Journal ArticleDOI
Prognostic role of pretreatment blood neutrophil-to-lymphocyte ratio in advanced cancer survivors: A systematic review and meta-analysis of 66 cohort studies
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TLDR
Overall, high pretreatment blood NLR could be an adverse prognostic indicator for advanced tumor and large-scale prospective studies investigating its survival outcomes in specific cancer type are strongly advocated.About:
This article is published in Cancer Treatment Reviews.The article was published on 2017-07-01. It has received 209 citations till now. The article focuses on the topics: Hazard ratio.read more
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Journal ArticleDOI
Neutrophil to Lymphocyte Ratio in Hospitalized COVID 19 Patients – A Study in a Tertiary Care Covid Centre in Eastern India
TL;DR: TC and NLR were significantly higher in severe cases compared to moderate cases and hence they can be utilised to triage COVID-19 cases at an early stage.
Journal ArticleDOI
Preoperative serum inflammation-based scores in medullary thyroid cancer
TL;DR: In this article , the authors evaluate the association between preoperative neutrophil-to-lymphocyte ratio (NLR), platelet-tolyckocyte ratio and systemic immune-inflammation index (SII) with MTC clinicopathological and molecular features, and their predictive value for lymph node and distant metastasis.
Journal ArticleDOI
Association between environmental chemicals co-exposure and peripheral blood immune-inflammatory indicators
TL;DR: In this article , the effect of exposure to various chemicals on immune-inflammatory biomarkers and its molecular mechanism was explored using data from 1,723 participants in the National Health and Nutrition Examination Survey (NHANES, 2011-2012), using linear regression model, weighted quantile sum regression (WQSR), and bayesian nuclear machine regression (BKMR) model.
Book ChapterDOI
Lipoproteins and the Tumor Microenvironment.
Akpedje Serena Dossou,Nirupama Sabnis,Bhavani Nagarajan,Ezek Mathew,Rafal Fudala,Andras G. Lacko +5 more
TL;DR: Specific role(s) for lipoproteins as part of these processes that facilitate (or oppose) malignant growth as they interact with specific components of the TME during tumor development and treatment are identified.
Journal ArticleDOI
Can Inflammatory Hematological Parameters be a Guide to Late-onset Fetal Growth Restriction?
Demet Aydogan Kirmizi,Emre Baser,Taylan Onat,Melike Demir Çaltekin,Mustafa Kara,Ethem Serdar Yalvaç +5 more
TL;DR: Neutrophil, lymphocyte and platelet interactions have an important role in FGR development and inflammation can be involved in the etiopathogenesis in late-onset FGR.
References
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Journal ArticleDOI
Bias in meta-analysis detected by a simple, graphical test
TL;DR: Funnel plots, plots of the trials' effect estimates against sample size, are skewed and asymmetrical in the presence of publication bias and other biases Funnel plot asymmetry, measured by regression analysis, predicts discordance of results when meta-analyses are compared with single large trials.
Journal ArticleDOI
The PRISMA Statement for Reporting Systematic Reviews and Meta-Analyses of Studies That Evaluate Health Care Interventions: Explanation and Elaboration
Alessandro Liberati,Douglas G. Altman,Jennifer Tetzlaff,Cynthia D. Mulrow,Peter C Gøtzsche,John P. A. Ioannidis,Mike Clarke,Mike Clarke,Philip J. Devereaux,Jos Kleijnen,David Moher +10 more
TL;DR: An Explanation and Elaboration of the PRISMA Statement is presented and updated guidelines for the reporting of systematic reviews and meta-analyses are presented.
Journal ArticleDOI
Quantifying heterogeneity in a meta‐analysis
TL;DR: It is concluded that H and I2, which can usually be calculated for published meta-analyses, are particularly useful summaries of the impact of heterogeneity, and one or both should be presented in publishedMeta-an analyses in preference to the test for heterogeneity.
Book
Cochrane Handbook for Systematic Reviews of Interventions
Julian P T Higgins,Sally Green +1 more
TL;DR: The Cochrane Handbook for Systematic Reviews of Interventions is the official document that describes in detail the process of preparing and maintaining Cochrane systematic reviews on the effects of healthcare interventions.
Journal ArticleDOI
Operating characteristics of a rank correlation test for publication bias.
TL;DR: In this paper, an adjusted rank correlation test is proposed as a technique for identifying publication bias in a meta-analysis, and its operating characteristics are evaluated via simulations, and the test statistic is a direct statistical analogue of the popular funnel-graph.