Prostate Cancer Genetics: Variation by Race, Ethnicity, and Geography.
TLDR
Genetic susceptibility markers have been identified from family-based studies, candidate gene association studies, and genome-wide association studies; some prostate cancer loci, including the risk loci found at chromosome 8q24, have consistent effects in all groups studied to date.About:
This article is published in Seminars in Radiation Oncology.The article was published on 2017-01-01 and is currently open access. It has received 185 citations till now. The article focuses on the topics: Prostate cancer.read more
Citations
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Cancer health disparities in racial/ethnic minorities in the United States
Valentina A. Zavala,Paige M. Bracci,John M. Carethers,Luis G. Carvajal-Carmona,Nicole B. Coggins,Marcia Cruz-Correa,Melissa Davis,Adam J. de Smith,Julie Dutil,Jane C. Figueiredo,Rena K. Fox,Kristi D. Graves,Scarlett Lin Gomez,Andrea S. Llera,Susan L. Neuhausen,Lisa A. Newman,Tung T. Nguyen,Julie R. Palmer,Nynikka R. Palmer,Eliseo J. Pérez-Stable,Sorbarikor Piawah,Erik J. Rodriquez,María Carolina Sanabria-Salas,Stephanie L. Schmit,Silvia J. Serrano-Gomez,Mariana C. Stern,Jeffrey N. Weitzel,Jun J. Yang,Jovanny Zabaleta,Elad Ziv,Laura Fejerman +30 more
TL;DR: To eliminate cancer health disparities, it will be necessary to facilitate access to, and utilisation of, health services to all individuals, and to address structural inequities, including racism, that disproportionally affect racial/ethnic minorities in the USA.
Journal ArticleDOI
Biological Effect of Soy Isoflavones in the Prevention of Civilization Diseases.
TL;DR: The purpose of this review is to present the current knowledge on the potential effects of soy isoflavone consumption with regard to civilization diseases.
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Cannabidiol—from Plant to Human Body: A Promising Bioactive Molecule with Multi-Target Effects in Cancer
Brigitta Kis,Feng Chen Ifrim,Valentina Buda,Stefana Avram,Ioana Zinuca Pavel,Diana Antal,Virgil Paunescu,Cristina Dehelean,Florina Ardelean,Zorita Diaconeasa,Codruta Soica,Corina Danciu +11 more
TL;DR: The review is designed to provide an update regarding the multi-target effects of CBD in different types of cancer, and the main focus is on the latest in vitro and in vivo studies that present data regarding the anti-proliferative, pro-apoptotic, cytotoxic, anti-invasive,Anti-antiangiogenic,anti-inflammatory, and immunomodulatory properties of CBD together with their mechanisms of action.
Journal ArticleDOI
Current Knowledge of the Potential Links between Inflammation and Prostate Cancer
T. Tony Cai,Raffaella Santi,Irene Tamanini,Ilaria Camilla Galli,Gianpaolo Perletti,Truls E. Bjerklund Johansen,Gabriella Nesi +6 more
TL;DR: Evaluation of the inflammatory component in prostate specimens could be included in routine pathology reports to lead to the introduction and optimization of novel targeted therapies.
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Increased frequency of germline BRCA2 mutations associates with prostate cancer metastasis in a racially diverse patient population.
Gyorgy Petrovics,Douglas K. Price,Hong Lou,Yongmei Chen,Lisa Garland,Sara Bass,Kristine Jones,Indu Kohaar,Amina Ali,Amina Ali,Lakshmi Ravindranath,Denise Young,Jennifer Cullen,Jennifer Cullen,Tiffany H. Dorsey,Isabell A. Sesterhenn,Stephen A Brassell,Stephen A Brassell,Inger L. Rosner,Inger L. Rosner,Doug Ross,William L. Dahut,Stefan Ambs,William D. Figg,Shiv Srivastava,Shiv Srivastava,Michael Dean +26 more
TL;DR: Germline variants of unknown significance in BRCA1/2 are more frequent in AA than CA PCa patients; however, the prevalence of pathogenic mutations were similar across the races.
References
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