Journal ArticleDOI
Picornavirus and enterovirus diversity with associated human diseases
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TLDR
The Enterovirus genus is a prototype example of the Picornaviridae heterogeneity at both genetic and phenotypic levels and better characterization of these ubiquitous human pathogens may help to develop vaccines or antiviral treatments and to monitor the emergence of new strains.Citations
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Antiviral Natural Products and Herbal Medicines
TL;DR: In this mini-review, a summary of the antiviral effects reported for several natural products and herbal medicines is summarized.
Journal ArticleDOI
Neurotropic virus infections as the cause of immediate and delayed neuropathology.
Martin Ludlow,Jeroen Kortekaas,Christiane Herden,Bernd Hoffmann,Dennis Tappe,Corinna Trebst,Diane E. Griffin,Hannah Brindle,Tom Solomon,Alan S. Brown,Debby van Riel,Katja C. Wolthers,Dasja Pajkrt,Peter Wohlsein,Byron E. E. Martina,Wolfgang Baumgärtner,Georges M. G. M. Verjans,Georges M. G. M. Verjans,Albert D. M. E. Osterhaus,Albert D. M. E. Osterhaus +19 more
TL;DR: Mechanisms that govern neuropathogenesis and immunopathogenesis of viral infections are highlighted, using examples of well-studied virus infections that are associated with these alterations in different populations throughout the world.
Journal ArticleDOI
Hand, foot and mouth disease (HFMD): emerging epidemiology and the need for a vaccine strategy
TL;DR: The development of a globally representative multivalent HFMD vaccine could be the best strategy to protect against other major emerging etiologies of HFMD such as CV-A16,CV-A6 and CV- a10.
Journal ArticleDOI
Enterovirus and parechovirus infection in children: a brief overview
TL;DR: This review is an overview of what is known from enterovirus and parechovirus infection in children and contains information about the epidemiology, pathogenesis, clinical presentation, diagnosis, treatment, and prognosis of enterov virus and paredchov virus infection inChildren.
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Probiotics in respiratory virus infections
TL;DR: More randomized, double-blind, and placebo-controlled trials in different age populations investigating probiotic dose response, comparing probiotic strains/genera, and elucidating the antiviral effect mechanisms are necessary to provide insights on the possible antiviral mechanisms of probiotics.
References
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Journal ArticleDOI
Hepatitis A virus: from discovery to vaccines.
Annette Martin,Stanley M. Lemon +1 more
TL;DR: Changes in the epidemiology of HAV may paradoxically enhance the disease burden, as greater numbers of individuals become infected at older ages when disease is more likely to be clinically evident, thus providing greater incentives for vaccine utilization.
BookDOI
Human enterovirus infections.
TL;DR: Enterovirus genetics Early events in infection Viral replication Transplantation and host cell shutoff Packaging and assembly Cell biology of enterov virus infections Host immune response to enterovirus infections.
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An Unidentified, Filtrable Agent Isolated From the Feces of Children With Paralysis.
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One hundred years of poliovirus pathogenesis
TL;DR: Understanding of poliovirus pathogenesis is still incomplete, and the dilemma is not how to answer the remaining questions, but whether there will be sufficient time to do so before global eradication of poliomyelitis leads to cessation of research on the disease.
Journal ArticleDOI
Classification of enteroviruses based on molecular and biological properties.
TL;DR: This paper presents a meta-analyses of the immune system’s response to central nervous system transplants using a probabilistic approach and shows clear patterns in response to treatment-side effects.