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Picornavirus and enterovirus diversity with associated human diseases
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TLDR
The Enterovirus genus is a prototype example of the Picornaviridae heterogeneity at both genetic and phenotypic levels and better characterization of these ubiquitous human pathogens may help to develop vaccines or antiviral treatments and to monitor the emergence of new strains.Citations
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Salivary anti-coxsackievirus-B4 neutralizing activity and pattern of immune parameters in patients with type 1 diabetes: a pilot study
Magloire Pandoua Nekoua,Magloire Pandoua Nekoua,Akadiri Yessoufou,Enagnon Kazali Alidjinou,Francis Badia-Boungou,Kabirou Moutairou,Famara Sane,Didier Hober +7 more
TL;DR: There was an association between saliva anti-CV-B4 activity, down-regulation of IFN-γ and B cell expansion in peripheral blood of T1D patients.
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Distribution of enterovirus genotypes detected in clinical samples in Hungary, 2010-2018.
TL;DR: The ability of EVs to cause severe infections in sporadic cases and regular outbreaks highlight the importance of continued monitoring of circulating EV types.
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Enteroviruses in blood of patients with type 1 diabetes detected by integrated cell culture and reverse transcription quantitative real-time PCR.
Enagnon Kazali Alidjinou,Famara Sane,Christine Lefevre,Agathe Baras,Ilham Moumna,Ilka Engelmann,Marie-Christine Vantyghem,Didier Hober +7 more
TL;DR: Integrated cell culture and reverse transcription real-time PCR can improve the detection rate of EV in blood samples of patients with T1D and can be useful to investigate further the relationship between EV and the disease.
Journal ArticleDOI
Defining the Enterovirus Diversity Landscape of a Fecal Sample: A Methodological Challenge?
TL;DR: There is a move towards direct detection and identification of enteroviruses from clinical samples using the cell culture-independent RT semi-nested PCR (RT-snPCR) assay, and it is becoming apparent that the diversity observed in certain enterovirus species might not be because they are the most evolutionarily successful, e.g., enterov virus species B(EV-B).
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Saffold virus infection in elderly people with acute gastroenteritis in Sweden.
Helena Vandesande,Kjell Edman,Elin Rondahl,Tina Falkeborn,Lena Serrander,A. Michael Lindberg +5 more
TL;DR: The first molecular typing of a Swedish SAFV isolate is described and the first report to document the circulation of SAFV among elderly people is reported, showing that SAFV is present in low abundance.
References
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Book
Virus taxonomy: classification and nomenclature of viruses. Seventh report of the International Committee on Taxonomy of Viruses.
TL;DR: This report builds on the accumulated taxonomic construction of the eight previous reports dating back to 1971 and records the proceedings of the Committee since publication of the last report in 2005.
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Community study of role of viral infections in exacerbations of asthma in 9-11 year old children.
Sebastian L. Johnston,Philip Pattemore,G. Sanderson,Sandra Smith,F Lampe,Lynn Josephs,P. Symington,S. O'Toole,S. H. Myint,D. A. J. Tyrrell +9 more
TL;DR: This study supports the hypothesis that upper respiratory viral infections are associated with 80-85% of asthma exacerbations in school age children.
Journal ArticleDOI
Mutation rates among RNA viruses
John W. Drake,John J. Holland +1 more
TL;DR: This work describes a simple relation between ribovirus mutation frequencies and mutation rates, applies it to the best (albeit far from satisfactory) available data, and observes a central value for the mutation rate per genome per replication of micro(g) approximately 0.76.
Journal ArticleDOI
Virology, epidemiology, pathogenesis, and control of enterovirus 71.
Tom Solomon,Tom Solomon,Penny Lewthwaite,David Perera,Mary Jane Cardosa,Peter McMinn,Mong How Ooi,Mong How Ooi +7 more
TL;DR: Enterovirus 71 is a major public health issue across the Asia-Pacific region and beyond, with new outbreaks occurring across Asia in regular cycles, and virus gene subgroups seem to differ in clinical epidemiological properties.