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Guide for the Care and Use of Laboratory Animals
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The article was published on 1996-02-01 and is currently open access. It has received 13908 citations till now. The article focuses on the topics: Animal Care Committees & Laboratory Animal Science.read more
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Ethical standards in sport and exercise science research: 2014 update·.
D. J. Harriss,Greg Atkinson +1 more
TL;DR: For publication in the International Journal of Sports Medicine (IJSM), studies involving human participants or animals must have been conducted in accordance with recognised ethical standards and national/international laws.
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Development and characterization of an in vivo central venous catheter Candida albicans biofilm model.
TL;DR: The rat central venous catheter model provides a model for further investigation into the molecular mechanisms of C. albicans biofilm biology and drug resistance and provides a means to study novel drug therapies and device technologies targeted to the control of biofilm-associated infections.
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Varenicline, an α4β2 nicotinic acetylcholine receptor partial agonist, selectively decreases ethanol consumption and seeking
TL;DR: The selectivity of varenicline in decreasing ethanol consumption combined with its reported safety profile and mild side effects in humans suggest that varenICline may prove to be a treatment for alcohol dependence.
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Retro-orbital injections in mice.
TL;DR: The authors report that they have routinely used retro-orbital injection of the venous sinus in the adult mouse to administer volumes up to 150 μl without incident and this technique is a useful alternative to tail vein injection for the administration of non-tumorigenic compounds.
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Ethical principles and standards for the conduct of human and animal biological rhythm research.
TL;DR: The basic expectations for the methods of human and animal biological rhythm research are outlined, both from the perspective of the fundamental criteria necessary for quality chronobiology investigation and from the perspectives of humane and ethical research on human beings and animals.
References
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Oxidants, antioxidants, and the degenerative diseases of aging
TL;DR: It is argued that this damage to DNA, protein, and lipid is a major contributor to aging and to degenerative diseases of aging such as cancer, cardiovascular disease, immune-system decline, brain dysfunction, and cataracts.
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Guide for the Care and Use of Laboratory Animals
TL;DR: The Guide for the Care and Use of Laboratory Animals by the Institute for Laboratory Animal Research (ILAR) of the National Research Council in the USA, is well known among most individuals involved in laboratory animal care and use and the overall intention is to support the readers to build a programme which creates a system of selfregulation and regulatory oversight.