gyroscopes is presented. The method proposes a minimal sensor configuration with one sensor module mounted on each segment. The model is based on estimating the acceleration of the joint center of rotation by placing a pair of virtual sensors on the adjacent segments at the center of rotation. In the proposed technique, joint angles are found without the need for integration, so absolute angles can be obtained which are free from any source of drift. The model considers anatomical aspects and is personalized for each subject prior to each measurement. The method was validated by measuring knee flexion-extension angles of eight subjects, walking at three different speeds, and comparing the results with a reference motion measurement system. The results are very close to those of the reference system presenting very small errors (rms=1.3, mean=0.2, SD=1.1 deg) and excellent correlation coefficients (0.997). The algorithm is able to provide joint angles in real-time, and ready for use in gait analysis. Technically, the system is portable, easily mountable, and can be used for long term monitoring without hindrance to natural activities.