Searching for an Operational Definition of Frailty: A Delphi Method Based Consensus Statement. The Frailty Operative Definition-Consensus Conference Project
Leocadio Rodríguez-Mañas,Catherine Féart,Catherine Féart,Giovanni E. Mann,Jose Viña,Somnath Chatterji,Wojtek Chodzko-Zajko,Magali Gonzalez-Colaço Harmand,Howard Bergman,Laure Carcaillon,Caroline Nicholson,Angelo Scuteri,Alan J. Sinclair,Martha Peláez,Tischa J. M. van der Cammen,François Béland,Jerome Bickenbach,Paul Delamarche,Luigi Ferrucci,Linda P. Fried,Luis Miguel Gutiérrez-Robledo,Kenneth Rockwood,Fernando Rodríguez Artalejo,Gaetano Serviddio,Enrique Vega +24 more
TLDR
There is agreement on the usefulness of defining frailty in clinical settings as well as on its main dimensions, however, additional research is needed before an operative definition of frailty can be established.Abstract:
BACKGROUND: There is no consensus regarding the definition of frailty for clinical uses. METHODS: A modified Delphi process was used to attempt to achieve consensus definition. Experts were selected from different fields and organized into five Focus Groups. A questionnaire was developed and sent to experts in the area of frailty. Responses and comments were analyzed using a pre-established strategy. Statements with an agreement more than or equal to 80% were accepted. RESULTS: Overall, 44% of the statements regarding the concept of frailty and 18% of the statements regarding diagnostic criteria were accepted. There was consensus on the value of screening for frailty and about the identification of six domains of frailty for inclusion in a clinical definition, but no agreement was reached concerning a specific set of clinical/laboratory biomarkers useful for diagnosis. CONCLUSIONS: There is agreement on the usefulness of defining frailty in clinical settings as well as on its main dimensions. However, additional research is needed before an operative definition of frailty can be established.read more
Citations
More filters
Journal ArticleDOI
Association between telomere length, frailty and death in older adults.
Mariam El Assar,Javier Angulo,José A. Carnicero,Stefan Walter,Francisco García-García,Fernando Rodríguez-Artalejo,Leocadio Rodríguez-Mañas +6 more
TL;DR: Telomere length (TL) does not predict incident frailty or mortality in older adults, suggesting that TL is not a reliable biomarker of functional age.
Journal ArticleDOI
Health outcomes of older patients colonized by multi-drug resistant bacteria (MDRB): a one-year follow-up study.
Didier Schoevaerdts,Jean-Philippe Agelas,Marie-Gabrielle Ingels,Jacques Jamart,Malorie Frennet,Te-Din Huang,Christian Swine,Youri Glupczynski +7 more
TL;DR: In this cohort of older patients, asymptomatic MDRB colonization was not significantly associated with adverse health outcomes at a one-year follow-up after hospitalization.
Journal ArticleDOI
Association of frailty with days alive at home after cardiac surgery: a population-based cohort study.
TL;DR: In this article, the authors conducted a population-based cohort study using linked health administrative data in the Canadian province of Ontario to estimate the association between frailty and days alive at home after cardiac surgery.
Journal ArticleDOI
Frailty degree and illness trajectories in older people towards the end-of-life: a prospective observational study
Jordi Amblàs-Novellas,Scott A Murray,Ramon Oller,Anna Torné,Joan Carles Martori,Sébastien Moine,Nadina Latorre-Vallbona,Joan Espaulella,Sebastià Santaeugènia,Sebastià Santaeugènia,Xavier Gómez-Batiste +10 more
TL;DR: In this paper, the authors assess the degree of frailty in older people with different advanced diseases and its relationship with end-of-life illness trajectories and survival. But, the authors do not assess the relationship between frailty degree and mortality.
Posted ContentDOI
Does the combination of resistance training and a nutritional intervention have a synergic effect on muscle mass, strength, and physical function in older adults? A systematic review and meta-analysis.
TL;DR: The addition of nutritional interventions to resistance training has no additional effect on body composition, muscle strength, or physical function, and only creatine showed synergistic effects with resistance training on muscle mass.
References
More filters
Journal ArticleDOI
Frailty in Older Adults Evidence for a Phenotype
Linda P. Fried,Catherine M. Tangen,Jeremy D. Walston,Anne B. Newman,Calvin H. Hirsch,John S. Gottdiener,Teresa E. Seeman,Russell P. Tracy,Willem J. Kop,B Gregory Burke,Mary Ann McBurnie +10 more
TL;DR: This study provides a potential standardized definition for frailty in community-dwelling older adults and offers concurrent and predictive validity for the definition, and finds that there is an intermediate stage identifying those at high risk of frailty.
Journal Article
Cardiovascular Health Study Collaborative Research Group : Frailty in older adults : evidence for a phenotype
Book
the delphi method: techniques and applications
Harold A. Linstone,Murray Turoff +1 more
TL;DR: The present model clarifies some of the conceptual problems associated with cross-impact analysis, and supplies a relatively sound basis for revising probability estimates in the limited case where interactions can be approximated by relative probabilities.
Journal ArticleDOI
The Delphi Technique: Making Sense of Consensus
Chia-Chien Hsu,Brian A. Sandford +1 more
TL;DR: The Delphi technique is well suited as a method for consensus-building by using a series of questionnaires delivered using multiple iterations to collect data from a panel of selected subjects.
Journal ArticleDOI
Classificação Internacional de Funcionalidade (CIF)
TL;DR: The present article has the objective of updating rehabilitation health professionals on the International Classification of Functioning Disability and Health (ICF) developed by the World Health Organization.
Related Papers (5)
Frailty Consensus: A Call to Action
John E. Morley,Bruno Vellas,G. Abellan Van Kan,Stefan D. Anker,Juergen M. Bauer,Roberto Bernabei,Matteo Cesari,Wm. Cameron Chumlea,Wolfram Doehner,Jonathan Evans,Linda P. Fried,Jack M. Guralnik,Paul R. Katz,Theodore K. Malmstrom,Roger McCarter,Luis Miguel Francisco Gutierrez Robledo,Kenneth Rockwood,Stephan von Haehling,Maurits Vandewoude,Jeremy D. Walston +19 more