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Guide for the Care and Use of Laboratory Animals
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The article was published on 1996-02-01 and is currently open access. It has received 13908 citations till now. The article focuses on the topics: Animal Care Committees & Laboratory Animal Science.read more
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Maternal high-fat intake predisposes nonalcoholic fatty liver disease in C57BL/6 offspring
Bianca Martins Gregório,Vanessa Souza-Mello,Jorge José de Carvalho,Carlos Alberto Mandarim-de-Lacerda,Marcia Barbosa Aguila +4 more
TL;DR: Programming by HF chow predisposes hepatic adverse remodeling in the liver of adult offspring, and insulin resistance and lower glucose transporter-2 expression were shown.
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Accumulation-Associated Protein Enhances Staphylococcus epidermidis Biofilm Formation under Dynamic Conditions and Is Required for Infection in a Rat Catheter Model
Carolyn R. Schaeffer,Keith M. Woods,G. Matt Longo,Megan R. Kiedrowski,Alexandra E. Paharik,Henning Büttner,Martin Christner,Robert Boissy,Alexander R. Horswill,Holger Rohde,Paul D. Fey +10 more
TL;DR: Results demonstrate Aap contributes to S. epidermidis infection, which may in part be due to A domain-mediated attachment to abiotic surfaces.
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Antibacterial activities of a fosfomycin/tobramycin combination: a novel inhaled antibiotic for bronchiectasis
David Macleod,Lynn M. Barker,Jennifer L. Sutherland,Suzanne C. Moss,Jesse L. Gurgel,Thomas F. Kenney,Jane L. Burns,William R. Baker +7 more
TL;DR: FTI is a broad-spectrum antibiotic combination with high activity in vitro and in vivo and could be a potential treatment for respiratory infections caused by Gram-positive and Gram-negative aerobic bacteria.
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Studies on hepatoprotective, antispasmodic and calcium antagonist activities of the aqueous-methanol extract of Achillea millefolium.
TL;DR: Results indicate that the crude extract of Achillea millefolium exhibits a hepatoprotective effect, which may be partly attributed to its observed calcium channel blocking activity.
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Use of peak systolic strain as an index of regional left ventricular function: comparison with tissue Doppler velocity during dobutamine stress and myocardial ischemia.
Guy Armstrong,Agnes Pasquet,Agnes Pasquet,Kiyotaka Fukamachi,Kiyotaka Fukamachi,Lisa Cardon,Lisa Cardon,Bjorn Olstad,Bjorn Olstad,Thomas H. Marwick +9 more
TL;DR: Epsilon (s) appears to respond to local ischemia earlier than MDV, perhaps because it is a more local measure, and may prove to be an accurate parameter for the clinical recognition of regional ischemIA.
References
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Oxidants, antioxidants, and the degenerative diseases of aging
TL;DR: It is argued that this damage to DNA, protein, and lipid is a major contributor to aging and to degenerative diseases of aging such as cancer, cardiovascular disease, immune-system decline, brain dysfunction, and cataracts.
Journal ArticleDOI
Guide for the Care and Use of Laboratory Animals
TL;DR: The Guide for the Care and Use of Laboratory Animals by the Institute for Laboratory Animal Research (ILAR) of the National Research Council in the USA, is well known among most individuals involved in laboratory animal care and use and the overall intention is to support the readers to build a programme which creates a system of selfregulation and regulatory oversight.