Journal ArticleDOI
Guideline for the laboratory diagnosis of functional iron deficiency.
TLDR
One form of FID, found in some subjects treated with erythropoiesis-stimulating agents (ESAs), has been the subject of numerous studies following the widespread use of these agents, especially in subjects with chronic kidney disease (CKD).Abstract:
Functional iron deficiency (FID) is a state in which there is insufficient iron incorporation into erythroid precursors in the face of apparently adequate body iron stores, as defined by the presence of stainable iron in the bone marrow together with a serum ferritin value within normal limits (Macdougall et al, 1989). In its broadest sense this definition encompasses the partial block in iron transport to the erythroid marrow seen in subjects with infectious, inflammatory and malignant diseases, and is a major component of the anaemia of chronic disease (ACD). One form of FID, found in some subjects treated with erythropoiesis-stimulating agents (ESAs), has been the subject of numerous studies following the widespread use of these agents, especially in subjects with chronic kidney disease (CKD).read more
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Hepcidin and GDF-15 are potential biomarkers of iron deficiency anaemia in chronic kidney disease patients in South Africa
Aishatu Muhammad Nalado,Aishatu Muhammad Nalado,Gbenga Olorunfemi,Therese Dix-Peek,Caroline Dickens,Lungile Khambule,Tracy Snyman,Graham Paget,Johnny Mahlangu,Raquel Duarte,Jaya A. George,Saraladevi Naicker +11 more
TL;DR: Serum GDF-15 is a potential biomarker of absolute IDA, while hepcidin levels can predict functional IDA among CKD patients, according to multiple linear regression modelling.
NCCN Guidelines Version 3.2014 Panel Members Cancer- and Chemotherapy-Induced Anemia
George M. Rodgers,Jeffrey A. Gilreath,Morey A. Blinder,David Cella,Robert H. Lurie,Benjamin Djulbegovic,Eric H. Kraut,Marisa B. Marques,Ursula A. Matulonis,Michael Millenson,Denise K. Reinke,Joseph Rosenthal,Satish Shanbhag,Gerald A. Soff,Richard S. Stein,Gordana Vlahovic,Alva B. Weir +16 more
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Diagnostics and treatment of preoperative anemia
TL;DR: Die vorliegende Übersichtsarbeit stellt wichtige Aspekte der Epidemiologie and prognostischen Bedeutung der präoperativen Anämie, der PhysiologIE and Pathophysiologies der Erythropoese, der Anämiediagnostik and der daraus abgeleiteten Therapieansätze dar and diskutiert die
Journal ArticleDOI
Canine reticulocyte hemoglobin content (RET-He) in different types of iron-deficient erythropoiesis.
Jannika Fuchs,Andreas Moritz,Esther Grußendorf,Jörg Lechner,Felix Neuerer,Rafael Nickel,Thomas Rieker,Claudia Schwedes,Dennis B. DeNicola,James W. Russell,Natali Bauer +10 more
TL;DR: Low RET-He values indicate IDE even in dogs with other CBC variables within the RIs, even though these dogs have been diagnosed with different causes of iron-deficient erythropoiesis.
Déterminants de la pratique du bilan sanguin de routine chez l’adulte sans pathologie chronique connue en médecine générale
TL;DR: In this paper, a qualitative analysis of the determinants of the pratique du bilan sanguin de routine (BSR) in a population of generalistes is presented.
References
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Journal Article
K/DOQI clinical practice guidelines for chronic kidney disease: Evaluation, classification, and stratification
Andrew S. Levey,Josef Coresh,Kline Bolton,Bruce Culleton,Kathy Schiro Harvey,T. Alp Ikizler,Cynda Ann Johnson,Annamaria T. Kausz,Paul L. Kimmel,John W. Kusek,Adeera Levin,Kenneth L. Minaker,Robert Nelson,Helmut G. Rennke,Michael Steffes,Beth Witten,Ronald J. Hogg,Susan Furth,Kevin V. Lemley,Ronald J. Portman,George Schwartz,Joseph Lau,Ethan M Balk,Ronald D. Perrone,Tauqeer Karim,Lara Rayan,Inas Al-Massry,Priscilla Chew,Brad C. Astor,Deirdre De Vine,Garabed Eknoyan,Nathan W. Levin,Sally Burrows-Hudson,William F. Keane,Alan S. Kliger,Derrick Latos,Donna Mapes,Edith Oberley,Kerry Willis,George R. Bailie,Gavin J. Becker,Jerrilynn Burrowes,David Churchill,Allan J. Collins,William Couser,Dick DeZeeuw,Alan Garber,Thomas Golper,Frank A. Gotch,Antonio M. Gotto,Joel W. Greer,Richard H. Grimm,Ramon G. Hannah,Jaime Herrera Acosta,Ronald J. Hogg,Lawrence G. Hunsicker,Michael J. Klag,Saulo Klahr,Caya Lewis,Edmund G. Lowrie,Arthur J. Matas,Sally McCulloch,Maureen Michael,Joseph V. Nally,John M. Newmann,Allen R. Nissenson,Keith Norris,William F. Owen,Thakor G. Patel,Glenda Payne,Rosa A. Rivera-Mizzoni,David A. Smith,Robert A. Star,Theodore Steinman,Fernando Valderrábano,John Walls,Jean Pierre Wauters,Nanette Wenger,Josephine P. Briggs +78 more
TL;DR: In the early 1990s, the National Kidney Foundation (K/DOQI) developed a set of clinical practice guidelines to define chronic kidney disease and to classify stages in the progression of kidney disease.
Journal ArticleDOI
Hepcidin Regulates Cellular Iron Efflux by Binding to Ferroportin and Inducing Its Internalization
Elizabeta Nemeth,Marie S. Tuttle,Julie Powelson,Michael B. Vaughn,Adriana Donovan,Diane M. Ward,Tomas Ganz,Jerry Kaplan +7 more
TL;DR: It is reported that hepcidin bound to ferroportin in tissue culture cells, leading to decreased export of cellular iron and the posttranslational regulation of ferroports by hePCidin may complete a homeostatic loop.
Journal ArticleDOI
KDOQI Clinical Practice Guidelines and Clinical Practice Recommendations for Anemia in Chronic Kidney Disease.
TL;DR: This chapter discusses clinical practice guidelines and recommendations for treatment of anemia in children and adults with Kidney Kidney disease, as well as specific cases of patients with HD-CKD.
Journal ArticleDOI
Revised European best practice guidelines for the management of anaemia in patients with chronic renal failure.
Francesco Locatelli,Pedro Aljama,Peter Bárány,Bernard Canaud,Fernando Carrera,Kai-Uwe Eckardt,Walter H. Hörl,Iain C Macdougal,Alison M. MacLeod,Andrzej Wiecek,Stewart Cameron +10 more
Journal ArticleDOI
Serum transferrin receptor and its ratio to serum ferritin in the diagnosis of iron deficiency.
TL;DR: In anemic patients, TfR measurement is a valuable noninvasive tool for the diagnosis of iron depletion, and offers an attractive alternative to more conventional laboratory tests in the detection of depleted iron stores.