Hasanuddin University

About: Hasanuddin University is a education organization based out in Makassar, Indonesia. It is known for research contribution in the topics: Population & Medicine. The organization has 5839 authors who have published 5267 publications receiving 25893 citations. The organization is also known as: Universitas Hasanuddin.

Petrology, geochemistry and tectonic significance of serpentinized ultramafic rocks from the South Arm of Sulawesi, Indonesia

Abstract: Serpentinized ultramafic rocks occur in two separate basement complexes in the South Arm of Sulawesi, the Bantimala and Barru Blocks. We present petrographic, mineral chemical and geochemical data for these rocks, and interpret them in terms of petrogenesis and tectonic setting. The rocks of both blocks show strong serpentinization of original anhydrous silicates. The Bantimala ultramafics consist mainly of peridotite (harzburgite and dunite) and clinopyroxenite, with lenses of podiform chromitite. Metamorphism is evidenced by the occurrence of amphibolite-facies tremolite schist. In contrast, the Barru ultramafics consist of harzburgite peridotite and podiform chromitite, which also show an amphibolite-facies overprint that in this case may be related to intrusion by a large dacite/granodiorite body. Whole-rock trace element analyses and spinel compositions show that the Barru harzburgite is depleted relative to primitive mantle, and has had some melt extracted. In contrast, the Bantimala dunite, harzburgite and clinopyroxenite are cumulates. Both are derived from a supra-subduction zone environment, and were obducted during the closure of small back-arc basins. If there has been no rotation of the blocks, then the Bantimala ultramafics were emplaced from an ENE direction, while the Barru ultramafics were emplaced from the WNW. The ultramafic suites from these two blocks are juxtaposed with metamorphic assemblages, which were later intruded by younger volcanics, particularly in the Barru Block.

Prognostic properties of hypoalbuminemia in COVID-19 patients: A systematic review and diagnostic meta-analysis

Abstract: BACKGROUND: Coronavirus disease 2019 (COVID-19) elicits robust inflammatory reaction that may result in a declining albumin serum level. This meta-analysis aimed to evaluate the prognostic properties of hypoalbuminemia for poor prognosis and factors that may influence the relationship. METHOD: A systematic literature search of PubMed was conducted from inception to April 22, 2021. The main exposure was albumin level below normal range-defined by the included studies. The outcome of interest was composite poor outcome that comprises of mortality, severity, and the requirement of mechanical ventilation or intensive care unit. RESULTS: There were 6200 patients from 19 studies. Meta-analysis showed that hypoalbuminemia was associated with composite poor outcome (OR 6.97 (95% CI 4.20-11.55), p < 0.001; I2 = 91.3%, p < 0.001). Meta-regression analysis showed that age (p = 0.44), gender (p = 0.76), HT (p = 0.97), DM (p = 0.40), CKD (p = 0.65), liver disease (p = 0.72), and malignancy (p = 0.84) did not affect the association. Subgroup analysis showed that hypoalbuminemia increased mortality (OR 6.26 (95% CI 3.26-12.04), p < 0.001; I2 = 69.6%, p < 0.01) and severity of the disease (OR 7.32 (95%CI 3.94-13.59), p < 0.001; I2 = 92.5%, p < 0.01). Pooled diagnostic analysis of hypoalbuminemia yielded a sensitivity of 0.63 (95% CI 0.52-0.72), specificity of 0.81 (95% CI 0.73-0.87), and AUC of 0.77. The probability of poor outcome was 70% in patients with hypoalbuminemia and 24% in patients with normal albumin level. CONCLUSION: Hypoalbuminemia was associated with poor prognosis in COVID-19 patients.

Xenia Negatively Affecting Kopyor Nut Yield in Kalianda Tall Kopyor and Pati Dwarf Kopyor Coconuts

Abstract: Xenia is a phenomenon usually associated with phenotype characters controlled by a single recessive gene. The genotype of pollen donor directly determines the phenotype of fruits or seeds harvested from female recipients. Kopyor coconut is a unique coconut mutant and its formation is an example of xenia, since the genotype of the pollen donor determines the phenotype of the harvested nuts. The objectives of this research were to evaluate xenia in two types of kopyor coconuts (i.e. Kalianda Kopyor Tall and Pati Kopyor Dwarf), determine effects of homozygous KK normal and heterozygous Kk Kopyor coconut ratio, and effects of homozygous KK normal coconuts removal from mix population on yield of Kopyor nuts. For Kalianda Tall Kopyor coconut, field observations were conducted at three kopyor coconut plantations in Kalianda district, Lampung Selatan, Lampung-Indonesia while observations of Pati Dwarf Kopyor were conducted at Tayu district, Pati, Central Java-Indonesia. In both regions, coconut provenances were mapped using GPS and sub-samples were taken based on determined criteria. For each sampled tree, observations were recorded for the following variables: nut yield and yield components. The quantitative data were subjected to t-test statistical analysis to evaluate the significant differences among the observed parameters. Results of this experiment showed the presence of more homozygous KK normal coconuts among provenances of Kalianda Tall heterozygous Kk Kopyor coconut resulted in lower harvested kopyor nuts than the expected value. Moreover, removal of homozygous KK normal coconuts from a mixed coconut population increased yield of kopyor nuts. Those results indicated xenia occurred in both Kalianda Tall and Pati Dwarf Kopyor coconuts and it negatively affected the kopyor nut yield.