Human metabolism and elimination of the anthocyanin, cyanidin-3-glucoside: a 13C-tracer study
C. Czank,Aedin Cassidy,Qingzhi Zhang,Douglas J. Morrison,Tom Preston,Paul A. Kroon,Nigel P. Botting,Colin D. Kay +7 more
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TLDR
Anthocyanins are more bioavailable than previously perceived, and their metabolites are present in the circulation for ≤48 h after ingestion, as investigated in humans.About:
This article is published in The American Journal of Clinical Nutrition.The article was published on 2013-05-01 and is currently open access. It has received 492 citations till now. The article focuses on the topics: Metabolite.read more
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Fasting serum hippuric acid is elevated after bilberry (Vaccinium myrtillus) consumption and associates with improvement of fasting glucose levels and insulin secretion in persons at high risk of developing type 2 diabetes
Vanessa D. de Mello,Maria Lankinen,Jaana Lindström,Riitta Puupponen-Pimiä,David E. Laaksonen,Jussi Pihlajamäki,Marko Lehtonen,Matti Uusitupa,Jaakko Tuomilehto,Jaakko Tuomilehto,Jaakko Tuomilehto,Marjukka Kolehmainen,Riitta Törrönen,Kati Hanhineva +13 more
TL;DR: In this paper, the authors assessed how serum hippuric acid changes after a bilberry-enriched diet (BB) and another berry diet including strawberries, raspberries and cloudberries (SRC), and how these changes associate with insulin and glucose metabolism.
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Plasma and Urinary Phenolic Profiles after Acute and Repetitive Intake of Wild Blueberry
TL;DR: The results illustrate that blueberry (poly)phenols are absorbed and extensively metabolized by phase II enzymes and by the gut microbiota, leading to a whole array of metabolites that may be responsible for the beneficial effects observed after blueberry consumption.
Journal ArticleDOI
Dietary Black Raspberries Impact the Colonic Microbiome and Phytochemical Metabolites in Mice.
Junnan Gu,Jennifer M. Thomas-Ahner,Ken M. Riedl,Michael T. Bailey,Michael T. Bailey,Yael Vodovotz,Steven J. Schwartz,Steven K. Clinton +7 more
TL;DR: It is demonstrated that microbially produced phytochemical metabolites are present in the colon and systemic circulation where they may exert biological activity.
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Black elderberry extract attenuates inflammation and metabolic dysfunction in diet-induced obese mice
Nicholas Farrell,Gregory H Norris,Julia Ryan,Caitlin M. Porter,Christina Jiang,Christopher N. Blesso +5 more
TL;DR: BEE may have improved some metabolic disturbances present in this mouse model of obesity by lowering serum TAG, inflammatory markers and insulin resistance, and suggesting a pro-fibrogenic phenotype that was less inflammatory in 1·25 %-BEE.
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Effect of protocatechuic acid on insulin responsiveness and inflammation in visceral adipose tissue from obese individuals: possible role for PTP1B.
Paulina Ormazabal,Beatrice Scazzocchio,Rosaria Varì,Carmela Santangelo,Massimo D'Archivio,Gianfranco Silecchia,Annunziata Iacovelli,Claudio Giovannini,Roberta Masella +8 more
TL;DR: Results support the beneficial role of an anthocyanin-rich diet against inflammation and insulin resistance in obesity and restore the insulin responsiveness of OB-VAT by increasing IRS-1 and Akt phosphorylation which could be related with the lower PTP1B activity found in PCA-treated OB- VAT.
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Journal ArticleDOI
Bioavailability and bioefficacy of polyphenols in humans. I. Review of 97 bioavailability studies
TL;DR: Gallic acid and isoflavones are the most well-absorbed polyphenols, followed by catechins, flavanones, and quercetin glucosides, but with different kinetics, and the least well- absorption polyphenol are the proanthocyanidins, the galloylated tea catech ins, andThe anthocyanins.
Journal ArticleDOI
Geometric method for measuring body surface area: A height-weight formula validated in infants, children, and adults†
TL;DR: Estimates of body surface area were made based on measurement of 81 subjects, ranging from premature infants to adults, and closer agreement was obtained with the equations and nomograms of Body, Brody, Faber and Melcher, and Sendroy and Cecchini, although minor deviations were noted in some age ranges.
Journal ArticleDOI
PKSolver: An add-in program for pharmacokinetic and pharmacodynamic data analysis in Microsoft Excel
TL;DR: The PKSolver provided pharmacokinetic researchers with a fast and easy-to-use tool for routine and basic PK and PD data analysis with a more user-friendly interface and its output could be generated in Microsoft Word in the form of an integrated report.
Journal ArticleDOI
Bioavailability and bioefficacy of polyphenols in humans. II. Review of 93 intervention studies
Gary Williamson,Claudine Manach +1 more
TL;DR: It is time to rethink the design of in vitro and in vivo studies, so that these issues are carefully considered, and the length of human intervention studies should be increased, to more closely reflect the long-term dietary consumption of polyphenols.
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Phenol-Explorer: an online comprehensive database on polyphenol contents in foods
V. Neveu,Jara Pérez-Jiménez,F. Vos,V. Crespy,L. du Chaffaut,L. Mennen,Craig Knox,Roman Eisner,Joseph A. Cruz,David S. Wishart,Augustin Scalbert +10 more
TL;DR: Phenol-Explorer is the first comprehensive web-based database on polyphenol content in foods and should help researchers to better understand the role of phytochemicals in the technical and nutritional quality of food, and food manufacturers to develop tailor-made healthy foods.