Journal ArticleDOI
Geminiviruses: masters at redirecting and reprogramming plant processes
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TLDR
This Review describes the current knowledge of how geminiviruses interact with their plant hosts and the functional consequences of these interactions.Abstract:
The family Geminiviridae is one of the largest and most important families of plant viruses. The small, single-stranded DNA genomes of geminiviruses encode 5-7 proteins that redirect host machineries and processes to establish a productive infection. These interactions reprogramme plant cell cycle and transcriptional controls, inhibit cell death pathways, interfere with cell signalling and protein turnover, and suppress defence pathways. This Review describes our current knowledge of how geminiviruses interact with their plant hosts and the functional consequences of these interactions.read more
Citations
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Journal ArticleDOI
ICTV Virus Taxonomy Profile: Geminiviridae.
F. Murilo Zerbini,Rob W. Briddon,Ali M. Idris,Darren P. Martin,Enrique Moriones,Jesús Navas-Castillo,Rafael F. Rivera-Bustamante,Philippe Roumagnac,Arvind Varsani +8 more
TL;DR: The geminiviruses are a family of small, non-enveloped viruses with single-stranded, circular DNA genomes of 2500–5200 bases causing economically important diseases in most tropical and subtropical regions of the world.
Journal ArticleDOI
Origins and evolution of viruses of eukaryotes: The ultimate modularity
TL;DR: Strikingly, evolution of all classes of eukaryotic viruses appears to have involved fusion between structural and replicative gene modules derived from different sources along with additional acquisitions of diverse genes.
Journal ArticleDOI
The Enhancement of Plant Disease Resistance Using CRISPR/Cas9 Technology.
Virginia Maria Grazia Borrelli,Vittoria Brambilla,Peter M. Rogowsky,Adriano Marocco,Alessandra Lanubile +4 more
TL;DR: Recently, CRISPR/Cas9 has largely overtaken the other genome editing technologies due to the fact that it is easier to design and implement, has a higher success rate, and is more versatile and less expensive.
Journal ArticleDOI
CRISPR/Cas9-mediated viral interference in plants
TL;DR: In this paper, the CRISPR/Cas9 system was used in plants to confer molecular immunity against DNA viruses, including the tomato yellow leaf curl virus (TYLCV).
Journal ArticleDOI
Conferring resistance to geminiviruses with the CRISPR-Cas prokaryotic immune system.
Nicholas J. Baltes,Aaron W. Hummel,Eva Konečná,Radim Cegan,Aaron N. Bruns,David M. Bisaro,Daniel F. Voytas +6 more
TL;DR: Transgenic plants expressing CRISPR–Cas reagents and challenged with BeYDV had reduced virus load and symptoms, thereby demonstrating a novel strategy for engineering resistance to geminiviruses.
References
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Journal ArticleDOI
Suppressors of RNA silencing encoded by the components of the cotton leaf curl begomovirus-betasatellite complex.
Imran Amin,Khadim Hussain,Rashid Akbergenov,Jitender S. Yadav,Javaria Qazi,Shahid Mansoor,Thomas Hohn,Claude M. Fauquet,Rob W. Briddon +8 more
TL;DR: This is the first time all proteins encoded by a geminiviruses (or begomovirus-betasatellite complex) have been examined and also the first for which four separate suppressors have been identified.
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Maize streak virus: an old and complex 'emerging' pathogen.
Dionne N. Shepherd,Darren P. Martin,Eric van der Walt,Kyle C. Dent,Kyle C. Dent,Arvind Varsani,Arvind Varsani,Edward P. Rybicki +7 more
TL;DR: Maize streak virus occurs throughout Africa, where it causes what is probably the most serious viral crop disease on the continent, and natural resistance to MSV in maize, and/or maize infections caused by non-maize-adapted MSV strains, can result in narrow, interrupted streaks and no obvious yield losses.
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Proliferating cell nuclear antigen transcription is repressed through an E2F consensus element and activated by geminivirus infection in mature leaves
TL;DR: Results demonstrate that geminivirus infection induces the accumulation of a host replication factor by activating transcription of its gene in mature tissues, most likely by overcoming E2F-mediated repression.
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Interaction between a geminivirus replication protein and the plant sumoylation system
TL;DR: Effects on geminivirus replication were observed in transgenic plants with altered levels of SUMO, the substrate for UBC9, and the host cell sumoylation enzyme, NbSCE1 (N. benthamiana SUMO-conjugating enzyme, homolog to Saccharomyces cerevisiae U BC9), was found to interact specifically with RepAC1.
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SUMO, a heavyweight player in plant abiotic stress responses
TL;DR: This review focuses on the emerging importance ofsumoylation in the abiotic stress response, summarizing the molecular implications of sumoylation and emphasizing how high-throughput approaches aimed at identifying the full set of SUMO targets will greatly enhance the understanding of the SUMO–abiotic stress association.