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Journal ArticleDOI

Metabolic engineering of yeast for production of fuels and chemicals

TLDR
Recent scientific progress in metabolic engineering of S. cerevisiae for the production of bioethanol, advanced biofuels, and chemicals is reviewed.
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This article is published in Current Opinion in Biotechnology.The article was published on 2013-06-01. It has received 292 citations till now.

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Journal ArticleDOI

Co-production of 11α-hydroxyprogesterone and ethanol using recombinant yeast expressing fungal steroid hydroxylases

TL;DR: The data presented demonstrate how recombinant yeast could find application in rural biorefinery processes where co-production of value-added products (11α-hydroxyprogesterone and ethanol) from novel feedstocks is an emergent and attractive possibility.
Journal ArticleDOI

Enhanced Bioconversion of Cellobiose by Industrial Saccharomyces cerevisiae Used for Cellulose Utilization.

TL;DR: It is proved that fastcellobiose utilization enhanced ethanol production by reducing cellobiose accumulation during SSF at high temperature by improving the cellobiOSE utilization of the engineered yeast strain.
Book ChapterDOI

Fungal Biotechnology in Space: Why and How?

TL;DR: It is proposed here that fungi can become important cell factories for life in space, especially regarding the filamentous fungus Aspergillus niger as the cutting-edge must-have for space travel in the twenty-first century and beyond.
Journal ArticleDOI

Utility of Feed Enzymes and Yeast Derivatives in Ameliorating Deleterious Effects of Coccidiosis on Intestinal Health and Function in Broiler Chickens.

TL;DR: There is evidence feed enzymes and yeast derivatives could complement strategies for maintaining intestinal function to bolster growth performance in broilers compromised with coccidiosis, and further refinement research is warranted to address inconsistencies in responses and commercial application.
References
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Journal ArticleDOI

Opportunities and challenges for a sustainable energy future

TL;DR: This Perspective provides a snapshot of the current energy landscape and discusses several research and development opportunities and pathways that could lead to a prosperous, sustainable and secure energy future for the world.
Journal ArticleDOI

Production of the antimalarial drug precursor artemisinic acid in engineered yeast

TL;DR: The engineering of Saccharomyces cerevisiae to produce high titres (up to 100 mg l-1) of artemisinic acid using an engineered mevalonate pathway, amorphadiene synthase, and a novel cytochrome P450 monooxygenase from A. annua that performs a three-step oxidation of amorpha-4,11-diene to art Artemisinic acid.
Journal ArticleDOI

Osmotic Stress Signaling and Osmoadaptation in Yeasts

TL;DR: An integrated understanding of osmoadaptation requires not only knowledge of the function of many uncharacterized genes but also further insight into the time line of events, their interdependence, their dynamics, and their spatial organization as well as the importance of subtle effects.
Journal ArticleDOI

Microbial production of fatty-acid-derived fuels and chemicals from plant biomass

TL;DR: The engineering of Escherichia coli is demonstrated to produce structurally tailored fatty esters (biodiesel), fatty alcohols, and waxes directly from simple sugars, a step towards producing these compounds directly from hemicellulose, a major component of plant-derived biomass.
Journal ArticleDOI

Microbial Biosynthesis of Alkanes

TL;DR: The discovery of an alkane biosynthesis pathway in cyanobacteria that converts intermediates of fatty acid metabolism to alkanes and alkenes is described and is likely to be a valuable tool in the production of biofuels.
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