Journal ArticleDOI
Nanomaterials at work in biomedical research.
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TLDR
With some nanomaterial-based medicines having entered the marketplace, and more on the verge of doing so, nanomedicine is expected to become an exciting playground for chemists and material scientists.Abstract:
With some nanomaterial-based medicines having entered the marketplace, and more on the verge of doing so, nanomedicine is expected to become an exciting playground for chemists and material scientists.read more
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Antibacterial properties of nanoparticles.
Mohammad Javad Hajipour,Katharina M. Fromm,Ali Akbar Ashkarran,Dorleta Jimenez de Aberasturi,Dorleta Jimenez de Aberasturi,Idoia Ruiz de Larramendi,Teofilo Rojo,Vahid Serpooshan,Wolfgang J. Parak,Morteza Mahmoudi +9 more
TL;DR: This review focuses on the properties and applications of inorganic nanostructured materials and their surface modifications, with good antimicrobial activity, and the role of different NP materials.
Journal ArticleDOI
Towards a definition of inorganic nanoparticles from an environmental, health and safety perspective
Mélanie Auffan,Jérôme Rose,Jérôme Rose,Jean-Yves Bottero,Jean-Yves Bottero,Gregory V. Lowry,Gregory V. Lowry,Jean-Pierre Jolivet,Jean-Pierre Jolivet,Mark R. Wiesner +9 more
TL;DR: It is argued that evidence for novel size-dependent properties alone, rather than particle size, should be the primary criterion in any definition of nanoparticles when making decisions about their regulation for environmental, health and safety reasons.
Journal ArticleDOI
A Molecular Imaging Primer: Modalities, Imaging Agents, and Applications
TL;DR: This review of molecular imaging of intact living subjects focuses specifically on small molecules, peptides, aptamers, engineered proteins, and nanoparticles and cites examples of how molecular imaging is being applied in oncology, neuroscience, cardiology, gene therapy, cell tracking, and theranostics.
Journal ArticleDOI
Computer simulation of the translocation of nanoparticles with different shapes across a lipid bilayer
Kai Yang,Yu-qiang Ma,Yu-qiang Ma +2 more
TL;DR: Using computer simulations, this work investigates the physical translocation processes of nanoparticles with different shapes and volumes and finds that the shape anisotropy and initial orientation of the particle are crucial to the nature of the interaction between the particle and lipid bilayer.
Journal ArticleDOI
Nanoparticulate functional materials.
Helmut Goesmann,Claus Feldmann +1 more
TL;DR: Nanoparticulate functional materials offer manifold perspectives for the increasing miniaturization and complexity of technical developments, and fundamentally novel forms and structures of materials, such as nanocontainers and supercrystals.
References
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Journal ArticleDOI
Biosensing with plasmonic nanosensors
TL;DR: This paper introduces the localized surface plasmon resonance (LSPR) sensor and describes how its exquisite sensitivity to size, shape and environment can be harnessed to detect molecular binding events and changes in molecular conformation.
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In vivo cancer targeting and imaging with semiconductor quantum dots
TL;DR: Sensitive and multicolor fluorescence imaging of cancer cells under in vivo conditions are achieved and a whole-body macro-illumination system with wavelength-resolved spectral imaging is integrated for efficient background removal and precise delineation of weak spectral signatures.
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Nanoparticle-mediated cellular response is size-dependent
TL;DR: It is shown that gold and silver nanoparticles coated with antibodies can regulate the process of membrane receptor internalization and show that nanoparticles should no longer be viewed as simple carriers for biomedical applications, but can also play an active role in mediating biological effects.
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Artificially engineered magnetic nanoparticles for ultra-sensitive molecular imaging.
Jae Hyun Lee,Yong Min Huh,Young-wook Jun,Jung Wook Seo,Jung Tak Jang,Ho Taek Song,Sungjun Kim,Eun Jin Cho,Ho-Geun Yoon,Jin Suck Suh,Jinwoo Cheon +10 more
TL;DR: These magnetism-engineered iron oxide (MEIO) nanoprobes, when conjugated with antibodies, showed enhanced magnetic resonance imaging (MRI) sensitivity for the detection of cancer markers compared with probes currently available and could enhance the ability to visualize other biological events critical to diagnostics and therapeutics.
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Mechanistic study on the replacement reaction between silver nanostructures and chloroauric acid in aqueous medium.
Yugang Sun,Younan Xia +1 more
TL;DR: This work has enabled us to prepare metal nanostructures with controllable geometric shapes and structures, and thus optical properties (for example, the surface plasmon resonance peaks could be readily shifted from 500 to 1200 nm by controlling the ratio between Ag and HAuCl(4)).