Sequential Transphosphorylation of the BRI1/BAK1 Receptor Kinase Complex Impacts Early Events in Brassinosteroid Signaling
Xiaofeng Wang,Uma Kota,Kai He,Kevin Blackburn,Jia Li,Michael B. Goshe,Steven C. Huber,Steven D. Clouse +7 more
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TLDR
A sequential transphosphorylation model in which BRI1 controls signaling specificity by direct BR binding followed by substrate phosphorylation is proposed, which suggests both conservation and distinct differences between the molecular mechanisms regulating phosphorylated-dependent kinase activation in plant and animal receptor kinases.About:
This article is published in Developmental Cell.The article was published on 2008-08-12 and is currently open access. It has received 509 citations till now. The article focuses on the topics: Kinase activity & Signal transduction.read more
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Innate immunity in plants : an arms race between pattern recognition receptors in plants and effectors in microbial pathogens
Thomas Boller,Sheng Yang He +1 more
TL;DR: It turns out that the important contribution of PTI to disease resistance is masked by pathogen virulence effectors that have evolved to suppress it.
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A receptor-like cytoplasmic kinase, BIK1, associates with a flagellin receptor complex to initiate plant innate immunity.
TL;DR: The receptor-like cytoplasmic kinase BIK1 is identified that is rapidly phosphorylated upon flagellin perception, depending on both FLS2 and BAK1, and is an essential component in MAMP signal transduction, which links the MAMP receptor complex to downstream intracellular signaling.
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The Arabidopsis NPR1 Protein Is a Receptor for the Plant Defense Hormone Salicylic Acid
Yue Wu,Di Zhang,Jee Yan Chu,Patrick Boyle,Yong Wang,Ian D. Brindle,Vincenzo De Luca,Charles Després +7 more
TL;DR: It is demonstrated that NPR1 directly binds SA, but not inactive structural analogs, with an affinity similar to that of other hormone-receptor interactions and consistent with in vivo Arabidopsis SA concentrations.
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The Arabidopsis Leucine-Rich Repeat Receptor–Like Kinases BAK1/SERK3 and BKK1/SERK4 Are Required for Innate Immunity to Hemibiotrophic and Biotrophic Pathogens
Milena Roux,Benjamin Schwessinger,Catherine Albrecht,Delphine Chinchilla,Alexandra M. E. Jones,Nick Holton,Frederikke Gro Malinovsky,Mahmut Tör,Sacco C. de Vries,Cyril Zipfel +9 more
TL;DR: This work demonstrates that the leucine-rich receptor kinases EFR and FLS2 form a ligand-induced complex with several LRR-RKs that belong to the SERK subfamily, and reveals that BAK1 and BKK1 contribute to disease resistance against the hemibiotrophic bacterium Pseudomonas syringae and the obligate biotrophic oomycete Hyaloperonospora arabidopsidis.
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Plant pattern recognition receptor complexes at the plasma membrane.
Jacqueline Monaghan,Cyril Zipfel +1 more
TL;DR: Recent studies describing the molecular interactions and protein modifications that occur between PRRs and their regulatory proteins have provided important mechanistic insight into how plants avoid infection and achieve immunity.
References
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A flagellin-induced complex of the receptor FLS2 and BAK1 initiates plant defence
Delphine Chinchilla,Cyril Zipfel,Cyril Zipfel,Silke Robatzek,Birgit Kemmerling,Thorsten Nürnberger,Jonathan D. G. Jones,Georg Felix,Georg Felix,Thomas Boller +9 more
TL;DR: BAK1 is shown to have a functional role in PRR-dependent signalling, which initiates innate immunity, and evidence is provided that FLS2 and BAK1 form a complex in vivo, in a specific ligand-dependent manner, within the first minutes of stimulation with flagellin.
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A Putative Leucine-Rich Repeat Receptor Kinase Involved in Brassinosteroid Signal Transduction
Jianming Li,Joanne Chory +1 more
TL;DR: The identification of 18 Arabidopsis dwarf mutants that are unable to respond to exogenously added brassinosteroid, a phenotype that might be expected for brass inosteroid signaling mutants.
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BAK1, an Arabidopsis LRR Receptor-like Protein Kinase, Interacts with BRI1 and Modulates Brassinosteroid Signaling
BRI1/BAK1, a Receptor Kinase Pair Mediating Brassinosteroid Signaling
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A Putative Leucine-Rich Repeat Receptor Kinase Involved in Brassinosteroid Signal Transduction
Jianming Li,Joanne Chory +1 more