Institution
Hasanuddin University
Education•Makassar, Indonesia•
About: Hasanuddin University is a education organization based out in Makassar, Indonesia. It is known for research contribution in the topics: Population & Medicine. The organization has 5839 authors who have published 5267 publications receiving 25893 citations. The organization is also known as: Universitas Hasanuddin.
Topics: Population, Medicine, Coral reef, Agriculture, Government
Papers published on a yearly basis
Papers
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TL;DR: Using amplicon sequencing of the 16S ribosomal RNA gene, it is found that when seagrass meadows are present, there was a 50% reduction in the relative abundance of potential bacterial pathogens capable of causing disease in humans and marine organisms.
Abstract: Plants are important in urban environments for removing pathogens and improving water quality. Seagrass meadows are the most widespread coastal ecosystem on the planet. Although these plants are known to be associated with natural biocide production, they have not been evaluated for their ability to remove microbiological contamination. Using amplicon sequencing of the 16S ribosomal RNA gene, we found that when seagrass meadows are present, there was a 50% reduction in the relative abundance of potential bacterial pathogens capable of causing disease in humans and marine organisms. Moreover, field surveys of more than 8000 reef-building corals located adjacent to seagrass meadows showed twofold reductions in disease levels compared to corals at paired sites without adjacent seagrass meadows. These results highlight the importance of seagrass ecosystems to the health of humans and other organisms.
301 citations
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227 citations
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TL;DR: Reduced Herbivory resulted in faster algal growth and consequent overgrowth and mortality of coral tissue, demonstrating the critical importance of herbivory to the outcome of the competitive interaction.
174 citations
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National University of Singapore1, Naturalis2, Curtin University3, University of the Ryukyus4, The Chinese University of Hong Kong5, Ramkhamhaeng University6, Vietnam Academy of Science and Technology7, American University in Cairo8, Davao del Norte State College9, Universiti Malaysia Sabah10, Hasanuddin University11, Indonesian Institute of Sciences12
TL;DR: This review highlights several key characteristics of urban coral reefs, including "reef compression" (a decline in bathymetric range with increasing turbidity and decreasing water clarity over time and relative to shore), dominance by domed coral growth forms and low reef complexity, variable city-specific inshore-offshore gradients.
151 citations
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TL;DR: The elucidation of key regulators of energy balance and insulin signaling have revolutionized the understanding of fat and sugar metabolism and their intimate link, and the three ‘lipidsensing’ (PPARα, PPARγ and PPARδ) exemplify this connection, regulating diverse aspects of lipid and glucose homeostasis, and serving as bonafide therapeutic targets.
Abstract: BACKGROUND: Obesity is a growing threat to global health by virtue of its association with insulin resistance, inflammation, hypertension, and dyslipidemia, collectively known as the metabolic syndrome (MetS). The nuclear receptors PPARα and PPARγ are therapeutic targets for hypertriglyceridemia and insulin resistance, respectively, and drugs that modulate these receptors are currently in clinical use. More recent work on the PPARδ has uncovered a dual benefit for both hypertriglyceridemia and insulin resistance, highlighting the broad potential of PPARs in the treatment of metabolic disease. CONTENT: We have learned much about PPARs, the metabolic fat sensors, and the molecular pathways they regulate. Through their distinct tissue distribution and specific target gene activation, the three PPARs together control diverse aspects of fatty acid metabolism, energy balance, insulin sensitivity glucose homeostasis, inflammation, hypertension and atherosclerosis. These studies have advanced our understanding of the etiology for the MetS. Mechanisms revealed by these studies highlight the importance of emerging concepts, such as the endocrine function of adipose tissue, tissue-tissue cross-talk and lipotoxicity, in the pathogenesis of type 2 diabetes mellitus and CVD. SUMMARY: The elucidation of key regulators of energy balance and insulin signaling have revolutionized our understanding of fat and sugar metabolism and their intimate link. The three ‘lipidsensing’ (PPARα, PPARγ and PPARδ) exemplify this connection, regulating diverse aspects of lipid and glucose homeostasis, and serving as bonafide therapeutic targets. KEYWORDS: Peroxisome Proliferator, Activated Receptor, Metabolic Syndrome
149 citations
Authors
Showing all 5896 results
Name | H-index | Papers | Citations |
---|---|---|---|
Carl Abelardo T. Antonio | 60 | 106 | 66867 |
David V. Thiel | 32 | 331 | 4614 |
Jamaluddin Jompa | 31 | 145 | 4454 |
Din Syafruddin | 28 | 111 | 2935 |
Mochammad Hatta | 23 | 237 | 2308 |
Tomoyuki Shibata | 19 | 27 | 1264 |
Abdul Wahab | 17 | 95 | 835 |
David H. Muljono | 17 | 38 | 2449 |
Dahlang Tahir | 17 | 113 | 1201 |
Mawardi Bahri | 15 | 75 | 701 |
Firzan Nainu | 14 | 60 | 580 |
Firdaus Hamid | 14 | 41 | 850 |
Akbar Tahir | 14 | 56 | 1889 |
Muhammad Yusuf | 13 | 155 | 811 |
Muhammad Rizal | 13 | 77 | 689 |