Journal ArticleDOI
Fish genomics and its impact on fundamental and applied research of vertebrate biology
Reads0
Chats0
TLDR
A recent overview of genomics data, address different approaches applicable to comparative genomics analyses, and illustrate these comparisons to better understand the complex mechanisms under the vertebrate genomes as mentioned in this paper, and summarize the applications in chromosomes research and cytogenomics.Abstract:
The living fishes span a unique and interesting set of animals because of their vast diversity, morphology, ecology, genetics and genomics, and higher importance to biology, economy and culture. During the past decade, the remarkable increase in fish genome sequencing has revolutionized comparative and evolutionary genomics, with the outcome of stimulating insights into vertebrate genome biology. Fish genomics has been transformed rapidly, with the availability of high-quality chromosome level genome assemblies and large collections of sequencing datasets, which are roadmaps for striking discoveries. Landmark achievements are being made; such as the accomplishment of fully assembled lungfish genome which is biggest genome ever sequenced. Here, we highlight current developments in vertebrate’s comparative genomics and discuss how fish genomes could be considered as vital resources for genomic studies. We present a recent overview of genomics data, address different approaches applicable to comparative genomics analyses, and illustrate these comparisons to better understand the complex mechanisms under the vertebrate genomes. We also summarize the applications in chromosomes research and cytogenomics.read more
Citations
More filters
Journal ArticleDOI
Fish as Model Systems to Study Epigenetic Drivers in Human Self-Domestication and Neurodevelopmental Cognitive Disorders
TL;DR: It is argued that fish provide model systems to study epigenetic drivers in human self-domestication and will pave the way for future studies using fish as models to investigate epigenetic changes as drivers of human-self domestication and as triggers of cognitive disorders.
Journal ArticleDOI
Integration of Maps Enables a Cytogenomics Analysis of the Complete Karyotype in Solea senegalensis
D. Ramírez,María Esther Rodríguez,Ismael Cross,Alberto Arias-Pérez,Manuel A. Merlo,Marco Anaya,Silvia Portela-Bens,Paulino Martínez,Francisca Robles,Carmelo Ruiz-Rejón,Laureana Rebordinos +10 more
TL;DR: Differences in the distribution and abundance of repetitive elements in chromosomes that have undergone remodeling processes during the course of evolution also suggest a possible role for simple repeat sequences in rearranged regions.
Posted ContentDOI
Fish as model systems to study epigenetic drivers in human self-domestication and neurodevelopmental cognitive disorders
TL;DR: In this paper , the authors compare genes that carry epigenetic changes in early domesticates of European sea bass with anatomically modern humans and neurodevelopmental cognitive disorders with abnormal self-domestication traits, i.e., schizophrenia, Williams syndrome and autism spectrum disorders.
Journal ArticleDOI
Salmonidae Genome: Features, Evolutionary and Phylogenetic Characteristics
Artem P. Dysin,Yuriy S. Shcherbakov,Olga Alexandrovna Nikolaeva,V. P. Terletskii,V. I. Tyshchenko,Natalia V. Dementieva +5 more
TL;DR: A comprehensive overview of the current state of research on the genomics and phylogeny of the various most studied subfamilies, genera, and individual salmonid species can be found in this article .
Journal ArticleDOI
Genome size estimation and its associations with body length, chromosome number and evolution in teleost fishes.
Basdeo Kushwaha,Naresh Sahebrao Nagpure,Shreya Srivastava,Manmohan Pandey,Ravindra Kumar,Sudhir Raizada,Suyash Agarwal,Mahender Singh,Valaparamail S Basheer,Rahul G. Kumar,Paramananda Das,Sofia P. Das,Siddhi Patnaik,Amrita Bit,Satish Kumar Srivastava,Achchhe Lal Vishwakarma,Chaitanya G. Joshi,Dinesh Kumar,Joykrushna Jena +18 more
TL;DR: In this paper , the authors examined the relationship between the genome size, chromosome number and body length across all fishes and found that body length was associated with genome size whereas no relationship was noticed between the GS and the chromosome number.
References
More filters
Journal ArticleDOI
Estimate of human gene number provided by genome-wide analysis using Tetraodon nigroviridis DNA sequence
H. Roest Crollius,Olivier Jaillon,Alain Bernot,Corinne Dasilva,Laurence Bouneau,Cécile Fischer,Cécile Fizames,Patrick Wincker,Philippe Brottier,F Quétier,William Saurin,Jean Weissenbach +11 more
TL;DR: Application of ‘Exofish’, a procedure based on homology searches, to identify human genes quickly and reliably, showed that the human genome contains 28,000–34,000 genes, and that Unigene contains less than 40% of the protein-coding fraction of thehuman genome.
Journal ArticleDOI
Whole-genome sequences of Malawi cichlids reveal multiple radiations interconnected by gene flow
Milan Malinsky,Hannes Svardal,Alexandra M. Tyers,Alexandra M. Tyers,Eric A. Miska,Eric A. Miska,Martin J. Genner,George F. Turner,Richard Durbin +8 more
TL;DR: In this paper, the authors characterized the genomic diversity of cichlid fish in Lake Malawi by sequencing 134 individuals covering 73 species across all major lineages and found that the average sequence divergence between species pairs is only 0.1-0.25%.
Journal ArticleDOI
Fish as model systems
TL;DR: Research techniques that enable scientists to make isogenic lines in a single generation, create and maintain mutants, culture cells, and transfer cloned genes into embryos signal an increasing role for fish as experimental models.
Journal ArticleDOI
Transcriptome analysis of psoriasis in a large case-control sample: RNA-seq provides insights into disease mechanisms.
Bingshan Li,Bingshan Li,Lam C. Tsoi,William R. Swindell,Johann E. Gudjonsson,Trilokraj Tejasvi,Andrew Johnston,Jun Ding,Jun Ding,Philip E. Stuart,Xianying Xing,James J. Kochkodan,John J. Voorhees,Hyun Min Kang,Rajan P. Nair,Gonçalo R. Abecasis,James T. Elder +16 more
TL;DR: In this article, the authors used high-throughput complementary DNA sequencing (RNA-seq) to assay the transcriptomes of lesional psoriatic and normal skin, which revealed multiple modules of coordinately expressed epidermal differentiation genes, overlapping significantly with genes regulated by the long noncoding RNA TINCR.
Journal ArticleDOI
Zebrafish as a model for infectious disease and immune function.
Con Sullivan,Carol H. Kim +1 more
TL;DR: The capabilities and potential of the zebrafish model system will be discussed, the results of these studies should provide important clues for the development of effective vaccines and prophylactic measures against bacterial and viral pathogens in economically important fishes.