Journal ArticleDOI
In vivo, effect of herb (Withania somnifera) on immunomodulatory and antioxidative potential of milk in mice
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TLDR
Findings indicated that aqueous extract of WS is able to enhance immunomodulatory and antioxidative properties of milk.Abstract:
Eighteen healthy male Swiss albino mice of specific weight (25–30g) were randomly divided into three groups of six animals each and given specific diets for a period 28 days. Group A was given normal synthetic diet (NSD) and milk; Group B: NSD and Withania somnifera (WS) extract (0.3%) and Group C: NSD supplemented with milk and WS extract (0.3%). The phagocytic activity of peritoneal macrophages and Immunoglobulin G (lgG) level in mice serum increased significantly in comparison to control group in WS-supplemented groups. The lymphocyte proliferation index did not alter significantly (P < 0.05) in supplemented groups after a period of 28 days. Group B and C showed significantly higher reduced glutathione level and significantly lowered (P < 0.05), carbonyl protein and thiobarbituric acid reactive substances in liver and red blood cells lysates as compared to control. This finding indicated that aqueous extract of WS is able to enhance immunomodulatory and antioxidative properties of milk.read more
Citations
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Journal ArticleDOI
Ashwagandha in brain disorders: A review of recent developments.
TL;DR: The review concludes the results of recent studies on Ashwagandha suggesting its extensive potential as neuroprotective in various brain disorders as supported by preclinical studies, clinical trials and published patents.
Journal ArticleDOI
Euterpe edulis extracts positively modulates the redox status and expression of inflammatory mediators
R. B. Freitas,D. N. Rômulo,G. M. Bianca,C. S. Eliziária,S. A. Murilo,G. F. Luciano,M. L. Luciana,P. Maria do Carmo,V. G. Reggiani,V. L. João Paulo +9 more
TL;DR: In this article, the effects of derivatives from Euterpe spp. fruits on oxidative metabolism and inflammatory mediators were evaluated, and the results indicated that dietary supplementation with extracts of E.edulis has no deleterious effects and may be beneficial, especially for LEDE extracts containing high concentrations of anthocyanin.
Journal ArticleDOI
A comparative study of the antioxidant and ACE inhibitory activities of selected herbal extracts
TL;DR: In this paper, the authors compared and elucidated the antioxidant and ACE inhibitory potential of aqueous extracts of six herbs at different concentrations, viz. Emblica officinalis, Withania somnifera, Hibiscus sabdriffa, Ginkgo biloba, Ocimum sanctum and Allium sativum.
Journal ArticleDOI
Withania somnifera as a phytoherbal growth promoter for broilers farming
M. C. de Oliveira,Youssef A. Attia,Asmaa F. Khafaga,Adel Daifallah Alqurashi,Khalid A. Asiry,Ayman E. Taha,Mohamed E. Abd El-Hack +6 more
TL;DR: In this paper , the authors highlighted the morphological features, distribution, chemical structure, and pharmacological features of Withania somnifera as a growth promoter herb for farming broiler chickens.
Journal ArticleDOI
Phytochemicals of Withania somnifera as a Future Promising Drug against SARS-CoV-2: Pharmacological Role, Molecular Mechanism, Molecular Docking Evaluation, and Efficient Delivery
Suaidah Ramli,Yuan Seng Wu,Kalaivani Batumalaie,Rhanye Mac Guad,Ker Woon Choy,Ashok Kumar,Subash C. B. Gopinath,Md. Moklesur Rahman Sarker,Vetriselvan Subramaniyan,Mahendran Sekar,Neeraj Kumar Fuloria,Shivkanya Fuloria,Suresh V. Chinni,Gobinath Ramachawolran +13 more
TL;DR: In this paper , a review focused on the updated testing of therapeutic efficacy and associated molecular mechanisms of WS extracts and their phytochemicals against SARS-CoV-2 infection in preclinical and clinical studies with the aim to develop a long-term solution against COVID-19.
References
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Journal Article
The Effects of Plant Flavonoids on Mammalian Cells:Implications for Inflammation, Heart Disease, and Cancer
TL;DR: Western medicine has not yet used flavonoids therapeutically, even though their safety record is exceptional, and suggestions are made where such possibilities may be worth pursuing.