Human metabolism and elimination of the anthocyanin, cyanidin-3-glucoside: a 13C-tracer study
C. Czank,Aedin Cassidy,Qingzhi Zhang,Douglas J. Morrison,Tom Preston,Paul A. Kroon,Nigel P. Botting,Colin D. Kay +7 more
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TLDR
Anthocyanins are more bioavailable than previously perceived, and their metabolites are present in the circulation for ≤48 h after ingestion, as investigated in humans.About:
This article is published in The American Journal of Clinical Nutrition.The article was published on 2013-05-01 and is currently open access. It has received 492 citations till now. The article focuses on the topics: Metabolite.read more
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Aronia berry inhibits disruption of Caco-2 intestinal barrier function.
TL;DR: Aronia berry, but not its microbiota-derived catabolites improved intestinal barrier function in a cellular model of chronic colonic inflammation and was associated with modulation of tight junction expression.
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Chemopreventive effects of anthocyanins on colorectal and breast cancer: A review.
TL;DR: In this article, a review of the current state of diet anthocyanin research in breast cancer (BC) and colorectal cancer (CRC) animal models but also for up-to-date human studies is presented.
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The role of the gut microbiome in the association between habitual anthocyanin intake and visceral abdominal fat in population-level analysis
Amy Jennings,Manja Koch,Manja Koch,Majken K. Jensen,Majken K. Jensen,Corinna Bang,Jan Kassubek,Hans-Peter Müller,Ute Nöthlings,Andre Franke,Wolfgang Lieb,Aedin Cassidy +11 more
TL;DR: It is suggested that higher microbial diversity and abundance of specific taxa in the Clostridiales order may contribute to the association between higher intake of anthocyanin-rich foods and lower abdominal adipose tissue.
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Pistacia Genus as a Potential Source of Neuroprotective Natural Products
TL;DR: The pharmacology of neurological effects and related molecular mechanisms of the plants belonging to the genus Pistacia and its active constituents, as well as pharmacokinetics aspects, are discussed.
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Systematic Chemical Analysis Approach Reveals Superior Antioxidant Capacity via the Synergistic Effect of Flavonoid Compounds in Red Vegetative Tissues
TL;DR: It is suggested that the synergistic effect of individual flavonoids cooperate in a flavonoid system, thus producing a synergistic antioxidant effect, and the approach used herein can provide insights into the roles of flavonoidal compounds in future studies.
References
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Bioavailability and bioefficacy of polyphenols in humans. I. Review of 97 bioavailability studies
TL;DR: Gallic acid and isoflavones are the most well-absorbed polyphenols, followed by catechins, flavanones, and quercetin glucosides, but with different kinetics, and the least well- absorption polyphenol are the proanthocyanidins, the galloylated tea catech ins, andThe anthocyanins.
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Geometric method for measuring body surface area: A height-weight formula validated in infants, children, and adults†
TL;DR: Estimates of body surface area were made based on measurement of 81 subjects, ranging from premature infants to adults, and closer agreement was obtained with the equations and nomograms of Body, Brody, Faber and Melcher, and Sendroy and Cecchini, although minor deviations were noted in some age ranges.
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PKSolver: An add-in program for pharmacokinetic and pharmacodynamic data analysis in Microsoft Excel
TL;DR: The PKSolver provided pharmacokinetic researchers with a fast and easy-to-use tool for routine and basic PK and PD data analysis with a more user-friendly interface and its output could be generated in Microsoft Word in the form of an integrated report.
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Bioavailability and bioefficacy of polyphenols in humans. II. Review of 93 intervention studies
Gary Williamson,Claudine Manach +1 more
TL;DR: It is time to rethink the design of in vitro and in vivo studies, so that these issues are carefully considered, and the length of human intervention studies should be increased, to more closely reflect the long-term dietary consumption of polyphenols.
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Phenol-Explorer: an online comprehensive database on polyphenol contents in foods
V. Neveu,Jara Pérez-Jiménez,F. Vos,V. Crespy,L. du Chaffaut,L. Mennen,Craig Knox,Roman Eisner,Joseph A. Cruz,David S. Wishart,Augustin Scalbert +10 more
TL;DR: Phenol-Explorer is the first comprehensive web-based database on polyphenol content in foods and should help researchers to better understand the role of phytochemicals in the technical and nutritional quality of food, and food manufacturers to develop tailor-made healthy foods.