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Fish genomics and its impact on fundamental and applied research of vertebrate biology

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TLDR
A recent overview of genomics data, address different approaches applicable to comparative genomics analyses, and illustrate these comparisons to better understand the complex mechanisms under the vertebrate genomes as mentioned in this paper, and summarize the applications in chromosomes research and cytogenomics.
Abstract
The living fishes span a unique and interesting set of animals because of their vast diversity, morphology, ecology, genetics and genomics, and higher importance to biology, economy and culture. During the past decade, the remarkable increase in fish genome sequencing has revolutionized comparative and evolutionary genomics, with the outcome of stimulating insights into vertebrate genome biology. Fish genomics has been transformed rapidly, with the availability of high-quality chromosome level genome assemblies and large collections of sequencing datasets, which are roadmaps for striking discoveries. Landmark achievements are being made; such as the accomplishment of fully assembled lungfish genome which is biggest genome ever sequenced. Here, we highlight current developments in vertebrate’s comparative genomics and discuss how fish genomes could be considered as vital resources for genomic studies. We present a recent overview of genomics data, address different approaches applicable to comparative genomics analyses, and illustrate these comparisons to better understand the complex mechanisms under the vertebrate genomes. We also summarize the applications in chromosomes research and cytogenomics.

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Journal ArticleDOI

Fish as Model Systems to Study Epigenetic Drivers in Human Self-Domestication and Neurodevelopmental Cognitive Disorders

TL;DR: It is argued that fish provide model systems to study epigenetic drivers in human self-domestication and will pave the way for future studies using fish as models to investigate epigenetic changes as drivers of human-self domestication and as triggers of cognitive disorders.
Journal ArticleDOI

Integration of Maps Enables a Cytogenomics Analysis of the Complete Karyotype in Solea senegalensis

TL;DR: Differences in the distribution and abundance of repetitive elements in chromosomes that have undergone remodeling processes during the course of evolution also suggest a possible role for simple repeat sequences in rearranged regions.
Posted ContentDOI

Fish as model systems to study epigenetic drivers in human self-domestication and neurodevelopmental cognitive disorders

TL;DR: In this paper , the authors compare genes that carry epigenetic changes in early domesticates of European sea bass with anatomically modern humans and neurodevelopmental cognitive disorders with abnormal self-domestication traits, i.e., schizophrenia, Williams syndrome and autism spectrum disorders.
Journal ArticleDOI

Salmonidae Genome: Features, Evolutionary and Phylogenetic Characteristics

TL;DR: A comprehensive overview of the current state of research on the genomics and phylogeny of the various most studied subfamilies, genera, and individual salmonid species can be found in this article .
Journal ArticleDOI

Genome size estimation and its associations with body length, chromosome number and evolution in teleost fishes.

TL;DR: In this paper , the authors examined the relationship between the genome size, chromosome number and body length across all fishes and found that body length was associated with genome size whereas no relationship was noticed between the GS and the chromosome number.
References
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Journal ArticleDOI

RNA-Seq technology and its application in fish transcriptomics.

TL;DR: An overview of each step of RNA-seq from library construction to the bioinformatic analysis of the data is provided and the recent biological insights obtained from the RNA- sequencing studies in a variety of fish species are discussed.
Journal ArticleDOI

Harnessing genomics to fast-track genetic improvement in aquaculture.

TL;DR: The authors review how genomics is being applied to aquaculture species at all stages of the domestication process to optimize selective breeding and how combining genomic selection with biotechnological innovations, such as genome editing and surrogate broodstock technologies, may further expedite genetic improvement in Aquaculture.
Journal ArticleDOI

Zebrafish as a cancer model.

TL;DR: The zebrafish model has created its own niche in cancer research, complementing existing models with its specific experimental advantages and characteristics, and screening possibilities not only for chemical modifiers but also for genetic enhancers and suppressors.