Institution
Swedish Institute
Government•Stockholm, Sweden•
About: Swedish Institute is a government organization based out in Stockholm, Sweden. It is known for research contribution in the topics: Population & Health care. The organization has 1657 authors who have published 2301 publications receiving 103682 citations. The organization is also known as: Svenska Institutet.
Topics: Population, Health care, Cost effectiveness, Virus, Vaccination
Papers published on a yearly basis
Papers
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TL;DR: In this article, a solid-solution model allowing compositional variations in one dimension is developed from the zeroth approximation of nearest-neighbor interactions, which predicts the existence of periodically modulated structures in order as well as in precipitation systems.
437 citations
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Utrecht University1, University of Foggia2, University of Bergen3, University of Milan4, Pierre-and-Marie-Curie University5, The Catholic University of America6, Katholieke Universiteit Leuven7, Sheba Medical Center8, Robert Koch Institute9, Athens State University10, Centre Hospitalier de Luxembourg11, University of Erlangen-Nuremberg12, Los Alamos National Laboratory13, Swedish Institute14, Carlos III Health Institute15, French Institute of Health and Medical Research16, Geneva College17, University of Vienna18, University of Belgrade19, University of Siena20
TL;DR: In this paper, the authors determined the baseline rate of drug resistance in 2208 therapy-naive patients recently and chronically infected with HIV-1 from 19 European countries during 1996-2002.
Abstract: BackgroundInfection with drug-resistant human immunodeficiency virus type 1 (HIV-1) can impair the response to combination therapy. Widespread transmission of drug-resistant variants has the disturbing potential of limiting future therapy options and affecting the efficacy of postexposure prophylaxispenta increase-spacing 1>MethodsWe determined the baseline rate of drug resistance in 2208 therapy-naive patients recently and chronically infected with HIV-1 from 19 European countries during 1996–2002ResultsIn Europe, 1 of 10 antiretroviral-naive patients carried viruses with ⩾1 drug-resistance mutation. Recently infected patients harbored resistant variants more often than did chronically infected patients (13.5% vs. 8.7%; P=.006). Non-B viruses (30%) less frequently carried resistance mutations than did subtype B viruses (4.8% vs. 12.9%; P<.01). Baseline resistance increased over time in newly diagnosed cases of non-B infection: from 2.0% (1/49) in 1996–1998 to 8.2% (16/194) in 2000–2001ConclusionsDrug-resistant variants are frequently present in both recently and chronically infected therapy-naive patients. Drug-resistant variants are most commonly seen in patients infected with subtype B virus, probably because of longer exposure of these viruses to drugs. However, an increase in baseline resistance in non-B viruses is observed. These data argue for testing all drug-naive patients and are of relevance when guidelines for management of postexposure prophylaxis and first-line therapy are updated
433 citations
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TL;DR: The high rate of hospital admission, prolonged stay in hospital, and long period of inactivity all continue to constitute a social and health care burden of community-acquired pneumonia in the general population.
Abstract: In this prospective study, the authors assessed the incidence, aetiology, and outcome of patients with community-acquired pneumonia in the general population. From December 1993 to November 1995, a study was performed in a mixed residential-industrial urban population of the "Maresme" region in Barcelona, Spain. All subjects > or =14 yrs of age (annual average population size 74,368 inhabitants) with clinically suspected community-acquired pneumonia were registered. All cases were re-evaluated by chest radiographs on the 5th day of illness and at monthly intervals until complete recovery. Urine and blood samples were obtained for culture and antigen detection. When lower respiratory tract secretions were obtained, these were also cultured. There were 241 patients with community-acquired pneumonia, with an annual incidence rate of 1.62 cases (95% confidence interval, 1.42-1.82) per 1,000 inhabitants. Incidence rates increased by age groups and were higher in males than in females. Of 232 patients with aetiological data, 104 had an identifiable aetiology. A total of 114 pathogens were found (single pathogen 94, two pathogens 10). There were 81 episodes of bacterial infection and 33 of viral infection. The most common pathogens were Streptococcus pneumoniae, Chlamydia pneumoniae, and influenza A and B viruses. No case of Hantavirus infection was found. The rate of hospital admission was 61.4% with a mean+/-SD length of 11.7+/-10.1 days, a mean period of 23.0+/-14.3 days inactivity, and an overall mortality rate of 5%. The high rate of hospital admission, prolonged stay in hospital, and long period of inactivity all continue to constitute a social and health care burden of community-acquired pneumonia.
431 citations
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TL;DR: Different waste treatment options for municipal solid waste have been studied in a systems analysis as mentioned in this paper, and different combinations of incineration, materials recycling of separated plastic and cardboard have been compared.
418 citations
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TL;DR: In this paper, the effects of pH on the gel network structure have been characterized by means of different microscopy techniques, and the results of the microstructure correlated with previously published data on fracture properties.
401 citations
Authors
Showing all 1667 results
Name | H-index | Papers | Citations |
---|---|---|---|
Kevin Marsh | 128 | 567 | 55356 |
Gerhard Andersson | 118 | 902 | 49159 |
Staffan Normark | 96 | 289 | 29787 |
Tirone E. David | 82 | 382 | 22078 |
Olof Nyrén | 78 | 274 | 23034 |
Antonella d'Arminio Monforte | 74 | 462 | 26093 |
Björn Lindman | 74 | 526 | 21454 |
Job J. Bwayo | 74 | 190 | 16928 |
Jan Albert | 73 | 323 | 19740 |
Dan I. Andersson | 73 | 257 | 20958 |
Jan Vinjé | 72 | 233 | 19778 |
Helena Johansson | 72 | 320 | 27007 |
David Bergqvist | 71 | 597 | 22200 |
Lars Engstrand | 69 | 302 | 20090 |
Joan Ivanov | 67 | 211 | 13473 |