Open AccessJournal Article
Estimates of deaths associated with seasonal influenza - United States, 1976-2007.
Mark G. Thompson,David K. Shay,H. Zhou,Carolyn B. Bridges,Po Yung Cheng,Erin Burns,Joseph S. Bresee,Nancy J. Cox +7 more
TLDR
The findings indicated the wide variation in the estimated number of deaths from season to season was closely related to the particular influenza virus types and subtypes in circulation.Abstract:
Influenza infections are associated with thousands of deaths every year in the United States, with the majority of deaths from seasonal influenza occurring among adults aged >or=65 years. For several decades, CDC has made annual estimates of influenza-associated deaths, which have been used in influenza research and to develop influenza control and prevention policy. To update previously published estimates of the numbers and rates of influenza-associated deaths during 1976-2003 by adding four influenza seasons through 2006-07, CDC used statistical models with data from death certificate reports. National mortality data for two categories of underlying cause of death codes, pneumonia and influenza causes and respiratory and circulatory causes, were used in regression models to estimate lower and upper bounds for the number of influenza-associated deaths. Estimates by seasonal influenza virus type and subtype were examined to determine any association between virus type and subtype and the number of deaths in a season. This report summarizes the results of these analyses, which found that, during 1976-2007, estimates of annual influenza-associated deaths from respiratory and circulatory causes (including pneumonia and influenza causes) ranged from 3,349 in 1986-87 to 48,614 in 2003-04. The annual rate of influenza-associated death in the United States overall during this period ranged from 1.4 to 16.7 deaths per 100,000 persons. The findings also indicated the wide variation in the estimated number of deaths from season to season was closely related to the particular influenza virus types and subtypes in circulation.read more
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Estimates of global seasonal influenza-associated respiratory mortality: a modelling study
A. Danielle Iuliano,Katherine Roguski,Howard H. Chang,David Muscatello,Rakhee Palekar,Stefano Tempia,Cheryl Cohen,Jon Michael Gran,Jon Michael Gran,Dena L. Schanzer,Benjamin J. Cowling,Peng Wu,Jan Kynčl,Li Wei Ang,Minah Park,Monika Redlberger-Fritz,Hongjie Yu,Laura Espenhain,Anand Krishnan,Gideon O. Emukule,Liselotte van Asten,Susana Silva,Suchunya Aungkulanon,Udo Buchholz,Marc-Alain Widdowson,Joseph S. Bresee,Eduardo Azziz-Baumgartner,Po-Yung Cheng,Fatimah S. Dawood,Ivo M. Foppa,Sonja J. Olsen,Michael Haber,Caprichia Jeffers,C. Raina MacIntyre,Anthony T. Newall,James G. Wood,Michael Kundi,Therese Popow-Kraupp,Makhdum Ahmed,Mahmudur Rahman,Fatima Marinho,C Viviana Sotomayor Proschle,Natalia Vergara Mallegas,Feng Luzhao,Li Sa,Juliana Barbosa-Ramírez,Diana Malo Sanchez,Leandra Abarca Gomez,Xiomara Badilla Vargas,aBetsy Acosta Herrera,María Josefa Llanés,Thea Kølsen Fischer,Tyra Grove Krause,Kåre Mølbak,Jens Nielsen,Ramona Trebbien,Alfredo Bruno,Jenny Ojeda,Hector Ramos,Matthias an der Heiden,Leticia del Carmen Castillo Signor,Carlos Enrique Serrano,Rohit Bhardwaj,Mandeep S. Chadha,Venkatesh Vinayak Narayan,Soewarta Kosen,Michal Bromberg,Aharona Glatman-Freedman,Zalman Kaufman,Yuzo Arima,Kazunori Oishi,Sandra S. Chaves,Bryan O. Nyawanda,Reem Abdullah Al-Jarallah,Pablo A Kuri-Morales,Cuitláhuac Ruiz Matus,Maria Eugenia Jimenez Corona,Alexander Burmaa,Oyungerel Darmaa,Majdouline Obtel,Imad Cherkaoui,Cees C van den Wijngaard,Wim van der Hoek,Michael G Baker,Don Bandaranayake,Ange Bissielo,Sue Huang,Liza Lopez,Claire Newbern,Elmira Flem,Gry M Grøneng,Siri Hauge,Federico G de Cosío,Yadira De Molto,Lourdes Moreno Castillo,María Agueda Cabello,Marta Von Horoch,José L. Medina Osis,Ausenda Machado,Baltazar Nunes,Ana Paula Rodrigues,Emanuel Rodrigues,Cristian Calomfirescu,Emilia Lupulescu,Rodica Popescu,Odette Popovici,Dragan Bogdanovic,Marina Kostic,Konstansa Lazarevic,Zoran Milosevic,Branislav Tiodorovic,Mark I-Cheng Chen,Jeffery Cutter,Vernon J. Lee,Raymond T. P. Lin,Stefan Ma,Adam L. Cohen,Florette K. Treurnicht,Woo Joo Kim,Concha Delgado-Sanz,Salvador de mateo Ontañón,Amparo Larrauri,Inmaculada León,Fernando Vallejo,Rita Born,Christoph Junker,Daniel Koch,Jen-Hsiang Chuang,Wan-Ting Huang,Hung-Wei Kuo,Yi-Chen Tsai,Kanitta Bundhamcharoen,Malinee Chittaganpitch,Helen K. Green,Richard Pebody,Natalia Goñi,Hector Chiparelli,Lynnette Brammer,Desiree Mustaquim +138 more
TL;DR: These global influenza-associated respiratory mortality estimates are higher than previously reported, suggesting that previous estimates might have underestimated disease burden.
