Searching for an Operational Definition of Frailty: A Delphi Method Based Consensus Statement. The Frailty Operative Definition-Consensus Conference Project
Leocadio Rodríguez-Mañas,Catherine Féart,Catherine Féart,Giovanni E. Mann,Jose Viña,Somnath Chatterji,Wojtek Chodzko-Zajko,Magali Gonzalez-Colaço Harmand,Howard Bergman,Laure Carcaillon,Caroline Nicholson,Angelo Scuteri,Alan J. Sinclair,Martha Peláez,Tischa J. M. van der Cammen,François Béland,Jerome Bickenbach,Paul Delamarche,Luigi Ferrucci,Linda P. Fried,Luis Miguel Gutiérrez-Robledo,Kenneth Rockwood,Fernando Rodríguez Artalejo,Gaetano Serviddio,Enrique Vega +24 more
TLDR
There is agreement on the usefulness of defining frailty in clinical settings as well as on its main dimensions, however, additional research is needed before an operative definition of frailty can be established.Abstract:
BACKGROUND: There is no consensus regarding the definition of frailty for clinical uses. METHODS: A modified Delphi process was used to attempt to achieve consensus definition. Experts were selected from different fields and organized into five Focus Groups. A questionnaire was developed and sent to experts in the area of frailty. Responses and comments were analyzed using a pre-established strategy. Statements with an agreement more than or equal to 80% were accepted. RESULTS: Overall, 44% of the statements regarding the concept of frailty and 18% of the statements regarding diagnostic criteria were accepted. There was consensus on the value of screening for frailty and about the identification of six domains of frailty for inclusion in a clinical definition, but no agreement was reached concerning a specific set of clinical/laboratory biomarkers useful for diagnosis. CONCLUSIONS: There is agreement on the usefulness of defining frailty in clinical settings as well as on its main dimensions. However, additional research is needed before an operative definition of frailty can be established.read more
Citations
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Surgical prehabilitation in older and frail individuals: a scoping review
Monika Sadlonova,Nicole B. Katz,Jane Jurayj,Laura E. Flores,Christopher M. Celano,Christine A. F. von Arnim,Julie K. Silver +6 more
TL;DR: In this paper , the authors reported that the 30-day mortality rate for "frail" patients who underwent the lowest-stress surgical procedures (eg, cystoscopy) was 1.6% (95% CI, 1.2% to 2.0%).
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Impact of frailty on disease-specific health status in cardiovascular disease
Dan Nguyen,Suzanne V. Arnold +1 more
TL;DR: In this article , the authors summarized the impact of frailty on health status outcomes across different cardiovascular conditions, highlighting the overlap between cardiovascular disease and frailty and emphasising that treatment should typically not be withheld based on the presence of the frailty alone.
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Malnutrición: un dominio más de la fragilidad clínica
Francisco Javier Martín-Sánchez,Cesáreo Fernández Alonso,Javier Perdigones,Juan González del Castillo +3 more
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Preclinical models of frailty: Focus on interventions and their translational impact: A review
Manish Mishra,Susan E. Howlett +1 more
TL;DR: It is suggested that preclinical frailty assessment tools are a valuable new resource to quantify the impact of interventions on overall health and to evaluate new frailty therapies, test combinations of interventions and assess interventions to enhance the ability to resist stressors in the setting of ageing.
Journal ArticleDOI
Changes in frailty status after cardiac surgery. a prospective cohort study
TL;DR: In this article , a prospective cohort of 137 patients aged 70 or more undergoing major cardiac surgery were recruited at three hospitals in Spain and assessed preoperatively and six months after surgery using the Fried scale and the Clinical Frailty Scale (CFS), and analyzed the changes in these frailty scores and the transitions between frailty status after surgery.
References
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Frailty in Older Adults Evidence for a Phenotype
Linda P. Fried,Catherine M. Tangen,Jeremy D. Walston,Anne B. Newman,Calvin H. Hirsch,John S. Gottdiener,Teresa E. Seeman,Russell P. Tracy,Willem J. Kop,B Gregory Burke,Mary Ann McBurnie +10 more
TL;DR: This study provides a potential standardized definition for frailty in community-dwelling older adults and offers concurrent and predictive validity for the definition, and finds that there is an intermediate stage identifying those at high risk of frailty.
Journal Article
Cardiovascular Health Study Collaborative Research Group : Frailty in older adults : evidence for a phenotype
Book
the delphi method: techniques and applications
Harold A. Linstone,Murray Turoff +1 more
TL;DR: The present model clarifies some of the conceptual problems associated with cross-impact analysis, and supplies a relatively sound basis for revising probability estimates in the limited case where interactions can be approximated by relative probabilities.
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The Delphi Technique: Making Sense of Consensus
Chia-Chien Hsu,Brian A. Sandford +1 more
TL;DR: The Delphi technique is well suited as a method for consensus-building by using a series of questionnaires delivered using multiple iterations to collect data from a panel of selected subjects.
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Classificação Internacional de Funcionalidade (CIF)
TL;DR: The present article has the objective of updating rehabilitation health professionals on the International Classification of Functioning Disability and Health (ICF) developed by the World Health Organization.
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