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Proceedings ArticleDOI

New ISFET interface circuits with noise reduction capability

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TLDR
In this paper, three different noise reduction techniques for ISFET readout configuration and their comparison is presented, and it is found that the interface circuits are able to compensate the noise to a great extent by compensation of noise by differential techniques (Implemented in LabVIEW environment and with OPAMP based circuit) and compensation by Wheatstone bridge method.
Abstract
In this paper three different noise reduction techniques for Ion Sensitive Field Effect Transistor (ISFET) readout configuration and their comparison is presented. The proposed circuit configurations are immune to the noise generated from the ISFET sensory system and particularly to the low frequency pH dependent 1/f electrochemical noise. The methods used under these studies are- Compensation of noise by differential techniques (Implemented in LabVIEW environment and with OPAMP based circuit) and compensation by Wheatstone bridge method. Here two identical commercial ISFET sensors from Microsens were used. The statistical and frequency analysis of the data generated by the proposed methods were compared for different pH value ranging from pH-2 to pH 10 under room temperature, and it is found that the interface circuits are able to compensate the noise to a great extent.

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Citations
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Journal ArticleDOI

ISFETs in CMOS and Emergent Trends in Instrumentation: A Review

TL;DR: In this paper, the authors present a review of the state-of-the-art in terms of device and early readout circuity for ion-sensitive field effect transistors (ISFETs).
Journal ArticleDOI

Signal and Noise of Schottky-Junction Parallel Silicon Nanowire Transducers for Biochemical Sensing

TL;DR: In this article, the authors investigated the signal-to-noise behavior of parallel arrays of silicon nanowire transistors with intruded Ni silicide contacts and found that the smallest input referred noise level is obtained when operating the device directly at the threshold voltage.
Journal ArticleDOI

Drift Compensation for pH IsFET Sensor Using NARX Neural Networks

TL;DR: A Nonlinear Autoregressive Neural Network (NARX) to predict the sensor error of IsFET pH drift with accuracy over the long period of time and the Bayesian Regularization backpropagation was used as network training function.
Proceedings ArticleDOI

A ROIC for Mn(TPP)Cl-DOP-THF-Polyhema PVC membrane modified n-channel Si3N4 ISFET sensitive to histamine

TL;DR: The development of a ROIC specifically to integrate with a Mn(TPP)Cl-DOP-THF-Polyhema PVC membrane modified n-channel Si3N4 ISFET to display the histamine concentration is concerns.
References
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Journal ArticleDOI

Thirty years of ISFETOLOGY: What happened in the past 30 years and what may happen in the next 30 years

TL;DR: In this paper, the development of ISFETs in an historical setting, but not limited to that, is described, based on the development regarding the theory, the technology, the instrumentation and the experience with many specific applications, also future projects are defined, such as concerning cell acidification, this paperET biasing and a complete new range of FET sensors based on local pressure induction by (bio)chemical interaction with immobilised charged molecules (hydrogels).
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Development, Operation, and Application of the Ion-Sensitive Field-Effect Transistor as a Tool for Electrophysiology

TL;DR: A new solid-state device has been developed that makes it possible to measure ion activities without using a reference electrode and has the properties of both a glass electrode and a field-effect transistor.
Journal ArticleDOI

Mutual compensation of mobility and threshold voltage temperature effects with applications in CMOS circuits

TL;DR: In this paper, the conditions under which this effect occurs, and stability of this bias point are investigated, and verified experimentally investigating the temperature behavior of a simple voltage reference circuit realized in 0.35 /spl mu/m CMOS process.
Journal ArticleDOI

Comprehensive study of noise processes in electrode electrolyte interfaces

TL;DR: In this article, a general circuit model is derived for the electrical noise of electrode-electrolyte systems, with emphasis on its implications for electrochemical sensors, and the noise power spectral densities associated with all noise sources introduced in the model are also analytically calculated.
Journal ArticleDOI

Study on the temperature effect, hysteresis and drift of pH-ISFET devices based on amorphous tungsten oxide

TL;DR: In this paper, the drift, hysteresis and temperature effect of ISFET devices have been studied, and the I-V curves of a-WO3 gate is obtained at different temperatures and the pH sensitivities were calculated in the acid buffer solutions.
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