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Efficacy and effectiveness of influenza vaccines: a systematic review and meta-analysis
TL;DR: Influenza vaccines can provide moderate protection against virologically confirmed influenza, but such protection is greatly reduced or absent in some seasons.
Journal ArticleDOI
Prevention and Control of Seasonal Influenza with Vaccines: Recommendations of the Advisory Committee on Immunization Practices - United States, 2020-21 Influenza Season.
Lisa A. Grohskopf,Leslie Z. Sokolow,Leslie Z. Sokolow,Sonja J. Olsen,Joseph S. Bresee,Karen R. Broder,Ruth A. Karron +6 more
TL;DR: This report updates the 2017–18 recommendations of the Advisory Committee on Immunization Practices regarding the use of seasonal influenza vaccines in the United States and focuses on the recommendations for use of vaccines for the prevention and control of influenza during the 2018–19 season.
Journal ArticleDOI
Estimated global mortality associated with the first 12 months of 2009 pandemic influenza A H1N1 virus circulation: a modelling study
Fatimah S. Dawood,A. Danielle Iuliano,Carrie Reed,Martin I. Meltzer,David K. Shay,Po Yung Cheng,Don Bandaranayake,Robert F. Breiman,W. Abdullah Brooks,W. Abdullah Brooks,Philippe Buchy,Daniel R. Feikin,Karen B. Fowler,Aubree Gordon,Aubree Gordon,Nguyen Tran Hien,Peter Horby,Q. Sue Huang,Mark A. Katz,Anand Krishnan,Renu B. Lal,Joel M. Montgomery,Kåre Mølbak,Richard Pebody,Anne M. Presanis,Hugo Razuri,Anneke Steens,Yeny Tinoco,Jacco Wallinga,Hongjie Yu,Sirenda Vong,Joseph S. Bresee,Marc-Alain Widdowson +32 more
TL;DR: The global number of deaths during the first 12 months of virus circulation in each country and the estimate of respiratory and cardiovascular mortality associated with the 2009 pandemic influenza A H1N1 was 15 times higher than reported laboratory-confirmed deaths.
Journal ArticleDOI
Hospital Outbreak of Middle East Respiratory Syndrome Coronavirus
Abdullah M. Assiri,Allison McGeer,Trish M. Perl,Connie S. Price,Abdullah A. Al Rabeeah,Derek A. T. Cummings,Zaki N. Alabdullatif,Maher Assad,Abdulmohsen Almulhim,Hatem Q. Makhdoom,Hossam Madani,Rafat F. Alhakeem,Jaffar A. Al-Tawfiq,Matthew Cotten,Simon J. Watson,Paul Kellam,Paul Kellam,Alimuddin Zumla,Alimuddin Zumla,Ziad A. Memish +19 more
TL;DR: Person-to-person transmission of MERS-CoV can occur in health care settings and may be associated with considerable morbidity and surveillance and infection-control measures are critical to a global public health response.
References
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Journal ArticleDOI
Mortality Associated With Influenza and Respiratory Syncytial Virus in the United States
William W. Thompson,David K. Shay,Eric Weintraub,Lynnette Brammer,Nancy Cox,Larry J. Anderson,Keiji Fukuda +6 more
TL;DR: Mortality associated with both influenza and RSV circulation disproportionately affects elderly persons, and influenza deaths have increased substantially in the last 2 decades, in part because of aging of the population, highlighting the need for better prevention measures, including more effective vaccines and vaccination programs for elderly persons.
Journal ArticleDOI
Impact of Influenza Vaccination on Seasonal Mortality in the US Elderly Population
Lone Simonsen,Thomas A. Reichert,Cécile Viboud,William C. Blackwelder,Robert J. Taylor,Mark A. Miller +5 more
TL;DR: The decline in influenza-related mortality among people aged 65 to 74 years in the decade after the 1968 pandemic is attributed to the acquisition of immunity to the emerging A(H3N2) virus, and observational studies substantially overestimate vaccination benefit.
Journal ArticleDOI
Estimates of US influenza-associated deaths made using four different methods
William W. Thompson,Eric Weintraub,Praveen Dhankhar,Po-Yung Cheng,Lynnette Brammer,Martin I. Meltzer,Joseph S. Bresee,David K. Shay +7 more
TL;DR: A wide range of methods have been used for estimating influenza‐associated deaths in temperate countries, and direct comparisons of estimates produced by using different models with US mortality data have not been published.
Journal ArticleDOI
Estimating Influenza-Associated Deaths in the United States
William W. Thompson,Matthew R. Moore,Eric Weintraub,Po-Yung Cheng,Xiaoping Jin,Carolyn B. Bridges,Joseph S. Bresee,David K. Shay +7 more
TL;DR: It is suggested that discrepancies between the recent estimate and previous estimates of the number of influenza-associated deaths are attributable primarily to the use of different outcomes and methods, and that secondary bacterial infections will likely result in substantial morbidity and mortality during a future influenza pandemic, despite medical progress.
Journal ArticleDOI
Influenza: diagnosis, management, and prophylaxis.
TL;DR: Amantadine is effective treatment for and prophylaxis against influenza A during epidemics and new developments include rapid laboratory diagnosis, live attenuated vaccines, and antiviral drugs.