Searching for an Operational Definition of Frailty: A Delphi Method Based Consensus Statement. The Frailty Operative Definition-Consensus Conference Project
Leocadio Rodríguez-Mañas,Catherine Féart,Catherine Féart,Giovanni E. Mann,Jose Viña,Somnath Chatterji,Wojtek Chodzko-Zajko,Magali Gonzalez-Colaço Harmand,Howard Bergman,Laure Carcaillon,Caroline Nicholson,Angelo Scuteri,Alan J. Sinclair,Martha Peláez,Tischa J. M. van der Cammen,François Béland,Jerome Bickenbach,Paul Delamarche,Luigi Ferrucci,Linda P. Fried,Luis Miguel Gutiérrez-Robledo,Kenneth Rockwood,Fernando Rodríguez Artalejo,Gaetano Serviddio,Enrique Vega +24 more
TLDR
There is agreement on the usefulness of defining frailty in clinical settings as well as on its main dimensions, however, additional research is needed before an operative definition of frailty can be established.Abstract:
BACKGROUND: There is no consensus regarding the definition of frailty for clinical uses. METHODS: A modified Delphi process was used to attempt to achieve consensus definition. Experts were selected from different fields and organized into five Focus Groups. A questionnaire was developed and sent to experts in the area of frailty. Responses and comments were analyzed using a pre-established strategy. Statements with an agreement more than or equal to 80% were accepted. RESULTS: Overall, 44% of the statements regarding the concept of frailty and 18% of the statements regarding diagnostic criteria were accepted. There was consensus on the value of screening for frailty and about the identification of six domains of frailty for inclusion in a clinical definition, but no agreement was reached concerning a specific set of clinical/laboratory biomarkers useful for diagnosis. CONCLUSIONS: There is agreement on the usefulness of defining frailty in clinical settings as well as on its main dimensions. However, additional research is needed before an operative definition of frailty can be established.read more
Citations
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Interventions Against Disability in Frail Older Adults: Lessons Learned from Clinical Trials.
Bertrand Fougère,John E. Morley,Milta O. Little,P. de Souto Barreto,P. de Souto Barreto,Matteo Cesari,Matteo Cesari,Bruno Vellas,Bruno Vellas +8 more
TL;DR: The aim of this viewpoint paper was to identify relevant studies performed to reverse or delay disability in frail older adults.
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Intramuscular short-chain acylcarnitines in elderly people are decreased in (pre-)frail females, but not in males
Marjanne D. van der Hoek,Marjanne D. van der Hoek,Arie G. Nieuwenhuizen,Ondřej Kuda,Paul G. Bos,Veronika Paluchova,Lars Verschuren,Anita M. van den Hoek,Robert Kleemann,Nic J. G. M. Veeger,Feike R. van der Leij,Feike R. van der Leij,Jaap Keijer +12 more
TL;DR: It is concluded that in (pre‐)frail old females, intramuscular total carnitine levels and short‐chain acylcarnitine Levels are decreased, and this decrease is associated with reduced physical performance and low expression of a wide range of genes critical for mitochondrial function.
Journal ArticleDOI
Reliability, Validity, and Feasibility of the Frail-VIG Index.
Anna Torné,Emma Puigoriol,Edurne Zabaleta-del-Olmo,Juan José Zamora-Sánchez,Sebastià Santaeugènia,Sebastià Santaeugènia,Jordi Amblàs-Novellas,Jordi Amblàs-Novellas +7 more
TL;DR: The Frail-VIG index is a reliable, feasible, and valid instrument to assess the degree of frailty in hospitalized and community-dwelling older people.
Journal ArticleDOI
Physical activity: A primary health quality determinant among community-dwelling geriatric women in Taiwan.
Ching Hwa Hsu,Heng Hsin Tung,Daniel L. Clinciu,Daniel L. Clinciu,Liang Kung Chen,Wei Hsian Yin,Usman Iqbal,Tsae Jyy Wang +7 more
TL;DR: As women have a longer life expectancy and experience twice the rates of depression of men particularly after menopause, healthcare providers should emphasize exercise and lifestyle changes in order to improve the quality of health in geriatric women.
How healthy is community-dwelling elderly population? Results from Southern Italy.
Francesca Guerriero,Valentina Orlando,Daniele Ugo Tari,Annalisa Di Giorgio,Antonio Cittadini,Gianluca Trifirò,Enrica Menditto +6 more
TL;DR: Polypharmacy is common in people aged 65 years and older with difficulties in activities of daily living and impaired cognition, and its prevalence raises with increasing age, according to a population-based retrospective cross-sectional study in Southern Italy.
References
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Journal ArticleDOI
Frailty in Older Adults Evidence for a Phenotype
Linda P. Fried,Catherine M. Tangen,Jeremy D. Walston,Anne B. Newman,Calvin H. Hirsch,John S. Gottdiener,Teresa E. Seeman,Russell P. Tracy,Willem J. Kop,B Gregory Burke,Mary Ann McBurnie +10 more
TL;DR: This study provides a potential standardized definition for frailty in community-dwelling older adults and offers concurrent and predictive validity for the definition, and finds that there is an intermediate stage identifying those at high risk of frailty.
Journal Article
Cardiovascular Health Study Collaborative Research Group : Frailty in older adults : evidence for a phenotype
Book
the delphi method: techniques and applications
Harold A. Linstone,Murray Turoff +1 more
TL;DR: The present model clarifies some of the conceptual problems associated with cross-impact analysis, and supplies a relatively sound basis for revising probability estimates in the limited case where interactions can be approximated by relative probabilities.
Journal ArticleDOI
The Delphi Technique: Making Sense of Consensus
Chia-Chien Hsu,Brian A. Sandford +1 more
TL;DR: The Delphi technique is well suited as a method for consensus-building by using a series of questionnaires delivered using multiple iterations to collect data from a panel of selected subjects.
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Classificação Internacional de Funcionalidade (CIF)
TL;DR: The present article has the objective of updating rehabilitation health professionals on the International Classification of Functioning Disability and Health (ICF) developed by the World Health Organization.
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