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Institution

Leicester Royal Infirmary

HealthcareLeicester, United Kingdom
About: Leicester Royal Infirmary is a healthcare organization based out in Leicester, United Kingdom. It is known for research contribution in the topics: Population & Carotid endarterectomy. The organization has 5300 authors who have published 6204 publications receiving 208464 citations.


Papers
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Journal ArticleDOI
TL;DR: Five concerns about the development of the speciality of palliative medicine in Britain are identified: the lack of clarity about its remit; a potential shift of focus away from terminal care; the inappropriate use of medical technology; the role of other health workers; the consequences for hospice care.
Abstract: The emergence of the speciality of palliative medicine in the UK has been generally welcomed and can be seen as a continuation of the attempts to improve the care of dying people begun by the modern hospice movement. However, not everyone has welcomed the new speciality unreservedly. In part, this reflects a more general ambivalence and concern about the role of medicine in terminal care. After a brief discussion of the 'medicalization' of death and an overview of the hospital care of dying people, the paper identifies five concerns about the development of the speciality of palliative medicine in Britain. These are: the lack of clarity about its remit; a potential shift of focus away from terminal care; the inappropriate use of medical technology; the role of other health workers; the consequences for hospice care.

65 citations

Journal ArticleDOI
TL;DR: In this paper, the authors investigated the cardiovascular prognostic value post-AMI of CT-proET-1 and compared it to N-terminal pro-B-type natriuretic peptide (NTproBNP), a marker of death and heart failure.

65 citations

Journal ArticleDOI
TL;DR: Plasma catecholamine concentrations, changes in cardiovascular variables and acid-base status were increased during conventional compared with endovascular AAA repair.

65 citations

Journal ArticleDOI
TL;DR: The clinic population is re‐examined to determine whether the documented rise in the use of complementary therapy in children with skin disease has been accompanied by a rise in dietary manipulation.
Abstract: Summary Background In 1989 we demonstrated that 71% of children referred to our paediatric dermatology clinic with atopic dermatitis (AD) had been subject to dietary manipulation by their parents in order to manage their disease. We have re-examined our clinic population to determine whether the documented rise in the use of complementary therapy in children with skin disease has been accompanied by a rise in dietary manipulation. Objectives To qualify and quantify the usage of dietary manipulation in children with AD in secondary care. Methods A face-to-face structured questionnaire study of 100 children with AD. Results The mean age of the children interviewed was 7·3 years (median 5·9, range 0·6–17·1) and ethnic origin was 59% white, 35% Indo-Asian, 3% Afro-Caribbean and 3% mixed race. Seventy-five per cent of patients (75 of 100) had tried some form of dietary exclusion; the most common foods omitted were dairy products in 48% (36 of 75), eggs in 27% (20 of 75) and cow's milk in 25% (19 of 75). Forty-one per cent of patients (41 of 100) had tried some form of dietary supplementation. The most common dietary supplement was evening primrose oil in 59% (24 of 41), of whom 13% (three of 24) felt this had helped their skin. Only 51% (38 of 75) had consulted a doctor or dietician before commencing any dietary change, but 39% (29 of 75) felt that their skin had improved as a result of this dietary manipulation. Conclusions In comparison with our previous study, the proportion of patients excluding foods from their diet had increased from 71% to 75%. The proportion of these dietary changes that are unsupervised has remained the same, as have the food types avoided. The proportion of patients who report that unsupervised dietary manipulation is beneficial has increased from 10% to 39%.

65 citations

Journal ArticleDOI
TL;DR: These issues are illustrated by the examples of nitrates, angiotensin-converting-enzyme inhibitors, and magnesium in acute myocardial infarction but have general relevance to the validity and generalisability of simple trials.

64 citations


Authors

Showing all 5314 results

NameH-indexPapersCitations
George Davey Smith2242540248373
Nilesh J. Samani149779113545
Peter M. Rothwell13477967382
John F. Thompson132142095894
James A. Russell124102487929
Paul Bebbington11958346341
John P. Neoptolemos11264852928
Richard C. Trembath10736841128
Andrew J. Wardlaw9231133721
Melanie J. Davies8981436939
Philip Quirke8937834071
Kenneth J. O'Byrne8762939193
David R. Jones8770740501
Keith R. Abrams8635530980
Martin J. S. Dyer8537324909
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Performance
Metrics
No. of papers from the Institution in previous years
YearPapers
20234
202219
2021168
2020120
2019110
2018121