Journal ArticleDOI
Metabolic engineering of yeast for production of fuels and chemicals
TLDR
Recent scientific progress in metabolic engineering of S. cerevisiae for the production of bioethanol, advanced biofuels, and chemicals is reviewed.About:
This article is published in Current Opinion in Biotechnology.The article was published on 2013-06-01. It has received 292 citations till now.read more
Citations
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Metabolic Engineering and Molecular Tool Development in Yeast for Production of Bulk Chemicals
TL;DR: The publicly available EasyClone-MarkerFree vector suite allows for facile and highly standardized genome engineering, and should be of particular interest to researchers working on yeast chassis with limited markers available.
Journal ArticleDOI
Keragaman Jenis Khamir Penghasil Etanol yang Diisolasi dari Makanan Fermentasi di Kepulauan Riau
I Nyoman Sumerta,Atit Kanti +1 more
TL;DR: Yeast diversity in Indonesian fermented foods that can produce ethanol was revealed and 8 yeast species were found belong to Ascomycetous and grouped into 5 clades which are able to produce ethanol.
Dissertation
Exploring Yeast as a Cell Factory for the Production of Carboxylic Acids and Derivatives
TL;DR: A aerobic production of PHB from xylose was achieved in S. cerevisiae through the engineering of an optimized xylOSE oxido-reducing pathway and the expression of the genes involved in the PHB-producing pathway from the bacterium Cupriavidus necator, revealing novel routes for their bio-production and for further optimization studies.
Book ChapterDOI
Kluyveromyces marxianus as a Platform in Synthetic Biology for the Production of Useful Materials
Noppon Lertwattanasakul,Mochamad Nurcholis,Nadchanok Rodrussamee,Tomoyuki Kosaka,Masayuki Murata,Mamoru Yamada +5 more
Book ChapterDOI
Present status and future prospect of genetic and metabolic engineering for biofuels from lignocellulosic biomass
TL;DR: More detailed research is needed to use biofuels as a more mainstream product for meeting the requirement of energy production and use.
References
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Journal ArticleDOI
Opportunities and challenges for a sustainable energy future
Steven Chu,Arun Majumdar +1 more
TL;DR: This Perspective provides a snapshot of the current energy landscape and discusses several research and development opportunities and pathways that could lead to a prosperous, sustainable and secure energy future for the world.
Journal ArticleDOI
Production of the antimalarial drug precursor artemisinic acid in engineered yeast
Dae-Kyun Ro,Eric M. Paradise,Mario Ouellet,Karl Fisher,Karyn L. Newman,John M. Ndungu,Ho Kimberly,Eachus Rachel,Timothy S. Ham,James Kirby,Michelle C. Y. Chang,Sydnor T. Withers,Yoichiro Shiba,Richmond Sarpong,Jay D. Keasling +14 more
TL;DR: The engineering of Saccharomyces cerevisiae to produce high titres (up to 100 mg l-1) of artemisinic acid using an engineered mevalonate pathway, amorphadiene synthase, and a novel cytochrome P450 monooxygenase from A. annua that performs a three-step oxidation of amorpha-4,11-diene to art Artemisinic acid.
Journal ArticleDOI
Osmotic Stress Signaling and Osmoadaptation in Yeasts
TL;DR: An integrated understanding of osmoadaptation requires not only knowledge of the function of many uncharacterized genes but also further insight into the time line of events, their interdependence, their dynamics, and their spatial organization as well as the importance of subtle effects.
Journal ArticleDOI
Microbial production of fatty-acid-derived fuels and chemicals from plant biomass
Eric J. Steen,Yisheng Kang,Gregory Bokinsky,Zhihao Hu,Andreas W. Schirmer,Amy McClure,Stephen B. del Cardayre,Jay D. Keasling +7 more
TL;DR: The engineering of Escherichia coli is demonstrated to produce structurally tailored fatty esters (biodiesel), fatty alcohols, and waxes directly from simple sugars, a step towards producing these compounds directly from hemicellulose, a major component of plant-derived biomass.
Journal ArticleDOI
Microbial Biosynthesis of Alkanes
TL;DR: The discovery of an alkane biosynthesis pathway in cyanobacteria that converts intermediates of fatty acid metabolism to alkanes and alkenes is described and is likely to be a valuable tool in the production of biofuels.
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