Journal ArticleDOI
Breast Cancer Screening and Optimizing Recommendations.
TLDR
Differences in screening recommendations for average risk and high-risk women as well as the frequently suggested modalities for screening these populations are discussed.About:
This article is published in Seminars in Roentgenology.The article was published on 2018-08-31. It has received 3 citations till now. The article focuses on the topics: Breast cancer screening & Overdiagnosis.read more
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Breast cancer: An insight into its inflammatory, molecular, pathological and targeted facets with update on investigational drugs.
TL;DR: This review highlights various approaches, including the importance of clinical, pathological, and molecular aspects of BC, as well as targeting approaches for tumors through nanocarriers and their clinical trials for management of BC.
Journal ArticleDOI
Exciting Potential of Nanoparticlized Lipidic System for Effective Treatment of Breast Cancer and Clinical Updates: A Translational Prospective
TL;DR: This review highlights on the importance of chemotherapeutics based lipidic nanocarriers and their anticipated use for the treatment of BC.
Journal ArticleDOI
A review of the latest research medications and information on the inflammatory, molecular, pathological, and targeted aspects of breast cancer
TL;DR: In this article , the clinical, pathological, and molecular aspects of breast cancer are all highlighted in this overview, and the involvement of risk factors, biomarkers, immunotherapy, and experimental medications through tumor targets and immune systems in the treatment of BC has been discussed.
References
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Journal ArticleDOI
Cancer statistics, 2018
TL;DR: The combined cancer death rate dropped continuously from 1991 to 2015 by a total of 26%, translating to approximately 2,378,600 fewer cancer deaths than would have been expected if death rates had remained at their peak.
Journal ArticleDOI
Average risks of breast and ovarian cancer associated with BRCA1 or BRCA2 mutations detected in case series unselected for family history: a combined analysis of 22 studies
Antonis C. Antoniou,Paul D.P. Pharoah,Steven A. Narod,Harvey A. Risch,Jorunn E. Eyfjord,John L. Hopper,Niklas Loman,Håkan Olsson,Oskar T. Johannsson,Åke Borg,Barbara Pasini,Paolo Radice,Siranoush Manoukian,Diana Eccles,Nelson L.S. Tang,E. Olah,Hoda Anton-Culver,Ellen Warner,Jan Lubinski,Jacek Gronwald,Bohdan Górski,Hrafn Tulinius,Steinunn Thorlacius,Hannaleena Eerola,Heli Nevanlinna,Kirsi Syrjäkoski,Olli Kallioniemi,Deborah J. Thompson,Christopher H. Evans,Julian Peto,Julian Peto,Fiona Lalloo,D G R Evans,Douglas F. Easton +33 more
TL;DR: Risks in carriers were higher when based on index breast cancer cases diagnosed at <35 years of age and for variation in risk by mutation position for both genes, and some evidence for a reduction in risk in women from earlier birth cohorts is found.
Journal ArticleDOI
Projecting Individualized Probabilities of Developing Breast Cancer for White Females Who Are Being Examined Annually
Mitchell H. Gail,Louise A. Brinton,David P. Byar,Donald K. Corle,Sylvan B. Green,Catherine Schairer,John J. Mulvihill +6 more
TL;DR: To assist in medical counseling, a method to estimate the chance that a woman with given age and risk factors will develop breast cancer over a specified interval is presented and individualized breast cancer probabilities are calculated.
Journal ArticleDOI
Genetic Heterogeneity and Penetrance Analysis of the BRCA1 and BRCA2 Genes in Breast Cancer Families
D Ford,Douglas F. Easton,Michael R. Stratton,Steven A. Narod,David E. Goldgar,Peter Devilee,D. T. Bishop,Barbara L. Weber,Gilbert M. Lenoir,Jenny Chang-Claude,Hagay Sobol,M D Teare,Jeffery P. Struewing,Adalgeir Arason,Siegfried Scherneck,Julian Peto,Timothy R. Rebbeck,Patricia N. Tonin,Susan L. Neuhausen,Rosa B. Barkardottir,Jorunn E. Eyfjord,Henry T. Lynch,Bruce A.J. Ponder,Simon A. Gayther,J.M. Birch,Annika Lindblom,Dominique Stoppa-Lyonnet,Y. J. Bignon,Åke Borg,U Hamann,Neva E. Haites,Rodney J. Scott,Christine Maugard,Hans F. A. Vasen,Susanne Seitz,Lisa A. Cannon-Albright,Andrew Craig Schofield,Moraima Zelada-Hedman +37 more
TL;DR: The lifetime risk of breast cancer appears similar to the risk in BRCA1 carriers, but there was some suggestion of a lower risk in bRCA2 carriers <50 years of age.
Journal ArticleDOI
Effect of radiotherapy after breast-conserving surgery on 10-year recurrence and 15-year breast cancer death: meta-analysis of individual patient data for 10,801 women in 17 randomised trials
Sarah C. Darby,Paul McGale,C Correa,Carolyn W. Taylor,R Arriagada,Mike Clarke,D Cutter,C Davies,Marianne Ewertz,Jon Godwin,Richard Gray,Lori J. Pierce,Timothy J. Whelan,Yaochen Wang,Richard Peto +14 more
TL;DR: In this paper, the authors conducted a meta-analysis of individual patient data for 10,801 women in 17 randomised trials of radiotherapy versus no radiotherapy after breast-conserving surgery, 8337 of whom had pathologically confirmed node-negative (pN0) or node-positive (nN+) disease.