Journal ArticleDOI
Enzymatic production and biological activities of chitosan oligosaccharides (COS): A review
Se-Kwon Kim,Niranjan Rajapakse +1 more
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TLDR
This review has summarized different enzymatic preparation methods of COS and some of their reported biological activities, such as antimicrobial, anticancer, antioxidant, and immunostimulant effects are depend on their physico-chemical properties.About:
This article is published in Carbohydrate Polymers.The article was published on 2005-12-14. It has received 763 citations till now.read more
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Chitooligosaccharides Modulate Glucose-Lipid Metabolism by Suppressing SMYD3 Pathways and Regulating Gut Microflora
Qiu-Tong Wang,Jiang Yajie,Xue-Gang Luo,Chang Wang,Nan Wang,Hongpeng He,Tong-Cun Zhang,Chen Liehuan +7 more
TL;DR: This study is the first to illustrate that COS mediate glucose and lipid metabolism disorders by regulating gut microbiota and SMYD3-mediated signaling pathways by inhibiting HMGCR and exerting hypolipidemic functions.
Journal ArticleDOI
The Antibacterial Activity of Chitosan Products Blended with Monoterpenes and Their Biofilms against Plant Pathogenic Bacteria
TL;DR: The biological bioactivities of chitosan products with a viscosity-average molecular weight ranging from 22 to 846 kDa in combination with the most active monoterpenes, out of 10 tested, against four plant pathogenic bacteria, may provide novel insights into the functions of ch itosan and some monoterspenes and potentially allow their use for food protection from microbial attack.
Journal ArticleDOI
Recombinant expression of chitosanase from Bacillus subtilis HD145 in Pichia pastoris.
TL;DR: A chitosanase-producing bacterium, Bacillus subtilis HD145 CCTCC AB 2010353, was isolated from a soil sample and enzymatic productions of chitooligosaccharides from Chitosans of various deacetylation degrees mainly ranged from chitobiose to chitopentamer.
Journal ArticleDOI
Statistical optimization of chitosanase production by Aspergillus sp. QD-2 in submerged fermentation
Hui Zhang,Qing Sang,Wenhui Zhang +2 more
TL;DR: In this article, the path of steepest ascent was undertaken to determine the optimal region of three significant factors, i.e., NH4 2SO4, inoculum size and initial pH, for chitosanase production.
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Biomacromolecular affinity: interactions between lysozyme and regioselectively sulfated chitosan.
TL;DR: The results indicate that 6-O-sulfate groups may be responsible for the high affinity and specific interaction of sulfated chitosan with lysozyme, while 2-O'sulfate and 3-o-solfate groups are unfavorable to this interaction.
References
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Journal ArticleDOI
Food applications of chitin and chitosans
TL;DR: Application of chitinous products in foods and pharmaceuticals as well as processing aids has received considerable attention in recent years as exotic synthetic compounds are losing their appeal.
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Antibacterial action of chitosan
TL;DR: Fungal chitosan had significantly less antibiotic effect than CH and CL, and was shown to be concentration dependent with 0.1 mg/mL more effective than 2.0 and 5.0 mg/ mL.
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Chitosan: A Unique Polysaccharide for Drug Delivery
TL;DR: The aim of this review is to give an insight into the many potential applications of chitosan as a pharmaceutical drug carrier.
BookDOI
Chitin in nature and technology
TL;DR: Chitin has been a landmark for polysaccharides and modified chitins, besides chitin itself, to the point that three International Conferences on Chitin / Chitosan were convened (Boston, U.S. A. 1977, Sapporo, Japan 1982 and Senigallia, Italy 1985).
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Antimicrobial effect of chitooligosaccharides produced by bioreactor
TL;DR: In this paper, the antibacterial effect of three kinds of chitooligosaccharides with relatively higher molecular weights (HMWCOS), medium molecular weight (MMWCOS), and lower molecular weight, respectively, was evaluated against various microorganisms.