Book ChapterDOI
A structure for deoxyribose nucleic acid
James D. Watson,Francis Crick +1 more
TLDR
In this article, the authors summarize Watson and Crick's descrip2on of the DNA molecule and conclude that the purpose of this ar2cle was to find out why they wrote it.Abstract:
What is the purpose of this ar2cle? (Why did Watson and Crick write this ar2cle?) _________________________ _________________________ _________________________ _________________________ _________________________ _________________________ _________________________ Summarize Watson and Crick’s descrip2on of the DNA molecule. ________________________________________________________ ________________________________________________________ ________________________________________________________ ________________________________________________________ ________________________________________________________ ________________________________________________________ ________________________________________________________ ________________________________________________________ ________________________________________________________ ________________________________________________________ ___________________________________________________read more
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Journal ArticleDOI
A vision for the future of genomics research
TL;DR: The Human Genome Project (HGP) as mentioned in this paper was the first attempt to obtain a high-quality, comprehensive sequence of the human genome, in this fiftieth anniversary year of the discovery of the double-helical structure of DNA.
Journal ArticleDOI
DNA damage and repair
TL;DR: The aesthetic appeal of the DNA double helix initially hindered notions of DNA mutation and repair, which would necessarily interfere with its pristine state, but it has since been recognized that DNA is subject to continuous damage and the cell has an arsenal of ways of responding to such injury.
Journal ArticleDOI
The structure of dna
James D. Watson,Francis Crick +1 more
TL;DR: The detailed structure described by Crick and Watson has been shown to have too large a diameter, and a drawing has been given of an improved model which is in fairly good agreement with the s-ray data.
Journal ArticleDOI
Mapping and analysis of quantitative trait loci in experimental populations
TL;DR: The lessons learnt from this evolution of QTL methodology might also be generally relevant to other types of functional genomics approach that are aimed at the dissection of complex phenotypes, such as microarray assessment of gene expression.
Journal ArticleDOI
Mechanisms of human DNA repair: an update.
TL;DR: This review is aimed at updating the current knowledge of the various repair pathways by providing an overview of DNA-repair genes and the corresponding proteins, participating either directly in DNA repair, or in checkpoint control and signaling of DNA damage.
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The sequence of the human genome.
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