Sofia University

About: Sofia University is a education organization based out in Sofia, Bulgaria. It is known for research contribution in the topics: Large Hadron Collider & Laser. The organization has 8533 authors who have published 15730 publications receiving 306320 citations. The organization is also known as: University of Sofia & BFUS.

SARS-CoV-2 vaccines and autoimmune diseases amidst the COVID-19 crisis.

Abstract: Coronavirus disease 2019 (COVID-19) pandemic has become challenging even for the most durable healthcare systems. It seems that vaccination, one of the most effective public-health interventions, presents a ray of hope to end the pandemic by achieving herd immunity. In this review, we aimed to cover aspects of the current knowledge of severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) vaccines and vaccine candidates in the light of autoimmune inflammatory diseases (AIIDs) and to analyze their potential in terms of safety and effectiveness in patients with AIIDs. Therefore, a focused narrative review was carried out to predict the possible implications of different types of SARS-CoV-2 vaccines which confer distinct immune mechanisms to establish immune response and protection against COVID-19: whole virus (inactivated or weakened), viral vector (replicating and non-replicating), nucleic acid (RNA, DNA), and protein-based (protein subunit, virus-like particle). Still, there is uncertainty among patients with AIIDs and clinicians about the effectiveness and safety of the new vaccines. There are a variety of approaches towards building a protective immunity against SARS-CoV-2. Only high-quality clinical trials would clarify the underlying immunological mechanisms of the newly implemented vaccines/adjuvants in patients living with AIIDs.

Study of exclusive two-photon production of W+W- in pp collisions at √s=7 TeV and constraints on anomalous quartic gauge couplings

Abstract: A search for exclusive or quasi-exclusive W(+)W(-) production by photon-photon interactions, pp to p(*)W(+)W(-)p(*), at sqrt(s) = 7 TeV is reported using data collected by the CMS detector with an integrated luminosity of 5.05 inverse femtobarns. Events are selected by requiring a mu(+/-)e(-/+) vertex with no additional associated charged tracks and dilepton transverse momentum pt(mu(+/-)e(-/+)) > 30 GeV. Two events passing all selection requirements are observed in the data, compared to a standard model expectation of 2.2 +/- 0.4 signal events with 0.84 +/- 0.15 background. The tail of the dilepton pt distribution is studied for deviations from the standard model. No events are observed with pt > 100 GeV. Model-independent upper limits are computed and compared to predictions involving anomalous quartic gauge couplings. The limits on the parameters a[W,(0,C)]/Lambda^2 with a dipole form factor and an energy cutoff Lambda(cutoff) = 500 GeV are of the order of 10E-4.

Measurements of Higgs boson properties in the diphoton decay channel in proton-proton collisions at √s=13 TeV

Abstract: Measurements of Higgs boson properties in the H → γγ decay channel are reported. The analysis is based on data collected by the CMS experiment in proton-proton collisions at $ \sqrt{s}=13 $ TeV during the 2016 LHC running period, corresponding to an integrated luminosity of 35.9 fb$^{−1}$. Allowing the Higgs mass to float, the measurement yields a signal strength relative to the standard model prediction of 1.18$_{− 0.14}^{+ 0.17}$ = 1.18$_{− 0.11}^{+ 0.12}$ (stat)$_{− 0.07}^{+ 0.09}$ (syst)$_{− 0.06}^{+ 0.07}$ (theo), which is largely insensitive to the exact Higgs mass around 125 GeV. Signal strengths associated with the different Higgs boson production mechanisms, couplings to bosons and fermions, and effective couplings to photons and gluons are also measured.