Journal ArticleDOI
Picornavirus and enterovirus diversity with associated human diseases
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TLDR
The Enterovirus genus is a prototype example of the Picornaviridae heterogeneity at both genetic and phenotypic levels and better characterization of these ubiquitous human pathogens may help to develop vaccines or antiviral treatments and to monitor the emergence of new strains.Citations
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Enterovirus detection and serotyping of fecal material collected from three children living on the outskirts of Belém city, Amazon region, Brazil, during the first 3 years of life (1983-1986).
Carla Rafaela Monteiro Coutinho,Jones Anderson Monteiro Siqueira,Raiana Scerni Machado,Renato da Silva Bandeira,James Lima Ferreira,Jainara Cristina dos Santos Alves,Yvone Benchimol Gabbay,Fernando Neto Tavares +7 more
TL;DR: A high circulation and serotype diversity of EV in fecal samples, collected over 30 years ago, endorsed the evaluation of important points of the epidemiology of these viruses, such as the presence of coinfection and reinfection of the same individual by different circulating serotypes.
Journal ArticleDOI
High Prevalence of Coinfecting Enteropathogens in Suspected Rotavirus Vaccine Breakthrough Cases.
Ceren Simsek,Mandy Bloemen,Daan Jansen,Leen Beller,Patrick Descheemaeker,Marijke Reynders,Marc Van Ranst,Jelle Matthijnssens +7 more
TL;DR: This paper investigated suspected rotavirus vaccine breakthrough cases using next-generation sequencing (NGS)-based viral metagenomics and a panel of semiquantitative reverse transcription-PCR (RT-qPCR) (n) targeting known enteric pathogens.
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Aqueous extracts of Syzygium brazzavillense can inhibit the infection with coxsackievirus B4 in vitro.
Francis Badia-Boungou,Famara Sane,Enagnon Kazali Alidjinou,Thierry Hennebelle,Vincent Roumy,Adolphe Christian Ngakegni-Limbili,Etienne Nguimbi,Donatien Moukassa,Ange Antoine Abena,Didier Hober +9 more
TL;DR: Aqueous extracts of Syzygium brazzavillense can inhibit the infection with CVB4 and other enteroviruses in vitro, and is helpful to combat enterovirus infections.
Journal ArticleDOI
Serological detection and analysis of anti-VP1 responses against various enteroviruses (EV) (EV-A, EV-B and EV-C) in Chinese individuals.
Caixia Gao,Yingying Ding,Peng Zhou,Jiaojiao Feng,Baohua Qian,Ziyu Lin,Lili Wang,Jinhong Wang,Chunyan Zhao,Xiangyu Li,Ming-Mei Cao,Heng Peng,Bing Rui,Wei Pan +13 more
TL;DR: Detailed information of the serological prevalence of human antibody responses against the VP1 of EV-A, B and C viruses is described, which could be helpful for understanding of the ubiquity of EV infections and for identifying an effective approach for seroepidemiological surveillance based on ELISA.
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Persistence of Coxsackievirus B4 in Pancreatic β Cells Disturbs Insulin Maturation, Pattern of Cellular Proteins, and DNA Methylation
Magloire Pandoua Nekoua,Antoine Bertin,Famara Sane,Jean-Pascal Gimeno,Isabelle Fournier,Michel Salzet,Ilka Engelmann,Enagnon Kazali Alidjinou,Didier Hober +8 more
TL;DR: In this article, the authors investigated the persistence and its consequences in insulin-producing pancreatic β cells and found that persistent infection of INS-1 cells with CV-B4 had a deep impact on these cells, especially on insulin metabolism.
References
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Book
Virus taxonomy: classification and nomenclature of viruses. Seventh report of the International Committee on Taxonomy of Viruses.
TL;DR: This report builds on the accumulated taxonomic construction of the eight previous reports dating back to 1971 and records the proceedings of the Committee since publication of the last report in 2005.
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Community study of role of viral infections in exacerbations of asthma in 9-11 year old children.
Sebastian L. Johnston,Philip Pattemore,G. Sanderson,Sandra Smith,F Lampe,Lynn Josephs,P. Symington,S. O'Toole,S. H. Myint,D. A. J. Tyrrell +9 more
TL;DR: This study supports the hypothesis that upper respiratory viral infections are associated with 80-85% of asthma exacerbations in school age children.
Journal ArticleDOI
Mutation rates among RNA viruses
John W. Drake,John J. Holland +1 more
TL;DR: This work describes a simple relation between ribovirus mutation frequencies and mutation rates, applies it to the best (albeit far from satisfactory) available data, and observes a central value for the mutation rate per genome per replication of micro(g) approximately 0.76.
Journal ArticleDOI
Virology, epidemiology, pathogenesis, and control of enterovirus 71.
Tom Solomon,Tom Solomon,Penny Lewthwaite,David Perera,Mary Jane Cardosa,Peter McMinn,Mong How Ooi,Mong How Ooi +7 more
TL;DR: Enterovirus 71 is a major public health issue across the Asia-Pacific region and beyond, with new outbreaks occurring across Asia in regular cycles, and virus gene subgroups seem to differ in clinical epidemiological properties.