Institution
Swedish Institute
Government•Stockholm, Sweden•
About: Swedish Institute is a government organization based out in Stockholm, Sweden. It is known for research contribution in the topics: Population & Health care. The organization has 1657 authors who have published 2301 publications receiving 103682 citations. The organization is also known as: Svenska Institutet.
Topics: Population, Health care, Cost effectiveness, Virus, Vaccination
Papers published on a yearly basis
Papers
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TL;DR: The environmental impact, fossil energy input and land use from using gasified biomass (cereal straw and short rotation willow) as feedstock in ammonium nitrate production were studied in a cradle-to-gate evaluation using life cycle assessment methodology.
88 citations
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TL;DR: WD was reproduced in ser onegative lactating cows and the cows showed a more severe general diseases than seronegative calves infected concurrently, suggesting that the same strains of BCV cause natural outbreaks of calf diarrhoea and WD.
87 citations
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TL;DR: Investigating dimensions of caregiving activities among elderly (75+) caregivers based on Nolan's model and studying the dimensions in relation to health-related quality of life predicted low MCS12, with a focus on early involvement on the part of the caregivers.
Abstract: The aim was to investigate dimensions of caregiving activities among elderly (75+) caregivers based on Nolan's model and to study the dimensions in relation to health-related quality of life (Short Form 12). Responses to a Swedish postal survey (n = 4278, response rate 75-79 years old: 60%; 80-84: 56%; 85-89: 48% and 90+: 42%) showed that 783 persons (18%) were helping another person due to that person's impaired health, 41.6% women, mean age for women 81.8 years (SD 4.96) and for men 81.7 years (SD 4.32). The postal questionnaire included SF-12, demographic data and questions about caregiving activities derived from Nolan's model, social network and contacts with health care. Adapting their activities to be prepared if something happened (52%), having regular contact to prevent problems (35%), helping in contacts with the hospital (57%), helping with instrumental activities of daily living (49%), personal activities of daily living (14%), medical care (11%) and helping to improve functions (14%) were the activities reported. Adapting own activities, regular contact, weak economy and needing instrumental help with daily living oneself predicted low MCS12. The importance of early involvement on the part of the caregivers was emphasized. (Less)
87 citations
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TL;DR: The results showed that S. mansoni coinfected mice had significantly higher levels of BCG bacilli in their organs and sustained greater lung pathology compared to Schistosoma uninfected controls, an indication that chronic worm infection could affect resistance/susceptibility to mycobacterial infections by impairing myCobacteria antigen specific Th1 type responses.
Abstract: The incidence of mycobacterial diseases is high and the efficacy of Bacillus Calmette Guerin (BCG) is low in most areas of the world where chronic worm infections are common. However, if and how concurrent worm infections could affect immunity to mycobacterial infections has not been elucidated. In this study we investigated whether infection of mice with Schistosoma mansoni could affect the ability of the animals to control Mycobacterium bovis BCG infection and the immune response to mycobacterial antigens. BALB/c mice subclinically infected with S. mansoni were challenged with M. bovis BCG via the intravenous route. The ability of the animals to contain the replication of M. bovis BCG in their organs, lung pathology as well as the in vitro mycobacterial and worm antigen induced immune responses were evaluated. The results showed that S. mansoni coinfected mice had significantly higher levels of BCG bacilli in their organs and sustained greater lung pathology compared to Schistosoma uninfected controls. Moreover, Schistosoma infected mice show depressed mycobacterial antigen specific Th1 type responses. This is an indication that chronic worm infection could affect resistance/susceptibility to mycobacterial infections by impairing mycobacteria antigen specific Th1 type responses. This finding is potentially important in the control of TB in helminth endemic parts of the world.
87 citations
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TL;DR: Promogran with GWC may be cost-effective, perhaps even cost-saving, under a wide variety of assumptions for the treatment of neuropathic foot ulcers.
Abstract: Objective: This study aimed to estimate the cost-effectiveness of treating non-superficial diabetic foot ulcers with Promogran plus good wound care (GWC) compared with GWC alone in four European countries (France, Germany, Switzerland and UK). Methods: An existing Markov-based health economic model of non-superficial diabetic foot ulcers was adapted to incorporate the relative efficacy of Promogran compared with GWC alone as demonstrated in a randomised controlled trial. Treatment with Promogran was modelled for a maximum of three months. Country-specific treatment costs were used to estimate the incremental cost per ulcer-free day gained over 12 months. Some parameter assumptions were changed to assess the sensitivity of the results. Results: Within the first three months of treatment, 26% of ulcers in the Promogran cohort healed compared with 20.7% in the GWC cohort. Over the 12 months, the average number of months spent in the healed state was 3.41 (GWC) and 3.75 (Promogran). Promogran treatment was fo...
87 citations
Authors
Showing all 1667 results
Name | H-index | Papers | Citations |
---|---|---|---|
Kevin Marsh | 128 | 567 | 55356 |
Gerhard Andersson | 118 | 902 | 49159 |
Staffan Normark | 96 | 289 | 29787 |
Tirone E. David | 82 | 382 | 22078 |
Olof Nyrén | 78 | 274 | 23034 |
Antonella d'Arminio Monforte | 74 | 462 | 26093 |
Björn Lindman | 74 | 526 | 21454 |
Job J. Bwayo | 74 | 190 | 16928 |
Jan Albert | 73 | 323 | 19740 |
Dan I. Andersson | 73 | 257 | 20958 |
Jan Vinjé | 72 | 233 | 19778 |
Helena Johansson | 72 | 320 | 27007 |
David Bergqvist | 71 | 597 | 22200 |
Lars Engstrand | 69 | 302 | 20090 |
Joan Ivanov | 67 | 211 | 13473 |