Institution
Leicester Royal Infirmary
Healthcare•Leicester, United Kingdom•
About: Leicester Royal Infirmary is a healthcare organization based out in Leicester, United Kingdom. It is known for research contribution in the topics: Population & Carotid endarterectomy. The organization has 5300 authors who have published 6204 publications receiving 208464 citations.
Papers published on a yearly basis
Papers
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TL;DR: The rarity of rupture and sac expansion confirms the predominantly benign nature of isolated type II endoleak and indicates patient and physician preference remain key in the absence of statistical support for a uniform approach.
Abstract: PurposeTo report a systematic review and meta-regression of the association between the threshold for intervention in patients with isolated type II endoleak after endovascular aneurysm repair (EVA...
80 citations
TL;DR: Nutritional status is compromised in the months/years following oesophagectomy and may never return to baseline levels and the role of extended nutritional support in this population remains unclear.
80 citations
University of Cambridge1, Wellcome Trust Sanger Institute2, Istanbul Medipol University3, Sultan Qaboos University4, Boston Children's Hospital5, Uludağ University6, Dokuz Eylül University7, University College London8, Leicester Royal Infirmary9, University of Manchester10, King Saud University11, Central Manchester University Hospitals NHS Foundation Trust12, Diana Princess of Wales Hospital13, Cambridge University Hospitals NHS Foundation Trust14, Cardiff University15, St George’s University Hospitals NHS Foundation Trust16, Queen Mary University of London17
TL;DR: The etiology of CH with GIS remains elusive, with only 59% attributable to mutations in TSHR or known dyshormonogenesis-associated genes in a cohort enriched for familial cases.
Abstract: This study made use of data generated by the UK10K Project and we acknowledge the contribution of the UK10K Consortium. This work was supported by Wellcome Trust Grants 100585/Z/12/Z (to N.S.), and 095564/Z/11/Z (to V.K.C.) and the National Institute for Health Research Cambridge Biomedical Research Center (to V.K.C., N.S.). E.G.S and C.A.A. are supported by the Wellcome Trust (098051). Funding for the UK10K Project was provided by the Wellcome Trust under award WT091310.
80 citations
TL;DR: The inflammatory and renal parameters in comparative cohorts of patients undergoing surgical or endovascular repair of abdominal aortic aneurysms (AAAs) were quantified to quantify activation of the clotting cascade.
Abstract: Purpose:To quantify the inflammatory and renal parameters in comparative cohorts of patients undergoing surgical or endovascular repair of abdominal aortic aneurysms (AAAs).Methods:Forty-three patients (41 men; ages 58–81 years) underwent endovascular or conventional aneurysm surgery according to aortic morphology. All patients received a standard general anesthetic and had 12 serial blood and urine samples collected during the perioperative period. Samples underwent analysis for the cytokines interleukin (IL) 1β, tumor necrosis factor-alpha (TNF-α), and IL-6. White cell and platelet activation were estimated indirectly by measuring sL-selectin and 11-dehydrothromboxane B2, respectively. The urinary albumin: creatinine ratio (ACR) and N-acetyl-β-d-glucosaminidase (NAG) activity were estimated to assess renal injury. Fibrinogen and fibrinogen degradation products were calculated to assess activation of the clotting cascade.Results:Twenty-three patients underwent endovascular AAA repair and 20 had conventio...
80 citations
TL;DR: Amantadine is effective treatment for and prophylaxis against influenza A during epidemics and new developments include rapid laboratory diagnosis, live attenuated vaccines, and antiviral drugs.
Abstract: Influenza causes enormous morbidity, death, and economic loss. Annual vaccination is strongly recommended for groups at high risk. Amantadine is effective treatment for and prophylaxis against influenza A during epidemics. New developments include rapid laboratory diagnosis, live attenuated vaccines, and antiviral drugs.
80 citations
Authors
Showing all 5314 results
| Name | H-index | Papers | Citations |
|---|---|---|---|
| George Davey Smith | 224 | 2540 | 248373 |
| Nilesh J. Samani | 149 | 779 | 113545 |
| Peter M. Rothwell | 134 | 779 | 67382 |
| John F. Thompson | 132 | 1420 | 95894 |
| James A. Russell | 124 | 1024 | 87929 |
| Paul Bebbington | 119 | 583 | 46341 |
| John P. Neoptolemos | 112 | 648 | 52928 |
| Richard C. Trembath | 107 | 368 | 41128 |
| Andrew J. Wardlaw | 92 | 311 | 33721 |
| Melanie J. Davies | 89 | 814 | 36939 |
| Philip Quirke | 89 | 378 | 34071 |
| Kenneth J. O'Byrne | 87 | 629 | 39193 |
| David R. Jones | 87 | 707 | 40501 |
| Keith R. Abrams | 86 | 355 | 30980 |
| Martin J. S. Dyer | 85 | 373 | 24909 |