Journal ArticleDOI
Purification, characterization and biological significance of mannose binding lectin from Dioscorea bulbifera bulbils
Mamta Sharma,Vishwanathreddy Hotpet,B.R. Sindhura,A. S. Kamalanathan,Bale M. Swamy,Shashikala R. Inamdar +5 more
TLDR
Glycan array analysis of DBL revealed its affinity toward high mannose N-linked glycans with enhanced affinity for terminalMannose including N- linked glycans of HIV envelope glycoprotein gp120 and has strong anti-reverse transcriptase activity.About:
This article is published in International Journal of Biological Macromolecules.The article was published on 2017-09-01. It has received 12 citations till now. The article focuses on the topics: Mannose & Glycan.read more
Citations
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Journal ArticleDOI
Overview of the Structure–Function Relationships of Mannose-Specific Lectins from Plants, Algae and Fungi
TL;DR: Because of the high specificity towards mannose these lectins are valuable tools for deciphering and characterizing the complexMannose-containing glycans that decorate both normal and transformed cells, e.g., the altered high-mannose N-glycans that often occur at the surface of various cancer cells.
Journal ArticleDOI
Chemical diversity and activity profiles of HIV-1 reverse transcriptase inhibitors from plants
TL;DR: The chemical diversity and activity profiles of HIV-1 reverse transcriptase inhibitors from plants reveal two recurring motifs: the structure of several active anti- Reverse transcriptase compounds mimics nucleoside analogues, and numerous anti-reverse transcriptase phytochemicals have pleiotropic effects and heterogenous pharmacological benefits during infection and disease.
Journal ArticleDOI
Dioscorea Plants: A Genus Rich in Vital Nutra-pharmaceuticals-A Review.
Bahare Salehi,Bilge Sener,Mehtap Kilic,Javad Sharifi-Rad,Rabia Naz,Zubaida Yousaf,Fhatuwani N. Mudau,Patrick Valere Tsouh Fokou,Shahira M. Ezzat,Mahitab H. El Bishbishy,Yasaman Taheri,Giuseppe Lucariello,Alessandra Durazzo,Massimo Lucarini,Hafiz Ansar Rasul Suleria,Antonello Santini +15 more
TL;DR: Dioscorea is a potential source of bioactive substances of interest in the prevention/treatment of several diseases, and thus represents a great challenge in developing countries, however, ethnomedicinal potential should be validated and further researches on pharmacological properties and phytochemical composition should be carried out.
Journal ArticleDOI
Advances in the Biology of Seed and Vegetative Storage Proteins Based on Two-Dimensional Electrophoresis Coupled to Mass Spectrometry
TL;DR: Progress on the biology of storage proteins and application areas in seed breeding using 2-DE-based maps is addressed and advances have translated into relevant information about meaningful traits in seedbreeding such as protein quality, longevity, gluten and allergen content, stress response and antifungal, antibacterial, and insect susceptibility.
Journal ArticleDOI
Biochemical characterisation of lectin from Indian hyacinth plant bulbs with potential inhibitory action against human cancer cells
Sanjay Naik,Ravindra Singh Rawat,Santripti Khandai,Mukesh Kumar,Sidhartha S. Jena,Mookambeswaran A. Vijayalakshmi,Sanjit Kumar +6 more
TL;DR: Morphological studies of treated cells with hyacinth lectin by AO/EB dual staining indicated that purified lectin is capable of inducing apoptosis.
References
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Journal Article
Protein Measurement with the Folin Phenol Reagent
TL;DR: Procedures are described for measuring protein in solution or after precipitation with acids or other agents, and for the determination of as little as 0.2 gamma of protein.
Journal ArticleDOI
Cleavage of Structural Proteins during the Assembly of the Head of Bacteriophage T4
TL;DR: Using an improved method of gel electrophoresis, many hitherto unknown proteins have been found in bacteriophage T4 and some of these have been identified with specific gene products.
Journal Article
Cleavage of structural proteins during the assemble of the head of bacterio-phage T4
TL;DR: Using an improved method of gel electrophoresis, many hitherto unknown proteins have been found in bacteriophage T4 and some of these have been identified with specific gene products as mentioned in this paper.
Journal ArticleDOI
Colorimetric Method for Determination of Sugars and Related Substances
TL;DR: In this article, a method was developed to determine submicro amounts of sugars and related substances using a phenol-sulfuric acid reaction, which is useful for the determination of the composition of polysaccharides and their methyl derivatives.
Journal ArticleDOI
A simplified method for cyanogen bromide activation of agarose for affinity chromatography
TL;DR: Agarose can be activated by adding cyanogen bromide, dissolved in acetonitrile, to beads suspended in a solution of sodium carbonate, and the necessity for manual titration and the use of a pH meter are eliminated.
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