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Open AccessJournal ArticleDOI

Searching for an Operational Definition of Frailty: A Delphi Method Based Consensus Statement. The Frailty Operative Definition-Consensus Conference Project

TLDR
There is agreement on the usefulness of defining frailty in clinical settings as well as on its main dimensions, however, additional research is needed before an operative definition of frailty can be established.
Abstract
BACKGROUND: There is no consensus regarding the definition of frailty for clinical uses. METHODS: A modified Delphi process was used to attempt to achieve consensus definition. Experts were selected from different fields and organized into five Focus Groups. A questionnaire was developed and sent to experts in the area of frailty. Responses and comments were analyzed using a pre-established strategy. Statements with an agreement more than or equal to 80% were accepted. RESULTS: Overall, 44% of the statements regarding the concept of frailty and 18% of the statements regarding diagnostic criteria were accepted. There was consensus on the value of screening for frailty and about the identification of six domains of frailty for inclusion in a clinical definition, but no agreement was reached concerning a specific set of clinical/laboratory biomarkers useful for diagnosis. CONCLUSIONS: There is agreement on the usefulness of defining frailty in clinical settings as well as on its main dimensions. However, additional research is needed before an operative definition of frailty can be established.

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Posted ContentDOI

Long-Term Clinical Outcomes in Critically Ill Patients with Sepsis and Pre-existing Sarcopenia: A Retrospective Cohort Study

TL;DR: Sarcopenia has been proposed as an independent risk factor for poor short-term outcomes, although its effect on longterm outcomes remains unclear as discussed by the authors . But sarcopenia independently predicts one year mortality but is not associated with unfavorable hospital discharge disposition in critically ill patients with sepsis.
Book ChapterDOI

Exercise in Specific Diseases: Valvular Heart Disease

TL;DR: The increasing significance of cardiac rehabilitation requires support from randomized trials to establish evidence-based exercise regimens in the growing population of surgically or interventionally treated VHD patients.
Posted ContentDOI

Contribution of Frailty to Multimorbidity Patterns and Trajectories: Longitudinal Dynamic Cohort Study of Aging People (Preprint)

TL;DR: In this article , the authors used fuzzy c-means to identify and characterise multimorbidity patterns in people aged 65 years or older in the Spanish primary care database.
References
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Journal ArticleDOI

Frailty in Older Adults Evidence for a Phenotype

TL;DR: This study provides a potential standardized definition for frailty in community-dwelling older adults and offers concurrent and predictive validity for the definition, and finds that there is an intermediate stage identifying those at high risk of frailty.
Book

the delphi method: techniques and applications

TL;DR: The present model clarifies some of the conceptual problems associated with cross-impact analysis, and supplies a relatively sound basis for revising probability estimates in the limited case where interactions can be approximated by relative probabilities.
Journal ArticleDOI

The Delphi Technique: Making Sense of Consensus

TL;DR: The Delphi technique is well suited as a method for consensus-building by using a series of questionnaires delivered using multiple iterations to collect data from a panel of selected subjects.
Journal ArticleDOI

Classificação Internacional de Funcionalidade (CIF)

TL;DR: The present article has the objective of updating rehabilitation health professionals on the International Classification of Functioning Disability and Health (ICF) developed by the World Health Organization.
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