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Picornavirus and enterovirus diversity with associated human diseases
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TLDR
The Enterovirus genus is a prototype example of the Picornaviridae heterogeneity at both genetic and phenotypic levels and better characterization of these ubiquitous human pathogens may help to develop vaccines or antiviral treatments and to monitor the emergence of new strains.Citations
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Complete genome sequence of a coxsackievirus A16 strain, isolated from a fatal case in Shenzhen, southern China, in 2014.
TL;DR: The complete genome sequence of a coxsackievirus A16 strain from a fatal case in Shenzhen, southern China, in 2014 was determined and the strain was assigned to subgenotype B1b based on phylogenetic analysis of the VP1 gene.
Journal ArticleDOI
High Diversity of Human Non-Polio Enterovirus Serotypes Identified in Contaminated Water in Nigeria.
Manasi Majumdar,Dimitra Klapsa,Thomas Wilton,Erika Bujaki,Maria Dolores Fernandez-Garcia,Temitope Oluwasegun Cephas Faleye,Adefunke Olufunmilayo Oyero,Moses Olubusuyi Adewumi,Kader Ndiaye,Johnson Adekunle Adeniji,Javier Martin +10 more
TL;DR: In this article, the authors used a recently developed molecular method to investigate the presence of EV in eight samples collected in 2017-2018 from water streams contaminated by drainage channels in three different locations in Nigeria.
Journal ArticleDOI
Therapeutic targets for enterovirus infections.
TL;DR: This review summarizes the recent findings of compounds and tools targeting the enteroviruses and host cell molecules that are crucial for virus infection and states the modern methods to find new targets and tools that help to understand the mechanisms of action.
Journal ArticleDOI
Enteroviruses and Rhinoviruses: Molecular Epidemiology of the Most Influenza-Like Illness Associated Viruses in Senegal
Amary Fall,Ndongo Dia,Ousmane Kebe,Fatoumata Diene Sarr,Davy Evrard Kiori,El Hadj Abdoul Khadir Cisse,Sara Sy,Déborah Goudiaby,Vincent Richard,Ousmane M. Diop,Mbayame Ndiaye Niang +10 more
TL;DR: The results suggest strong year-round respiratory picornavirus activity in children up to 5 years of age in Senegal over a 3-year surveillance period.
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Molecular epidemiology of enteroviruses associated with severe hand, foot and mouth disease in Shenzhen, China, 2014-2018.
Long Chen,Shao-Jian Xu,Xiang-Jie Yao,Hong Yang,Hailong Zhang,Jun Meng,Han-Ri Zeng,Xu-He Huang,Renli Zhang,Yaqing He +9 more
TL;DR: EV-A71 is still the main pathogen causing severe HFMD, although other EV types can also cause severe complications, including coxsackievirus A6 and CVA10.
References
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Book
Virus taxonomy: classification and nomenclature of viruses. Seventh report of the International Committee on Taxonomy of Viruses.
TL;DR: This report builds on the accumulated taxonomic construction of the eight previous reports dating back to 1971 and records the proceedings of the Committee since publication of the last report in 2005.
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Community study of role of viral infections in exacerbations of asthma in 9-11 year old children.
Sebastian L. Johnston,Philip Pattemore,G. Sanderson,Sandra Smith,F Lampe,Lynn Josephs,P. Symington,S. O'Toole,S. H. Myint,D. A. J. Tyrrell +9 more
TL;DR: This study supports the hypothesis that upper respiratory viral infections are associated with 80-85% of asthma exacerbations in school age children.
Journal ArticleDOI
Mutation rates among RNA viruses
John W. Drake,John J. Holland +1 more
TL;DR: This work describes a simple relation between ribovirus mutation frequencies and mutation rates, applies it to the best (albeit far from satisfactory) available data, and observes a central value for the mutation rate per genome per replication of micro(g) approximately 0.76.
Journal ArticleDOI
Virology, epidemiology, pathogenesis, and control of enterovirus 71.
Tom Solomon,Tom Solomon,Penny Lewthwaite,David Perera,Mary Jane Cardosa,Peter McMinn,Mong How Ooi,Mong How Ooi +7 more
TL;DR: Enterovirus 71 is a major public health issue across the Asia-Pacific region and beyond, with new outbreaks occurring across Asia in regular cycles, and virus gene subgroups seem to differ in clinical epidemiological properties.