Journal ArticleDOI
Metabolic engineering of yeast for production of fuels and chemicals
TLDR
Recent scientific progress in metabolic engineering of S. cerevisiae for the production of bioethanol, advanced biofuels, and chemicals is reviewed.About:
This article is published in Current Opinion in Biotechnology.The article was published on 2013-06-01. It has received 292 citations till now.read more
Citations
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Journal ArticleDOI
A thermo- and toxin-tolerant kefir yeast for biorefinery and biofuel production
Jui-Jen Chang,Jui-Jen Chang,Cheng-Yu Ho,Chi-Tang Mao,Chi-Tang Mao,Nathan Barham,Yu-Rong Huang,Feng-Ju Ho,Yueh-Chin Wu,Yu-Han Hou,Ming-Che Shih,Wen-Hsiung Li,Chieh-Chen Huang +12 more
TL;DR: It was shown that a novel dual-microbe co-culture system of Bacillus subtilis and KY3–NpaBGS can be employed for bioethanol production from cellulosic material and has a high potential to be a good host for biorefinery.
Book ChapterDOI
Cell-Free Synthetic Systems for Metabolic Engineering and Biosynthetic Pathway Prototyping
Journal ArticleDOI
The Evaluation of Bioremediation Potential of a Yeast Collection Isolated from Composting
Bianca Trama,João Daniel Santos Fernandes,Geórgia Labuto,Julio Cezar Franco de Oliveira,Cristina Viana-Niero,Renata C. Pascon,Marcelo A. Vallim +6 more
TL;DR: Findings confirm the initial hypothesis that the Sao Paulo Zoo composting is the source for diverse yeasts species with biotechnological application potential and search for yeast isolates capable of utilizing n-hexadecane as a primary carbon source and those able to tolerate high concentration of lead.
Journal ArticleDOI
Improved ethyl caproate production of Chinese liquor yeast by overexpressing fatty acid synthesis genes with OPI1 deletion
TL;DR: Overall, this study offers a promising platform for the development of pure yeast culture fermentation of Chinese strong aromatic liquor without the use of a mud pit.
BookDOI
Genetic Transformation Systems in Fungi, Volume 2
TL;DR: Anastomosis and Heterokaryon Formation, Induction of the Sexual Cycle in Filamentous Ascomycetes, and RNAi-mediated Gene Silencing in the Beta-lactam Producers Fungi are studied.
References
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Journal ArticleDOI
Opportunities and challenges for a sustainable energy future
Steven Chu,Arun Majumdar +1 more
TL;DR: This Perspective provides a snapshot of the current energy landscape and discusses several research and development opportunities and pathways that could lead to a prosperous, sustainable and secure energy future for the world.
Journal ArticleDOI
Production of the antimalarial drug precursor artemisinic acid in engineered yeast
Dae-Kyun Ro,Eric M. Paradise,Mario Ouellet,Karl Fisher,Karyn L. Newman,John M. Ndungu,Ho Kimberly,Eachus Rachel,Timothy S. Ham,James Kirby,Michelle C. Y. Chang,Sydnor T. Withers,Yoichiro Shiba,Richmond Sarpong,Jay D. Keasling +14 more
TL;DR: The engineering of Saccharomyces cerevisiae to produce high titres (up to 100 mg l-1) of artemisinic acid using an engineered mevalonate pathway, amorphadiene synthase, and a novel cytochrome P450 monooxygenase from A. annua that performs a three-step oxidation of amorpha-4,11-diene to art Artemisinic acid.
Journal ArticleDOI
Osmotic Stress Signaling and Osmoadaptation in Yeasts
TL;DR: An integrated understanding of osmoadaptation requires not only knowledge of the function of many uncharacterized genes but also further insight into the time line of events, their interdependence, their dynamics, and their spatial organization as well as the importance of subtle effects.
Journal ArticleDOI
Microbial production of fatty-acid-derived fuels and chemicals from plant biomass
Eric J. Steen,Yisheng Kang,Gregory Bokinsky,Zhihao Hu,Andreas W. Schirmer,Amy McClure,Stephen B. del Cardayre,Jay D. Keasling +7 more
TL;DR: The engineering of Escherichia coli is demonstrated to produce structurally tailored fatty esters (biodiesel), fatty alcohols, and waxes directly from simple sugars, a step towards producing these compounds directly from hemicellulose, a major component of plant-derived biomass.
Journal ArticleDOI
Microbial Biosynthesis of Alkanes
TL;DR: The discovery of an alkane biosynthesis pathway in cyanobacteria that converts intermediates of fatty acid metabolism to alkanes and alkenes is described and is likely to be a valuable tool in the production of biofuels.
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