Korea University

About: Korea University is a education organization based out in Seoul, South Korea. It is known for research contribution in the topics: Population & Catalysis. The organization has 39756 authors who have published 82424 publications receiving 1860927 citations. The organization is also known as: Bosung College & Bosung Professional College.

Amide I vibrational dynamics of N-methylacetamide in polar solvents: the role of electrostatic interactions.

Abstract: The vibrational frequency of the amide I transition of peptides is known to be sensitive to the strength of its hydrogen bonding interactions. In an effort to account for interactions with hydrogen bonding solvents in terms of electrostatics, we study the vibrational dynamics of the amide I coordinate of N-methylacetamide in prototypical polar solvents: D2O, CDCl3, and DMSO-d6. These three solvents have varying hydrogen bonding strengths, and provide three distinct solvent environments for the amide group. The frequency−frequency correlation function, the orientational correlation function, and the vibrational relaxation rate of the amide I vibration in each solvent are retrieved by using three-pulse vibrational photon echoes, two-dimensional infrared spectroscopy, and pump−probe spectroscopy. Direct comparisons are made to molecular dynamics simulations. We find good quantitative agreement between the experimentally retrieved and simulated correlation functions over all time scales when the solute−solve...

VUDDY: A Scalable Approach for Vulnerable Code Clone Discovery

Abstract: The ecosystem of open source software (OSS) has been growing considerably in size. In addition, code clones - code fragments that are copied and pasted within or between software systems - are also proliferating. Although code cloning may expedite the process of software development, it often critically affects the security of software because vulnerabilities and bugs can easily be propagated through code clones. These vulnerable code clones are increasing in conjunction with the growth of OSS, potentially contaminating many systems. Although researchers have attempted to detect code clones for decades, most of these attempts fail to scale to the size of the ever-growing OSS code base. The lack of scalability prevents software developers from readily managing code clones and associated vulnerabilities. Moreover, most existing clone detection techniques focus overly on merely detecting clones and this impairs their ability to accurately find "vulnerable" clones. In this paper, we propose VUDDY, an approach for the scalable detection of vulnerable code clones, which is capable of detecting security vulnerabilities in large software programs efficiently and accurately. Its extreme scalability is achieved by leveraging function-level granularity and a length-filtering technique that reduces the number of signature comparisons. This efficient design enables VUDDY to preprocess a billion lines of code in 14 hour and 17 minutes, after which it requires a few seconds to identify code clones. In addition, we designed a security-aware abstraction technique that renders VUDDY resilient to common modifications in cloned code, while preserving the vulnerable conditions even after the abstraction is applied. This extends the scope of VUDDY to identifying variants of known vulnerabilities, with high accuracy. In this study, we describe its principles and evaluate its efficacy and effectiveness by comparing it with existing mechanisms and presenting the vulnerabilities it detected. VUDDY outperformed four state-of-the-art code clone detection techniques in terms of both scalability and accuracy, and proved its effectiveness by detecting zero-day vulnerabilities in widely used software systems, such as Apache HTTPD and Ubuntu OS Distribution.