Plasmofluidic single-molecule surface-enhanced Raman scattering from dynamic assembly of plasmonic nanoparticles
Partha Pratim Patra,Rohit Chikkaraddy,Ravi P. N. Tripathi,Arindam Dasgupta,G. V. Pavan Kumar +4 more
TLDR
By utilizing dual excitation of plasmons at metal-fluid interface, this work creates interacting assemblies of metal nanoparticles, which may be further harnessed in dynamic lithography of dispersed nanostructures and have implications in realizing optically addressable, plasmofluidic, single-molecule detection platforms.Abstract:
Single-molecule surface-enhanced Raman scattering (SM-SERS) is one of the vital applications of plasmonic nanoparticles. The SM-SERS sensitivity critically depends on plasmonic hot-spots created at the vicinity of such nanoparticles. In conventional fluid-phase SM-SERS experiments, plasmonic hot-spots are facilitated by chemical aggregation of nanoparticles. Such aggregation is usually irreversible, and hence, nanoparticles cannot be re-dispersed in the fluid for further use. Here, we show how to combine SM-SERS with plasmon polariton-assisted, reversible assembly of plasmonic nanoparticles at an unstructured metal–fluid interface. One of the unique features of our method is that we use a single evanescent-wave optical excitation for nanoparticle assembly, manipulation and SM-SERS measurements. Furthermore, by utilizing dual excitation of plasmons at metal–fluid interface, we create interacting assemblies of metal nanoparticles, which may be further harnessed in dynamic lithography of dispersed nanostructures. Our work will have implications in realizing optically addressable, plasmofluidic, single-molecule detection platforms. Plasmonic hot-spot generation in solution is not reversible for single-molecule surface-enhanced Raman scattering, which limits its applications. Patra et al.tackle this problem by integrating this technique with thermo-plasmon-assisted reconfiguration of nanoparticles at a metal–fluid interface.read more
Citations
More filters
Journal ArticleDOI
White multi-layered polymer light emitting diode through matrix assisted pulsed laser evaporation
Fabrizio Mariano,Anna Paola Caricato,Gianluca Accorsi,C. Leo,Maura Cesaria,S. Carallo,Armando Genco,D. Simeone,T. Tunno,Maurizio Martino,Giuseppe Gigli,Marco Mazzeo +11 more
TL;DR: In this paper, a white light-emitting polymeric hetero-structured diode consisting of three stacked blue, red and green light emitting polymers is presented, which is the first proof of a light emitting diode made with multi-layer polymeric thin films emitting white light.
Journal ArticleDOI
A Simple Physically Based Phenomenological Model for the Strengthening/Softening Behavior of Nanotwinned Copper
TL;DR: In this article, a robust phenomenological model based on a modified size-dependent Voce-type constitutive equation is proposed to describe the dependence of strength on twin thickness, for nanotwinned copper (nt-Cu) polycrystals, in agreement with experiments and related atomistic simulations.
Journal ArticleDOI
Femtomolar determination of an ovarian cancer biomarker (miR-200a) in blood plasma using a label free electrochemical biosensor based on L-cysteine functionalized ZnS quantum dots.
TL;DR: A label-free electrochemical genosensor designed based on ZnS quantum dots functionalized with l-cysteine (Cys-ZnS-QDs) to detect miR-200a, as a special ovarian cancer biomarker, without using any amplification method was used.
Book ChapterDOI
In Vitro Culturing and Live Imaging of Drosophila Egg Chambers: A History and Adaptable Method.
TL;DR: This chapter discusses various culturing methods that have facilitated analyses of different stages of egg-chamber development and different types of cells within the egg chamber, and presents an optimized protocol for live culturing Drosophila egg chambers.
Journal ArticleDOI
Generalized thermoelasticity model of nonlocal strain gradient Timoshenko nanobeams
TL;DR: In this article, the authors established a thorough model for appraisal of size-dependent thermoelastic vibrations of Timoshenko nanobeams by capturing small-scale effect on both structural and thermal fields.
References
More filters
Journal ArticleDOI
Optical Constants of the Noble Metals
P. B. Johnson,R. W. Christy +1 more
TL;DR: In this paper, the optical constants for the noble metals (copper, silver, and gold) from reflection and transmission measurements on vacuum-evaporated thin films at room temperature, in the spectral range 0.5-6.5 eV.
Journal ArticleDOI
Surface plasmon subwavelength optics
TL;DR: By altering the structure of a metal's surface, the properties of surface plasmons—in particular their interaction with light—can be tailored, which could lead to miniaturized photonic circuits with length scales that are much smaller than those currently achieved.
Journal ArticleDOI
Probing Single Molecules and Single Nanoparticles by Surface-Enhanced Raman Scattering
Shuming Nie,Steven R. Emory +1 more
TL;DR: In this article, surface-enhanced Raman scattering was used to detect single molecules and single nanoparticles at room temperature with the use of surface enhanced Raman, and the intrinsic Raman enhancement factors were on the order of 10 14 to 10 15, much larger than the ensemble-averaged values derived from conventional measurements.
Journal ArticleDOI
Single Molecule Detection Using Surface-Enhanced Raman Scattering (SERS)
Katrin Kneipp,Katrin Kneipp,Yang Wang,Yang Wang,Harald Kneipp,Harald Kneipp,Lev T. Perelman,Lev T. Perelman,Irving Itzkan,Irving Itzkan,Ramachandra R. Dasari,Ramachandra R. Dasari,Michael S. Feld,Michael S. Feld +13 more
TL;DR: In this article, the first observation of single molecule Raman scattering was made using a single crystal violet molecule in aqueous colloidal silver solution using one second collection time and about $2.
Journal ArticleDOI
Biosensing with plasmonic nanosensors
TL;DR: This paper introduces the localized surface plasmon resonance (LSPR) sensor and describes how its exquisite sensitivity to size, shape and environment can be harnessed to detect molecular binding events and changes in molecular conformation.