Journal ArticleDOI
Picornavirus and enterovirus diversity with associated human diseases
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TLDR
The Enterovirus genus is a prototype example of the Picornaviridae heterogeneity at both genetic and phenotypic levels and better characterization of these ubiquitous human pathogens may help to develop vaccines or antiviral treatments and to monitor the emergence of new strains.Citations
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Enterovirus persistence as a mechanism in the pathogenesis of type 1 diabetes.
TL;DR: Enteroviral persistence is the result of a virus-host coevolution combining a cell resistance to lysis through mutations or down-regulation of viral receptor, and a decrease of the viral replication by genomic modifications or the production of a stable double-stranded RNA form.
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ACBD3 Is an Essential Pan-enterovirus Host Factor That Mediates the Interaction between Viral 3A Protein and Cellular Protein PI4KB.
Heyrhyoung Lyoo,Hilde M. van der Schaar,Cristina M. Dorobantu,Huib H. Rabouw,Jeroen R.P.M. Strating,Frank J. M. van Kuppeveld +5 more
TL;DR: The role of acyl-coenzyme A binding domain containing 3 (ACBD3) in PI4KB recruitment upon enterovirus replication is revealed and the minimal domains of ACBD3 involved in recruiting PI4 KB and supporting enterov virus replication were revealed.
Journal ArticleDOI
Solar Disinfection of Viruses in Polyethylene Terephthalate Bottles
Anna Carratalà,Alex Dionisio Calado,Michael J. Mattle,Regula Meierhofer,Samuel Luzi,Tamar Kohn +5 more
TL;DR: It is demonstrated that SODIS may reduce the load of single-stranded RNA (ssRNA) viruses, such as echoviruses, particularly at high temperatures and in photoreactive matrices.
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A metagenomic comparison of endemic viruses from broiler chickens with runting-stunting syndrome and from normal birds.
TL;DR: This paper attempts to characterize the viral pathogens associated with 2–3-week-old RSS-affected and unaffected broiler chickens using next-generation sequencing and comparative metagenomics to identify a variety of enteric viruses and viral communities appropriate for further study.
Journal ArticleDOI
Essential Role of Enterovirus 2A Protease in Counteracting Stress Granule Formation and the Induction of Type I Interferon.
Linda J. Visser,Martijn A. Langereis,Huib H. Rabouw,Maryam Wahedi,Elke M Muntjewerff,Raoul J. de Groot,Frank J. M. van Kuppeveld +6 more
TL;DR: A detailed and comprehensive comparison of the effect of individual enterov virus proteases on the formation of SGs and the induction of IFN-α/β gene expression in infected cells for representative members of the enterovirus species EV-A to EV-D is presented.
References
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Book
Virus taxonomy: classification and nomenclature of viruses. Seventh report of the International Committee on Taxonomy of Viruses.
TL;DR: This report builds on the accumulated taxonomic construction of the eight previous reports dating back to 1971 and records the proceedings of the Committee since publication of the last report in 2005.
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Community study of role of viral infections in exacerbations of asthma in 9-11 year old children.
Sebastian L. Johnston,Philip Pattemore,G. Sanderson,Sandra Smith,F Lampe,Lynn Josephs,P. Symington,S. O'Toole,S. H. Myint,D. A. J. Tyrrell +9 more
TL;DR: This study supports the hypothesis that upper respiratory viral infections are associated with 80-85% of asthma exacerbations in school age children.
Journal ArticleDOI
Mutation rates among RNA viruses
John W. Drake,John J. Holland +1 more
TL;DR: This work describes a simple relation between ribovirus mutation frequencies and mutation rates, applies it to the best (albeit far from satisfactory) available data, and observes a central value for the mutation rate per genome per replication of micro(g) approximately 0.76.
Journal ArticleDOI
Virology, epidemiology, pathogenesis, and control of enterovirus 71.
Tom Solomon,Tom Solomon,Penny Lewthwaite,David Perera,Mary Jane Cardosa,Peter McMinn,Mong How Ooi,Mong How Ooi +7 more
TL;DR: Enterovirus 71 is a major public health issue across the Asia-Pacific region and beyond, with new outbreaks occurring across Asia in regular cycles, and virus gene subgroups seem to differ in clinical epidemiological properties.