University of Bologna

About: University of Bologna is a education organization based out in Bologna, Emilia-Romagna, Italy. It is known for research contribution in the topics: Population & Galaxy. The organization has 38387 authors who have published 115176 publications receiving 3460869 citations. The organization is also known as: Università di Bologna & UNIBO.

Towards an electricity-powered world

Abstract: The purpose of this review is examination of the present scenario of electricity production and investigation of whether an electricity powered world is possible, indicating which primary energy forms should be preferably utilized. Currently, most of the primary energy used by mankind, including that employed to generate electricity, comes from fossil fuels, which need to be phased out because they bring about severe damage to climate, environment, and human health and, additionally, their stock will be largely depleted during the present century. All the energy technologies poised to replace those based on fossil fuels, namely nuclear and renewables (wind, hydro, concentrated solar power, photovoltaics, biomass, geothermal, tidal, wave) essentially produce electricity, and this suggests that we will progressively shift to an electricity-based economy over the course of the 21st century. The economic, technical, ethical and social issues entangled with nuclear technologies and the unexpectedly fast expansion of renewable energies (particularly wind and solar) point to an increasingly important role of the latter in electricity generation. The present one way utility-to-customer energy system, designed over one century ago, will need substantial reshaping to enable the build up of a smart grid capable of dealing with variable renewable supply and fluctuating end-user demand by exchange of information between customer and utility. To accomplish this result, effort in research and development of storage devices and facilities on the small (e.g., batteries, capacitors) and large (e.g., pumped hydro, compressed air storage, electrolytic hydrogen) scale is needed. In the medium and long term, the expansion of electricity production will also likely lead to progressive replacement of internal combustion engines with electric motors in the automotive sector, accompanied by a shift from individual to mass transportation systems. We have still a long way out of the fossil fuel era, but this challenge can be won only if carbon-free electricity largely replaces the direct combustion of irreplaceable and climate-altering fossil fuel resources.

Fertility and obstetric outcome after laparoscopic myomectomy of large myomata: a randomized comparison with abdominal myomectomy

Abstract: The purpose of this study was to compare, in infertile patients, the efficacy of laparoscopic myomectomy versus abdominal myomectomy, in restoring fertility and to evaluate the obstetric outcomes. Between January 1993 and January 1998, 131 patients of reproductive age, with anamnesis of infertility, underwent myomectomy because of the presence of at least one large myoma (diameter greater than or = 5 cm). Patients were randomly selected for treatment by laparotomy (n = 65) or laparoscopy (n = 66). The two groups were homogeneous for number, size and position of large myomata. Significant differences were found in the post-operative outcome: febrile morbidity (> 38 degrees C) was more frequent in the abdominal than in the laparoscopic group (26.2 versus 12.1%; P < 0.05). Laparotomy caused a more pronounced haemoglobin drop (2.17 +/- 1.57 versus 1.33 +/- 1.23; P < 0.001); three patients received a blood transfusion after laparotomy and none after laparoscopy. The post-operative hospital stay was shorter in the laparoscopic group (142.80 +/- 34.60 versus 75.61 +/- 37.09 h; P < 0.001). No significant differences were found between the two groups as concerns pregnancy rate (55.9% after laparotomy, 53.6% after laparoscopy), abortion rate (12.1 versus 20%), preterm delivery (7.4 versus 5%) and the use of Caesarean section (77.8 versus 65%). No case of uterine rupture during pregnancy or labour was observed.

Approaches to semi-synthetic minimal cells: a review

Abstract: Following is a synthetic review on the minimal living cell, defined as an artificial or a semi-artificial cell having the minimal and sufficient number of components to be considered alive. We describe concepts and experiments based on these constructions, and we point out that an operational definition of minimal cell does not define a single species, but rather a broad family of interrelated cell-like structures. The relevance of these researches, considering that the minimal cell should also correspond to the early simple cell in the origin of life and early evolution, is also explained. In addition, we present detailed data in relation to minimal genome, with observations cited by several authors who agree on setting the theoretical full-fledged minimal genome to a figure between 200 and 300 genes. However, further theoretical assumptions may significantly reduce this number (i.e. by eliminating ribosomal proteins and by limiting DNA and RNA polymerases to only a few, less specific molecular species). Generally, the experimental approach to minimal cells consists in utilizing liposomes as cell models and in filling them with genes/enzymes corresponding to minimal cellular functions. To date, a few research groups have successfully induced the expression of single proteins, such as the green fluorescence protein, inside liposomes. Here, different approaches are described and compared. Present constructs are still rather far from the minimal cell, and experimental as well as theoretical difficulties opposing further reduction of complexity are discussed. While most of these minimal cell constructions may represent relatively poor imitations of a modern full-fledged cell, further studies will begin precisely from these constructs. In conclusion, we give a brief outline of the next possible steps on the road map to the minimal cell.

Microbes and Alzheimer's disease

Abstract: We are researchers and clinicians working on Alzheimer’s disease (AD) or related topics, and we write to express our concern that one particular aspect of the disease has been neglected, even thoug ...