Gut Akkermansia muciniphila ameliorates metabolic dysfunction-associated fatty liver disease by regulating the metabolism of L-aspartate via gut-liver axis.
Yong Rao,Zhi-qi Kuang,Chan Li,Shi-Yao Guo,Yao-Hao Xu,Dan-Dan Zhao,Yu-Tao Hu,Bing-Bing Song,Zhi Jiang,Zhen-Huang Ge,Xi-Yuan Liu,Cheng-Dao Li,Shuo-Bin Chen,Ji-Ming Ye,Zhi-Shu Huang,Yongjun Lu +15 more
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TLDR
Akkermansia muciniphila has been increasingly recognized for its therapeutic potential in treating metabolic disorders, including obesity, diabetes, and metabolicdysfunction-association as discussed by the authors.Abstract:
The gut bacterium Akkermansia muciniphila has been increasingly recognized for its therapeutic potential in treating metabolic disorders, including obesity, diabetes, and metabolicdysfunction-assoc...read more
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Short- and Long-Term Effects of Different Antibiotics on the Gut Microbiota and Cytokines Level in Mice
TL;DR: In this paper , the impact of different types of antibiotics on the gut microbiome and cytokines level of mice was analyzed and the effects of exposure to antibiotics was shown to affect the normal weight gain of mice.
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<i>Akkermansia muciniphila</i> and <i>Bifidobacterium bifidum</i> Prevent NAFLD by Regulating FXR Expression and Gut Microbiota
TL;DR: In this article , Akkermansia muciniphila and Bifidobacterium bifidum alone or in combination were shown to prevent NAFLD, the effects of their action alone and in combination, possible mechanisms, and modulation of the gut microbiota.
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Intestinal Microbiota Participates in the Protective Effect of HO-1/BMMSCs on Liver Transplantation With Steatotic Liver Grafts in Rats
Mengshu Yuan,Ling Lin,Huan Cao,Wei-Ping Zheng,Longlong Wu,Huaiwen Zuo,Xiaorong Tian,Hongli Song +7 more
TL;DR: Hme oxygenase-1-modified bone marrow mesenchymal stem cells have protective effects on steatotic liver grafts and the intestinal barrier function of the recipients and, by improving lipid metabolism and increasing the abundance of butyrate-producing bacteria, the changed intestinal microbiota has a protective effect and prolongs the recipients' survival time.
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Wolfberry enhanced the abundance of Akkermansia muciniphila by YAP1 in mice with acetaminophen‐induced liver injury
Yiwei Liu,Yu Xue,Zhiqin Zhang,Jing-na Ji,Caige Li,Kangning Zheng,Junlan Lu,Yuting Gao,Yi Gong,Yuman Zhang,Xinli Shi +10 more
TL;DR: In this paper , wolfberry was used to increase the abundance of Akkermansia muciniphila in mice colons, which improved the intestinal mucosal barrier and reduced lipopolysaccharide (LPS) content in the liver.
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Bifidobacterium longum 070103 Fermented Milk Improve Glucose and Lipid Metabolism Disorders by Regulating Gut Microbiota in Mice
Tong Jiang,Ying Li,Longyan Li,Tingting Liang,Mingzhu Du,Lingshuang Yang,Juan Yang,Runshi Yang,Huiting Zhao,Moutong Chen,Yu Fei Ding,Jumei Zhang,Juan Wang,Xinqiang Xie,Qingping Wu +14 more
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References
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Cross-talk between Akkermansia muciniphila and intestinal epithelium controls diet-induced obesity
Amandine Everard,Clara Belzer,Lucie Geurts,Janneke P. Ouwerkerk,Céline Druart,Laure B. Bindels,Yves Guiot,Muriel Derrien,Giulio G. Muccioli,Nathalie M. Delzenne,Willem M. de Vos,Willem M. de Vos,Patrice D. Cani +12 more
TL;DR: Substantial insight is provided into the intricate mechanisms of bacterial regulation of the cross-talk between the host and gut microbiota and provides a rationale for the development of a treatment that uses this human mucus colonizer for the prevention or treatment of obesity and its associated metabolic disorders.
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